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Statins can effectively lower high cholesterol, and many individuals take rosuvastatin, one member of this drug class. New research based on patient health records and published in Journal of the American Society of Nephrology suggests that rosuvastatin, especially at higher doses, may have damaging effects on the kidneys. Reports had linked rosuvastatin with signs of kidney damage—hematuria (blood in the urine) and proteinuria (protein in the urine)—at the time of its approval by the U.S. Food and Drug Administration, but little post-marketing surveillance exists to assess real-world risk. To investigate, Jung-Im Shin, MD, Ph.D. (Johns Hopkins Bloomberg School of Public...

Telomeres (red) protect your DNA. (NIH Image Gallery/Flickr/CC BY-NC 2.0) Damage to the ends of your chromosomes can create "zombie cells" that are still alive but can't function, according to our recently published study in Nature Structural and Molecular Biology. When cells prepare to divide, their DNA is tightly wound around proteins to form chromosomes that provide structure and support for genetic material. At the ends of these chromosomes are repetitive stretches of DNA called telomeres that form a protective cap to prevent damage to the genetic material. However, telomeres shorten each time a cell divides. This means that as...

Alzheimer’s disease is a brain disorder that gradually impairs thinking and memory abilities as well as the capacity to do even the most basic activities. The researchers believe that new treatments and medications for the condition might result from the findings More than 5.8 million people in the United States are affected by Alzheimer’s disease (AD), the most prevalent form of dementia. AD is a progressive neurodegenerative disorder. Scientists have identified a few gene variants that raise the risk of Alzheimer’s; the APOE 4 allele is the most well-known of them for individuals over the age of 65. Although there...

Diesel fuel is a staple for the farmers and truckers who supply Americans with their essential needs – and its price has skyrocketed in recent months, driven by inflation to far outstrip regular gasoline in price hikes. AP reports diesel fuel was averaging $5.52 a gallon nationally Tuesday — up a dizzying 68 percent from a year ago, when it was selling for just $3.28. By comparison, a gallon of regular gasoline is averaging $4.50, up 42 percent from a year ago. Gasoline prices have eased somewhat in recent weeks while diesel has remained chronically high, with American refineries operating...

America is finally waking up to the fact that poisonous, divisive ideas are proliferating in public education, from pre-K to graduate school. The question is how to push back against such ideas. Solutions are easier in K-12; primary and secondary teachers do not have the same protections of academic freedom that college faculty have, and the K-12 curriculum is more tightly controlled by state agencies. The issue is more complex in academia, where academic freedom reigns and the curriculum is controlled by a decentralized faculty. The situation is also more dire at the college level: Higher education is where the...

Two new treatments for Crohn's disease showed roughly equal performance in a clinical trial. This allows clinicians and patients to make treatment choices based on tolerance, according to Stephen Hanauer, MD. Crohn's disease (CD) is a chronic, progressive inflammatory bowel disease, causing abdominal pain, weight loss and fatigue. Treatment for CD has typically focused on alleviating symptoms to achieve clinical remission using corticosteroids or immunomodulators, but a need for more effective treatment remains. "While there are numerous therapies and mechanisms of action for drugs approved for moderate-severe Crohn's disease there has been a therapeutic ceiling as far as outcomes are...

Former Bill Clinton adviser Dick Morris predicted Tuesday on Newsmax TV’s “National Report” that former Secretary of State Hillary Clinton would run against former President Donald Trump in the 2024 presidential race.When asked if Trump will run in 2024, Morris said, “Yes, and he’ll be the Republican nominee. He will probably get it by acclamation. I don’t think there’ll be a primary. He will win the election. And his opponent is going to be Hillary Clinton.”He continued, “Let me explain that. Already the Democrats are pressuring by not to run because they see what a disaster he would be. And...

Former Trump acting chief of staff Mick Mulvaney said Tuesday on “CNN Tonight” that he hoped former President Donald Trump doesn’t run for president in 2024.Anchor Laura Coates asked, “If he were to run for re-election yet again, we don’t know if he intends to do that. If he is the RNC nominee, do you intend to vote for him?”Mulvaney said, “I am one of those Republicans who hopes the former President Trump doesn’t run. In all fairness, we don’t need him anymore. He changed our party. We have a lot of folks, a new generation of folks, Ron DeSantis,...

...another take, I don't know how reliable it is, on why gas prices are high...

The Biden administration has abruptly withdrawn American support for the Eastern Mediterranean (EastMed) pipeline, a project aimed at shipping natural gas from Israel to European markets. The White House said the project was antithetical to its "climate goals." In reaching its decision, which effectively kills EastMed, the White House appears to have caved to pressure from Turkish President Recep Tayyip Erdoğan, who has vociferously opposed the underwater pipeline because it would bypass Turkey. Biden's decision — reportedly coordinated with Turkey but reached without consulting Israel, Greece or Cyprus, the main countries involved in the project — undercuts three of the...

In case you missed it over the weekend, Volodymyr Zelensky abruptly fired his nation’s top prosecutor along with the head of Ukraine’s intelligence agency. Several other lower-ranking officials were given the boot as well. Given the lack of any recent news suggesting that these officials had failed to perform their duties, some analysts have been forced to consider the possibility that Zelensky may have had “other motives” for removing them. Perhaps rather than not doing their jobs well enough, they may have been doing them too well. Most of the American media has been endlessly cheerleading for the Ukrainian government...

The GOP’s newest legislator, Rep. Mayra Flores (R-TX), is defending her Thursday vote to help get green cards to the adult children of the Fortune 500’s foreign contract workers and managers, who take jobs and career opportunities from Americans. “Amnesty was not passed last week!” Flores said in a July 17 tweet. “An amendment in the NDAA bill gave legally documented children of LEGAL VISA workers the ability to remain in the United States with their parents. Stop the misinformation and stay focused on taking back the house this November!!”

A former teacher from the West Contra Costa Unified School District has been detained and accused of assaulting a kid in 2021. Jane Shetterly, 42, of Martinez, was charged with 12 felonies, including eight charges of alleged specified sexual acts on a kid and three counts of lewd acts on children. She was also charged with one count of making improper contact with a minor. According to court documents, Shetterly entered a not guilty plea during her arraignment before Judge Rebecca Hardie on July 11. After the mother of the alleged victim informed police that she had discovered proof her...

Instead of The Boston Strangler, we now have the DC Strangler. Better known as The Federal Reserve and their war on inflation. US existing home sales crashed -14.24% YoY and -5.40% MoM in June as The Fed tightens its icy grip on the housing market. Existing home sales were lower than expected at 5.12 million home sold SAAR. Median price for existing home sales declined to 13.27% YoY as inventory available for sale remains MIA. And The Fed’s balance sheet is still out in force. The US housing market in terms of sales has entered a bear market, but with...

Three out of 4 middle class households report falling behind the rising cost of living as inflation continues to soar., according to a new poll. Primerica released the report, which found that 75% of middle-income families “say their income is falling behind the cost of living,” an eight-point rise since March. The poll found only 16% of those surveyed think they will be better off financially in a year. Surveyed American middle-income families cited inflation as a top concern. The U.S. Bureau of Labor Statistics’ latest federal inflation data showed a 9.1% increase in consumer prices in the past year...

Nearly five months into its senseless war against Ukraine, Russia has concocted a wild new explanation for why the Kremlin’s plans for a quick takeover fell apart so spectacularly—because Ukrainian troops were turned into superhuman killing machines during “secret experiments” in American-run biolabs, of course. Never mind the myriad reports of Russian troops refusing to fight by the thousands, sabotaging their own shoddy equipment and even deliberately wounding themselves to abandon the war, Russian lawmakers claim the real setback for Moscow was “drugged up” Ukrainian soldiers. That claim was made Monday by two Russian lawmakers heading up a commission to...

The steamship Roanoke arrived at this port last night, from New-Orleans on the 12th inst., to which date she brings our files of New-Orleans papers We give interesting extracts below. We are indebted to Purser REQUA, of the Roanoke, for the prompt delivery of our news packages. NEW ORDERS AND REGULATIONS. How GAMBLERS AND "UNCOMMON" WOMEN ARE DISPOSED OF. HEADQUARTERS DEPARTMENT OF THE GULF, NEW-ORLEANS, July 10, 1862. SPECIAL ORDER NO. 179. -- JOHN H. LARUE, being by his own confession a vagrant, a person without visible means of support, and one who gets his living by playing cards, is...

For months, we have been told by the Biden administration that the reason for the high gas price is Vladimir Putin’s war on Ukraine. The purpose of those talking points is to divert blame from Biden’s policies to destroy the fossil fuel industry. Now that prices have come down a little they are claiming credit for the price decline. Here's the latest from Biden's White House economic advisor Jared Bernstein, in a press briefing off the White House website: While there’s a lot that goes into setting the global oil and gas price, the historic actions taken by President Biden...

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The Interpipe Pipe and Wheel Holding sent a vessel loaded with pipes to the United States for the first time since the beginning of the war in July, it plans to send a second vessel in July. Interpipe CEO Andrii Korotkov said this in an interview for Forbes, Ukrainian News Agency reports. "At the beginning of the third 10 days of June, for the first time since the beginning of the war, Interpipe sent the first ship with pipes to the USA. I hope that on July 20 we will send the second one. Currently, the USA maintains a 23.75%...