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An international study has revealed that melatonin, known for its ability to regulate the sleep/wake cycle, can restore the composition of muscle fibers and protect skeletal muscle from damage caused by obesity and type 2 diabetes, known as "diabesity." The results show that this hormone improves mitochondrial function, reduces cellular stress and prevents programmed cell death, offering a new therapeutic strategy. The study showed the administration of melatonin to obese and diabetic rodents for 12 weeks succeeded in promoting the conversion of glycolytic (fast) muscle fibers to oxidative (slow) fibers, improving the energy efficiency of the muscle. This change not...

Congressman Raúl Grijalva (D-AZ) has died at the age of 77 after suffering complications with his cancer treatment. A staunch open borders advocate, Grijalva served for over 21 years in the House of Representatives and rose to become a powerful figure in the Democrat Caucus. Many other outlets also now reporting.

Greenland’s likely new prime minister on Wednesday rejected U.S. President Donald Trump’s effort to take control of the island, saying Greenlanders must be allowed to decide their own future as it moves toward independence from Denmark. Jens-Frederik Nielsen’s Demokraatit, a pro-business party that favors a slow path to independence, won a surprise victory in Tuesday’s parliamentary election, outpacing the two left-leaning parties that formed the last government. With most Greenlanders opposing Trump’s overtures, the campaign focused more on issues like healthcare and education than on geopolitics. But on Wednesday Nielsen was quick to push back against Trump, who last week...

Turmoil on Wall Street is keeping financial planners’ phones ringing as 401(k) holders watch their retirement account balances fall with the stock markets they’re tied to. For the most part, they’re being told to sit tight and breathe through it. Vanese Pitts said she watched her husband’s 401(k) shed $8,000 on Monday, when a wide-ranging market selloff pushed the S&P 500 to its lowest close since September. The sharp downturn in recent days followed several weeks of losses on Wall Street that have left the stock index about 4.8% lower than where it started the year. Many 401(k)s follow the...

Researchers have shown how a low-carbohydrate diet can worsen the DNA-damaging effects of some gut microbes to cause colorectal cancer. They found that a unique strain of E. coli bacteria, when paired with a diet low in carbs and soluble fiber, drives the growth of polyps in the colon, which can be a precursor to cancer. A low-carb diet paired with a strain of E. coli that produces the DNA-damaging compound colibactin—led to the development of colorectal cancer. The researchers found that a diet deficient in fiber increased inflammation in the gut and altered the community of microbes that typically...

CERRITOS, Calif. - Two people are behind bars after a murder shook the community of Cerritos and destroyed a family. On Feb. 25, Cuauhtémoc Garcia, known as Témo, was killed as he exercised in broad daylight on the bike path near Don Knabe Park. Garcia was a husband, a father and a businessman. What we know: After FOX 11’s Gigi Graciette first reported on the case on Friday, March 7, an anonymous FOX 11 viewer was able to identify the suspects in an unlikely place. The viewer saw a video posted to TikTok by tourists visiting from Florida. They got...

Kremlin chief Vladimir Putin is highly unlikely to embrace a United States-brokered ceasefire proposal that Ukraine has already endorsed, a former Russian diplomat warned Thursday. The Russian leader won’t see it as in his interest to accept and he will seek to bog down discussions by raising a never-ending series of modifications in order to sink it, said Boris Bondarev, who worked for the Russian permanent mission to the United Nations Office in Geneva until he resigned in opposition to Putin’s war on Ukraine. “Putin has no interest in a ceasefire,” Bondarev told POLITICO. “He thinks he can achieve his...

Drinking two small glasses of cherry juice a day may reduce gut inflammation and boost quality of life in bowel disease patients, a new study shows. The largest human trial of its kind found consuming 130ml of diluted Montmorency tart cherry juice twice a day for six weeks reduced gut inflammation markers in people with mild-to-moderate ulcerative colitis by 40%. Participants also reported a 9% improvement in health-related quality of life when taking the fruit drink supplement while receiving standard medication treatment. Montmorency tart cherries are rich in a nutrient known as anthocyanin, a natural compound that gives the fruit...

New therapies for managing aging could emerge from research into a new gene, which scientists have identified as a key driver of degeneration. Age-related diseases are strongly linked to inflammation which, when chronic, albeit low-grade, contributes to conditions such as cardiovascular disease, diabetes, neurodegeneration, and sarcopenia. In a study, Dr. Ildus Akhmetov uncovered groundbreaking insights into the role of the Ectodysplasin A2 Receptor (EDA2R) in this process. EDA2R, a member of the tumor necrosis factor receptor family, specifically binds to the EDA-A2 protein and is involved in apoptosis, or cell death, and inflammatory signaling. The team identified a striking, tissue-independent...

You can see the ridiculous political puppet show for what it really is. They are just actors reading a script.

Researchers have found that a short-term, high-caloric diet impairs brain insulin responsiveness and increases liver fat in healthy weight men, with effects extending beyond the consumption period. They also found disruptions in the brain's normal reward learning response, suggesting just five days of overeating could prime the brain for long-term unhealthy eating patterns. Twenty-nine healthy male participants aged 19–27 years (BMI 19–25 kg/m²) were assigned to either a high-caloric diet (HCD) group (n=18) or a control group (n=11). Participants in the HCD group increased their daily caloric intake by an average of 1,200 kcal during the intervention. Liver fat content...

Russia has taken back the biggest town in Kursk from Ukrainian soldiers, with President Vladimir Putin warning that Kyiv’s remaining force in the region is now trapped and must “surrender or die.” He also warned that any Ukrainian forces captured in the Russian territory would be treated as “terrorists” — not as prisoners of war — adding that “foreign mercenaries” aren’t subject to the laws of the Geneva Convention. Moscow took the town of Sudzha on Thursday and all but erased the massive gains Ukraine made during its surprise incursion last summer, whittling away at Kyiv’s largest bargaining chip in...

A United Nations judge was convicted on Thursday of trafficking a young woman to the United Kingdom and forcing her to work as a slave. Ugandan judge Lydia Mugambe, 49, "exploited and abused" the victim, prosecutors said, forcing her to work as an unpaid maid and caregiver while barring her from seeking other employment. A jury found Mugambe guilty of multiple offenses, including facilitating illegal immigration, forced labor, and witness intimidation

Staggering losses in the Battle of the Atlantic during 1942 led many U.S. Navy officials to believe that Germany’s Kriegsmarine was receiving assistance from Axis sympathizers on the U.S. East Coast and had spies in New York City. To counter this threat, the Office of Naval Intelligence’s (ONI’s) District Intelligence Office (DIO) in the Third Naval District sought assistance from an unlikely ally to help secure the waterfront: the Mob.By using informants from organized crime families, which in this time period were referred to simply as “the underworld,” the DIO was able to secure the waterfront and the coastline around...

The U.S. is poised to resume shipments to Ukraine of long-range bombs known as Ground-Launched Small Diameter Bombs (GLSDB), after they were upgraded to better counter Russian jamming, two people familiar with the weapon told Reuters. The munitions will arrive amid reports that Ukraine's supply of similarly-ranged Army Tactical Missile Systems (ATACMS) has been depleted. -snip- President Donald Trump's administration agreed on Tuesday to resume military aid and intelligence sharing with Ukraine after Kyiv said it was ready to support Washington's proposal for a 30-day ceasefire with Russia. In recent weeks, 19 GLSDBs were test-fired to assess the effectiveness of...

President Donald J. Trump is reportedly about to invoke wartime legislation to summarily deport some criminal migrants – including to Guantanamo Bay. The ‘Alien Enemies Act’ of 1798 is expected to be activated as soon as tomorrow (14). CBS News reported: “The 227-year-old law gives presidents the extraordinary power to order the arrest, detention and deportation of noncitizens who are 14 years or older and come from countries staging an ‘invasion or predatory incursion’ of the U.S. Mr. Trump is expected to cite the 18th-century statute to order the swift detention and deportation of suspected members of the Tren de...

Just hours after his inauguration on January 20, President Trump pardoned more than 1,500 people convicted of offenses related to the events of January 6, 2021. He commuted the sentences of fourteen additional people whose cases for a full pardon are still under review.

The Trump administration is placing more restrictions on Russia's oil, gas and banking sectors by further restricting Russian access to U.S. payment systems, according to four people familiar with the plans. The Treasury Department on Wednesday let lapse a 60-day exemption put in place by the Biden administration in January that allowed specific energy transactions involving sanctioned Russian banks to continue. By letting the waiver lapse, the banks may no longer access U.S. payment systems to conduct major energy transactions. The Russian financial institutions that had been exempt from sanctions included Vnesheconombank, Bank Financial Corporation Otkritie, Sovcombank, Sberbank, VTB Bank,...

Explanation: Two protostars are hidden in a single pixel near the center of a striking hourglass-shaped nebula in this near-infrared image from the James Webb Space Telescope. The actively forming star system lies in a dusty molecular cloud cataloged as Lynds 483, some 650 light-years distant toward the constellation Serpens Cauda. Responsible for the stunning bipolar outflows, the collapsing protostars have been blasting out collimated energetic jets of material over tens of thousands of years. Webb's high-resolution view shows the violence of star-formation in dramatic detail as twisting shock fronts expand and collide with slower, denser material. The premier close-up...

Almost 6 in 10 Americans who identify as Republican do not trust the Centers for Disease Control and Prevention (CDC) to provide reliable information on H5N1 bird flu, according to a new poll from health care nonprofit KFF. The CDC has confirmed 70 cases of the virus in humans since 2022, with one person dying from a severe form of the disease in January. Officials say the virus’s health risk to most people remains low, but public health researchers are concerned about the virus and its mutations About 6 in 10 adults regardless of political affiliation said they trust the...