Free Republic

Scientists at Kumamoto University have unveiled a novel compound, HPH-15, which has dual effects: reducing blood glucose levels and combating fat accumulation. This breakthrough represents a significant advancement in diabetes treatment innovation. Type 2 diabetes, a condition affecting millions worldwide, is often accompanied by complications such as fatty liver and insulin resistance, posing challenges for current treatment methods. The research team, led by Visiting Associate Professor Hiroshi Tateishi and Professor Eiichi Araki, has identified HPH-15 as a promising alternative to existing medications like metformin.

Hooligans in Florida terrorized motorists, including one with a baby on board, and set a fire in a chaotic street takeover last month, according to shocking footage. Sportscar drivers accompanied by dozens of belligerent spectators took over the intersection of the South John Young Parkway and Central Florida Parkway on Nov. 30, the Orange County Sheriff’s Office said — turning the roadway into a hellscape for innocent passersby Video posted by the Orange County Sheriff’s Office shows fire set to the road right outside the Ritz-Carlton Orlando, with flashy coupes performing smoke-laden donuts and fiendish hangers-on attacking cars as they...

Controversial psychologist Jordan Peterson has fled Canada as liberals push to pass legislation that he says will suppress free speech and turn the country into a “totalitarian hellhole.” Speaking in a recent episode of his daughter’s show, “The Mikhaila Peterson Podcast,” Peterson said he opted to move to the US over the contentious bill, C-63, and ongoing feud with the College of Psychologists of Ontario. “The issue with the College of Psychologists is very annoying, to say the least, and the new legislation that the liberals are attempting to push through, Bill C-63, we’d all be living in a totalitarian...

Luigi Mangione’s body language as he was escorted into a Pennsylvania courthouse gives insight into the accused killer’s mindset, according to a body language expert. Mangione, accused of killing UnitedHealthcare CEO Brian Thompson in Manhattan, was arrested in Altoona, Pennsylvania, on Monday when a McDonald’s customer saw he resembled images of the suspect in the shooting. Charged in Pennsylvania with forgery and carrying a firearm without a license, he has not waived his right to an extradition hearing to face murder charges in New York. As he was escorted into Blair County Court on Tuesday by a cadre of officers,...

Albertsons said Wednesday that it has terminated a $25 billion merger agreement with Kroger and will sue the grocery giant, alleging the company didn’t do enough to get the deal done. Judges in Washington and Oregon on Tuesday blocked the deal, delivering a win to federal regulators and consumer advocates who argued the merger could harm competition, consumers and workers and push prices up. “Rather than fulfill its contractual obligations to ensure that the merger succeeded, Kroger acted in its own financial self-interest, repeatedly providing insufficient divestiture proposals that ignored regulators’ concerns. Kroger’s self-serving conduct, taken at the expense of...

A disgruntled Utah man smashed his car into the storefront of a dealership he had bought it from earlier that day after he was allegedly denied a refund when he discovered his new ride had mechanical issues. Michael Lee Murray, 35, bought a used Subaru Outback from the Tim Dahle Mazda Southtowne car dealership in Sandy, a city in the Salt Lake City metropolitan area, for $4,000 on Monday morning, according to Fox 13 News. However, Murray alleged that he was sold a “lemon” — a vehicle whose manufacturing issues jeopardize the driver’s safety — soon after he snagged the...

Researchers at the University of Massachusetts Amherst investigated wind and weather patterns to predict the timeline of nuclear fallout, including the paths through which radiation would spread throughout the country. Experts agree that the Midwest, where 450 ballistic missile silos are stored — particularly Montana, North Dakota and Nebraska — would be the most likely primary target as detonating just two of those storehouses could cause an explosion equal to 100,000 tons of TNT, per Scientific American. Exposure to radiation poisoning from a nuclear attack would guarantee death for an estimated 300 million Americans within four days of detonation. Citizens...

Documentary about the assassination of President John F. Kennedy, with testimony from the "man on the grassy knoll" himself, James E. Files. At first, reluctant to talk, Files eventually confessed, implicating organized crime members, Charles Nicoletti, Johnny Roselli, and Sam Giancana, as well as his own role in the crime of the century. Transcript linked below video.

Sources within the police community told the New York Post that the UnitedHealthcare CEO’s killer traveled to NYC on a Greyhound bus from Atlanta last month. The bus on which the killer is believed to have traveled originated in Atlanta, however, authorities are not certain as whether the killer boarded the bus there or climbed aboard at a stop along the way. Breitbart News reported 50-year-old Thompson was shot and killed outside the Hilton Hotel in Midtown Manhattan just after 6:45 a.m. on Wednesday. A manhunt for the killer was immediately launched and today marks the third day of the...

Move over cocaine sharks, here come the fentanyl dolphins … An alarming number of bottlenose dolphins in the Gulf of Mexico were found to have traces of fentanyl in their system, shocking scientists with a horrifying twist to the drug epidemic. Traces of the powerful synthetic opioid was first found inside a dead dolphin that was floating in the gulf water when it was then examined by researchers from Texas A&M-Corpus Christi in Sept. 2020. What was supposed to be a routine analysis of blubber turned into years-long research — with more than a third of the dolphins tested also...

Kelly Powers, a commentator on Fox News, died this week from brain cancer. Powers was 45 years old. An obituary posted online for Powers called her “a brave and beautiful soul who could make friends anywhere she went.” The former surgeon and medical expert was a regular commentator on the network and a guest on programs like “Red Eye” and “Fox and Friends.” In 2020, she was diagnosed with Glioblastoma, a severe form of brain cancer, according to a GoFundMe page set up for her family. After three brain surgeries, multiple rounds of radiation, chemotherapy, and immunotherapy, her cancer returned...

"What's the best car?" Getting asked that question is an occupational hazard in this business. (And, yes, we realize that it's not actually hazardous, at least compared with the occupational dangers faced by, say, ironworkers who build skyscrapers or zookeepers who feed lions.) When you drive and test hundreds of cars every year—as our editorial team collectively does—it's a natural query. And our annual 10Best awards provide the answer. Since 1983, we've been conducting this exercise: We identify the very best of what's available, not merely our favorite new models introduced for a given year. An onslaught of new or...

The mid-size luxury SUV segment is burgeoning with a wealth of choices, which can make it tough for shoppers to choose the right one for them. There are so many choices that come in all different sizes and shapes, but fortunately, they are all equipped with similar features, so it's hard to go wrong. Gone are the days when lackluster craftsmanship and questionable reliability were legitimate issues. Nowadays, luxury automakers imbue their cars with an impeccable quality that buyers are spoiled for choice. And if anyone is having trouble choosing, here are some of the best luxury mid-size SUVs in...

Does anyone having any suggestions for a password generator that is either online, or other? I see a few online free sites, but don't know if they are bogus or questionable. I get tired of attempting to create strong passwords, especially when using a website that requires at least 15 various numbers, characters, etc. Thanks

Winter weather is making its presence known across the U.S. as millions of people deal with the onslaught of a long-duration, lake-effect snowstorm that has paralyzed communities downwind of the Great Lakes. And to make matters worse, rounds of arctic air will continue to invade the country and send temperatures tumbling below freezing in cities as far as the Southeast. The FOX Forecast Center said the arctic blast from Canada has been sweeping across the central and eastern U.S. Temperatures in cities in the northern Plains plummeted below zero over the weekend, and wind chills made it feel even colder....

There are few treatment decisions more difficult for families and loved ones to make than those surrounding the use of artificial nutrition and hydration in the seriously or terminally ill person:“Should nutrition be given intravenously if my wife’s gut isn’t working right?”“Should intravenous fluids be given to my father when he stops drinking and becomes dehydrated?”“Should a feeding tube be placed if my mother can’t swallow without choking?”Family members agonize over these questions, especially if they are not given clear explanations about the effectiveness or lack of effectiveness of various available treatments, and what kind of burdens, side effects and...

A Brooklyn straphanger was randomly shoved onto subway tracks by a woman in a gray trench coat Sunday morning, cops say. The 43-year-old victim was standing on a southbound platform at the Kosciuszko Street station in Bedford-Stuyvesant around 9 a.m. when his unidentified assailant in a long coat suddenly pushed him onto the J train tracks, the NYPD and police sources told The Post.

December 7 Strauss: DIE FRAU OHNE SCHATTEN December 21 Mozart: THE MAGIC FLUTE January 4 Offenbach: LES CONTES D'HOFFMANN January 11 Verdi: RIGOLETTO January 18 Puccini: TOSCA January 25 at 12:30 PM Verdi: AIDA February 1 Verdi: LA TRAVIATA February 22 Verdi: FALSTAFF March 1 Bizet: CARMEN March 8 Puccini: LA BOHÈME March 15 Beethoven: FIDELIO April 12 Mozart: DIE ZAUBERFLÖTE April 26 Mozart: LE NOZZE DI FIGARO May 3 Verdi: IL TROVATORE May 31 Rossini: IL BARBIERE DI SIVIGLIA

Holy cow! A recently demoted Brooklyn priest whose church finances are under federal investigation has an impressive real estate portfolio worth more than $2 million, including a house in the Hamptons and a pricey waterfront condo in Florida, a review of records by The Post reveal. Monsignor Jamie Gigantiello, who had his pastoral duties yanked at Our Lady of Mount Carmel — Annunciation of the Blessed Virgin Mary last week even peddled a $2,000-a-week timeshare on the resort island of St. Martin on Facebook in October, the review found.

There's a southern migration happening in the U.S. right now, and it's not because of the weather. The National Association of Realtors' 2024 Migration Trends report released this week shows Southern states dominated in attracting the most people to move within their borders last year, and only 1% of those who moved said they did so because of climate-related reasons, according to its analysis of U.S. Census Bureau data.