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Keyword: maculardegeneration

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  • Study finds up to 30% of patients with wet macular degeneration can safely stop eye injections (ApoB100 expression found through tests)

    In a preliminary study of people with "wet" age-related macular degeneration, researchers report that as many as a third of those may be able to safely stop eye injection therapy without further vision loss. Age-related macular degeneration (AMD) is the most common cause of vision loss among people age 50 and older. The majority of those who lose vision from the condition have the "wet" form. Treatment of wet AMD requires monthly or bimonthly injections of drugs called anti-VEGF—or anti-vascular endothelial growth factor—into the eye. Anti-VEGF agents can slow or stop the growth of the leaky blood vessels and, in...
  • Prozac pegged as potential 1st treatment for leading cause of blindness

    10/21/2021 9:35:28 AM PDT · by Red Badger · 28 replies
    https://medicalxpress.com ^ | 21 OCTOBER 2021 | by University of Virginia
    An antidepressant best known as Prozac could offer the first treatment for the leading cause of blindness among people over 50, new research from the University of Virginia School of Medicine suggests. UVA's Bradley D. Gelfand, Ph.D., and collaborators have found early evidence that the drug fluoxetine may be effective against atrophic (or "dry") age-related macular degeneration, a condition that affects nearly 200 million people worldwide. The drug has shown promise in the scientists' lab tests and animal models, and the researchers bolstered by their results by examining two huge insurance databases encompassing more than 100 million Americans. That analysis...
  • Scientists Reverse the Aging Clock: Restore Age-Related Vision Loss Through Epigenetic Reprogramming

    12/02/2020 8:22:02 AM PST · by Red Badger · 40 replies
    https://scitechdaily.com ^ | December 2, 2020 | By Harvard Medical School
    Proof-of-concept study represents first successful attempt to reverse the aging clock in animals through epigenetic reprogramming. Scientists turned on embryonic genes to reprogram cells of mouse retinas. Approach reversed glaucoma-induced eye damage in animals. Approach also restored age-related vision loss in elderly mice. Work spells promise for using same approach in other tissues, organs beyond the eyes. Success sets stage for treatment of various age-related diseases in humans. ========================================================== ========================================================== Harvard Medical School scientists have successfully restored vision in mice by turning back the clock on aged eye cells in the retina to recapture youthful gene function. The team’s work,...
  • New research shows blue light from electronics leading to blindness

    08/10/2018 5:11:11 AM PDT · by Leaning Right · 18 replies
    WTOL ^ | August 9th 2018 | Amanda Fay
    Our cell phones are practically connected to us. Now, scientists at the University of Toledo say the blue light that comes from electronics is doing permanent damage to our vision. A dark room at the University of Toledo is where researchers have found blue light, specifically, leads to macular degeneration.
  • Drug shows promise against vision-robbing disease in seniors

    06/21/2017 6:42:45 PM PDT · by Innovative · 10 replies
    ABC News ^ | June 21, 2017 | lauran Neergaard
    An experimental drug is showing promise against an untreatable eye disease that blinds older adults — and intriguingly, it seems to work in patients who carry a particular gene flaw that fuels the damage to their vision. Age-related macular degeneration, or AMD, is the leading cause of vision loss among seniors, gradually eroding crucial central vision. There are different forms but more than 5 million people worldwide, and a million in the U.S., have an advanced type of so-called "dry" macular degeneration that has no treatment. First patients may notice blurriness when they look straight ahead. Eventually many develop blank...
  • Anyone know about "Charles Bonnet Syndrome"? (Vanity)

    05/21/2017 7:19:36 PM PDT · by RushIsMyTeddyBear · 58 replies
    My wonderful step-father (WW2 Vet) is experiencing delusions. He has Macular Dejeneration and Dementia. Noticed, today, he thinks people are "in the household ". Very agitated. Talked to many "people" in the room.
  • MEDICAL BREAKTHROUGH: EastEnders star June Brown one of first to get miracle eye surgery

    04/09/2017 11:16:31 PM PDT · by blueplum · 21 replies
    The Express ^ | 09 April 2017 5:30pm | Lucy Johnston, Exclusive
    ....The lens surgery helps readjust the nerve signals in the brain to access the remaining healthy parts of retina. The Eyemax Mono technology will be introduced to UK surgeons at the Royal College of Ophthalmologists annual meeting in Liverpool next month. More than 5,000 surgeons from around the world have already asked for the technology. The procedure, which can take up to five minutes but which was achieved in just 60 seconds with June, will be made available to eye surgeons across the UK and ....
  • An effective eye drug is available for $50. But many doctors choose a $2,000 alternative

    12/08/2013 10:32:42 AM PST · by Veto! · 49 replies
    Washington Post ^ | 12/7/13 | Peter Whoriskey, Dan Keating
    The two drugs have been declared equivalently miraculous. Tested side by side in six major trials, both prevent blindness in a common old-age affliction. Biologically, they are cousins. They’re even made by the same company...
  • Ingredient in red wine may prevent some blinding diseases

    06/25/2010 3:32:06 AM PDT · by decimon · 9 replies
    Washington University in St. Louis ^ | June 24, 2010 | Jim Dryden
    Resveratrol — found in red wine, grapes, blueberries, peanuts and other plants — stops out-of-control blood vessel growth in the eye, according to vision researchers at Washington University School of Medicine in St. Louis. The discovery has implications for preserving vision in blinding eye diseases such as diabetic retinopathy and age-related macular degeneration, the leading cause of blindness in Americans over 50. The formation of new blood vessels, called angiogenesis, also plays a key role in certain cancers and in atherosclerosis. Conducting experiments in mouse retinas, the researchers found that resveratrol can inhibit angiogenesis. Another surprise was the pathway through...
  • Gene Therapy Transforms Eyesight Of 12 People With Rare Visual Defect

    10/24/2009 2:00:36 PM PDT · by Steelfish · 10 replies · 517+ views
    LATimes ^ | October 24th 2009
    Gene Therapy Transforms Eyesight Of 12 People With Rare Visual Defect A single injection in a patient's eye brings 'astounding' results. The findings may offer hope for those with macular degeneration and retinitis pigmentosa. Thomas H. Maugh II October 24, 2009 Pennsylvania researchers using gene therapy have made significant improvements in vision in 12 patients with a rare inherited visual defect, a finding that suggests it may be possible to produce similar improvements in a much larger number of patients with retinitis pigmentosa and macular degeneration. The team last year reported success with three adult patients, an achievement that was...
  • Omega-3 fatty acids appear to impact AMD progression

    06/18/2009 3:01:23 PM PDT · by decimon · 23 replies · 704+ views
    Tufts University, Health Sciences ^ | Jun 18, 2009 | Unknown
    BOSTON (June 18, 2009) - Omega-3 fatty acids found in fatty fish such as tuna and salmon may protect against progression of age-related macular degeneration (AMD), but the benefits appear to depend on the stage of disease and whether certain supplements are taken, report researchers at the Laboratory for Nutrition and Vision Research (LNVR), Jean Mayer USDA Human Nutrition Research Center on Aging (HNRCA) at Tufts University. The researchers calculated intakes of docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) from dietary questionnaires administered to 2,924 men and women, aged 55 to 80 years, participating in an eight-year supplement trial, the...
  • B vitamins, folic acid may protect vision - Supplements may guard against macular degeneration

    02/25/2009 11:10:19 AM PST · by neverdem · 8 replies · 478+ views
    Science News ^ | February 24th, 2009 | Nathan Seppa
    A combination of vitamin B-6, vitamin B-12 and folic acid might protect women against age-related macular degeneration, the leading cause of blindness in the elderly, a new study finds. Women taking this trio of vitamins in amounts well beyond the recommended daily doses were one-third less likely to develop macular degeneration than were people taking placebos, researchers report in the Feb. 23 Archives of Internal Medicine. Cigarette smoking is known to increase a person’s likelihood of developing macular degeneration. Other than not smoking, there is little a person can do to limit risk, says study coauthor William Christen, an epidemiologist...
  • Hurler regains sight after 'miracle' diet supplement (macular degeneration)

    02/13/2008 10:59:53 AM PST · by LibWhacker · 64 replies · 1,055+ views
    Former Cork club hurler Jimmy Aherne wept when he was told he would be blind within three years. The father-of-four -- who is a second cousin to hurling legend Christy Ring -- was diagnosed with age-related macular degeneration (AMD). The condition is cruel, as it has traditionally been untreatable. For decades, thousands of pensioners who lost their sight were simply told they had "old people's blindness" and that nothing could be done for them. But today, almost 12 months after that shocking diagnosis, the deterioration in Jimmy's eyesight has been halted and his good eye has improved to the point...
  • Zebrafish study may point way to blindness cure

    08/03/2007 4:29:16 PM PDT · by Coleus · 1 replies · 276+ views
    yahoo ^ | 08.01.07 | Ben Hirschler
    The ability of zebrafish to regenerate damaged retinas has given scientists a clue about restoring human vision and could lead to an experimental treatment for blindness within five years. British researchers said on Wednesday they had successfully grown in the laboratory a type of adult stem cell found in the eyes of both fish and mammals that develops into neurons in the retina. In future, these cells could be injected into the eye as a treatment for diseases such as macular degeneration, glaucoma and diabetes-related blindness, according to Astrid Limb of University College London's (UCL) Institute of Ophthalmology. Damage to...
  • Study Finds Dietary Link to Risk of Eye Disorder

    07/17/2007 1:10:36 PM PDT · by neverdem · 41 replies · 1,652+ views
    NY Times ^ | July 17, 2007 | NICHOLAS BAKALAR
    Certain kinds of carbohydrates may play a role in the development of age-related macular degeneration, an incurable degenerative eye disease that is a leading cause of blindness in older adults. A new study has found that eating carbohydrate-rich food with a high glycemic index — a measure of a food’s potential to raise blood glucose levels — is associated with the development of the disorder. The glycemic index is a measure of how fast carbohydrates are metabolized — the faster they are broken down into glucose, the higher the glycemic index. Simple carbohydrates, like those in cakes and cookies, cheese...
  • 45-minute operation to restore sight to millions

    06/05/2007 5:16:34 PM PDT · by The Magical Mischief Tour · 38 replies · 1,328+ views
    Daily Mail ^ | 6th June 2007 | FIONA MACRAE
    A revolutionary technique being developed by British scientists could cure blindness in millions of people around the world. The first 45-minute operations could take place within five years and could be as commonplace as cataract surgery in a decade. The improvement is likely to be great enough to transform lives, allowing the blind to regain the ability to carry out everyday tasks such as reading or driving. The pioneering stem cell surgery tackles age-related macular degeneration (AMD), the most common cause of blindness in the elderly. There are about 300,000 sufferers in this country and the number is expected to...
  • Prayers for Antoinette

    03/11/2007 7:32:10 AM PDT · by janereinheimer · 27 replies · 286+ views
    Please join me in prayer for Antoinette who has lost vision in her right eye due to macular degeneration. I pray to Almighty God that this is a temporary situation only and that vision will be restored through the healing power of our Lord Jesus Christ.
  • Young People Unaware That Smoking Causes Blindness

    02/18/2007 9:18:47 AM PST · by Eric Blair 2084 · 31 replies · 738+ views
    Earth Times ^ | 2/6/2007 | Ravi Chopra and Grant Junkie
    LONDON - The Royal National Institute of the Blind (RNIB) has said that young people are unaware of the fact that smoking could lead to blindness. The charity says that if the government were to fund a national campaign, then young people could give up smoking. For evidence, it cites an article in the British Journal of Ophthalmology, which found that the fear of blindness was more of a deterrent than anything else. The study surveyed around 250 clubbers in Winchester, Manchester and Southampton. All responders were aged between 16 to 18 years. On a scale of 5, most rated...
  • 'Bionic' eye implants look ahead

    02/16/2007 3:23:11 AM PST · by Jedi Master Pikachu · 48 replies · 2,913+ views
    BBC ^ | Friday, February 16, 2007 | Jonathan Fildes
    A bionic eye implant that could help restore the sight of millions of blind people could be available to patients within two years. US researchers have been given the go-ahead to implant the prototype device in 50 to 75 patients. The Argus II system uses a spectacle-mounted camera to feed visual information to electrodes in the eye. Patients who tested less-advanced versions of the retinal implant were able to see light, shapes and movement. "What we are trying to do is take real-time images from a camera and convert them into tiny electrical pulses that would jump-start the otherwise...
  • Silicon retina mimics biology for a clearer view

    10/23/2006 5:51:25 PM PDT · by annie laurie · 12 replies · 572+ views
    NewScientistTech ^ | 20 October 2006 | Tom Simonite
    A silicon chip that faithfully mimics the neural circuitry of a real retina could lead to better bionic eyes for those with vision loss, researchers claim. About 700,000 people in the developed world are diagnosed with age-related macular degeneration each year, and 1.5 million people worldwide suffer from a disease called retinitis pigmentosa. In both of these diseases, retinal cells, which convert light into nerve impulses at the back of the eye, gradually die. Most artificial retinas connect an external camera to an implant behind the eye via a computer (see 'Bionic' eye may help reverse blindness). The new silicon...