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Inhaled nitric oxide (iNO) is associated with improvement in the mean partial pressure of oxygen (PaO2)/fraction of inspired oxygen (FiO2) ratio (P/F ratio) among patients hospitalized with COVID-19 and mild-to-moderate acute respiratory distress syndrome (ARDS), according to a study published online April 11 in Drugs in Context. Steven H. Abman, M.D. and colleagues conducted a retrospective medical chart review study that included patients who were aged 18 years or older with mild-to-moderate ARDS who received iNO for ≥24 hours continuously during hospitalization for COVID-19. The analysis included 37 patients at six sites. The researchers observed an increase in P/F ratio...

ERUSALEM, March 22 (Reuters) - Israel and New Zealand have given interim approval for the sale of biotech firm SaNOtize Research and Development's Nitric Oxide Nasal Spray (NONS) which could help prevent transmission of the COVID-19 virus, the company said on Monday. Manufacturing of NONS, under the brand name Enovid, has begun in Israel with SaNOtize's partner Nextar Chempharma Solutions Ltd and it is expected to be on sale there this summer. In New Zealand, SaNOtize has registered its nasal spray with the New Zealand Medicines and Medical Devices Safety Authority, which permits the company to distribute and sell NONS...

In ads on TV, it all looks so simple. People use mouthwash, it instantly neutralises all the nasty bacteria hiding in their mouths, and – just like that – their dental hygiene is assured. But what's really going on when you rinse a cap-load of antibacterial chemicals around your mouth? What does that to your body, and to other kinds of microorganisms that may actually be beneficial to health? As a study showed last year, the downstream effects can be surprising, and far-reaching too, affecting much more than just your dental wellbeing. In an experiment led by scientists from the...

Nitric oxide is emerging as a potential treatment for COVID-19, and doctors around the world are testing it again after it had shown to kill another coronavirus, SARS. "It's a pretty remarkable drug," Massachusetts General Hospital critical-care specialist Dr. Lorenzo Berra, who is leading a trial, told the L.A. Times. "It has a risk profile that is minimal." . . . . Dr. Berra said nitric oxide was also found to kill a coronavirus that leapt from bats to humans, University of Leuven in Belgium researchers found in 2004, according to the report. "The story ended there," Berra told the...

“It could happen in a matter of months,” says Martin Mlynczak of NASA’s Langley Research Center. ________________ “The sun is entering one of the deepest Solar Minima of the Space Age,” wrote Dr Tony Phillips just six weeks ago, on 27 Sep 2018. Sunspots have been absent for most of 2018 and Earth’s upper atmosphere is responding, says Phillips, editor of spaceweather.com. Data from NASA’s TIMED satellite show that the thermosphere (the uppermost layer of air around our planet) is cooling and shrinking, literally decreasing the radius of the atmosphere. To help track the latest developments, Martin Mlynczak of NASA’s...

Winston-Salem, N.C. – Researchers for the first time have shown that drinking beet juice can increase blood flow to the brain in older adults – a finding that could hold great potential for combating the progression of dementia. The research findings are available online in Nitric Oxide: Biology and Chemistry, the peer-reviewed journal of the Nitric Oxide Society and will be available in print soon. (Read the abstract.) "There have been several very high-profile studies showing that drinking beet juice can lower blood pressure, but we wanted to show that drinking beet juice also increases perfusion, or blood flow, to...

In the future, asthmatic children may be able to monitor their condition using breath analysing sensors built into their mobile phones. Thanks to a UK company who have embedded a carbon nanotube sensor, which can monitor nitric oxide (NO) levels in exhaled breath, into mobiles. '200 different chemicals are exhaled in your breath,' says Victor Higgs, managing director of Applied Nanodetectors, during a demonstration of his company's latest prototype at the Nano and emerging technologies forum 09 in London this week. And these can be used to monitor and diagnose a wide range of diseases.  Nanotube sensors inside mobile phones could potentially be used...