Posted on 04/03/2019 11:35:30 AM PDT by Red Badger
With its pudgy body, tired eyes and hair loss, the lower mouse could easily be the father of the sprightly and alert animal nestling alongside.
But they are actually the same age, the result of extraordinary trials of drugs which are slowing down or even reversing the ageing process.
Scientists now believe that ageing itself is responsible for many major conditions such as Alzheimer’s, Parkinson’s, arthritis, cancer, heart disease, and diabetes. And they think they have found a way to turn it off.
Anti-ageing drugs - dubbed ‘senolytics’ - are currently being trialled in humans and unlike previous tests which have focussed on a single disease, these drugs work like a broad-spectrum antibiotic, preventing or alleviating most age-related illnesses and frailty.
Scientists at The Mayo Clinic, who first coined the term senolytics, already have six trials in humans under way and plan to start six more shortly. If successful, they estimate that drugs to slow down ageing could be ready within two years.
In mice, the drugs extend lifespan by 36 per cent, the equivalent of adding around 30 years to humans, and crucially the animals remained in good health.
Clinical geriatrician Dr James Kirkland, Director of the Robert and Arlene Kogod Center on Aging at Mayo Clinic, said: “Most people don’t want to live to 130 and feel like they’re 130 but they wouldn’t mind living to 90 or 100 and feel like they’re 60. And now that can actually be achieved in animals.
“Ageing itself is the highest risk factor for most of the chronic diseases. And if you get one age-related disease, you’ve got a huge chance of having several.
“You tend to find older individuals who are completely healthy and are playing 18 rounds of golf a day, or they’ve got three,five or 10 different conditions.
(Excerpt) Read more at uk.news.yahoo.com ...
Who wants to be an old mouse, anyway?
Running through mazes.
Running from cats.
Running to eat moldy cheese.
Maybe they are only playing miniature golf. You could probably do 18 rounds of putt-putt in less than 24 hours.
Since I have no kids, there would be no one to take care of me when my retirement savings run out......
If anyone would be willing to start a GoFund me page, I would appreciate it......
It was my old buddy Jack. Jack Daniels..
And the best way to not die is to keep breathing!
Sounds like exercise and intermittent fasting really help. That is good.
I plan to live forever. So far it is working.
If I have to go, my first choice would to be hit by a liberal democrat millionaire drunk driving in his Rolls Royce, while I am in my late 90s, out for a run to unwind after several hours of passionate sex.
I don’t think that falls under their rules.
You might try running for Congress. Get tons of campaign dollars and retire a millionaire...............
18 rounds?
That would be a bit expensive................
Some people age better than others, more heredity then anything else.
I wish they had me told about this 119 years ago.
Keith Richard’s drinks, smokes and did every drug under the sun and is healthy as a horse.
Mick Jagger is a vegan health nut and is having open heart surgery today....................
You are not ready for immortality - Ambassador Kosh.
Well, yeah.
The Scifi role-playing game Traveller had a different word than “senolytics”. Their word was Anagathic. https://wiki.travellerrpg.com/Anagathic
Traveller was first published in 1977. So perhaps another case of science fiction becoming science fact?
Irony?
Proof that God luvs me then
The spice must flow.
According to the Bible, we should get at least ‘threescore and ten (70)’ years with a maximum of 120........
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