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A microbial risk score could help identify people at greater riskKey Takeaways Oral bacteria and fungi may help reshape the pancreatic microbiome and promote carcinogenesis. Earlier research has connected periodontal disease and clinical candidiasis with greater pancreatic cancer risk. Altogether, the study identified a more than threefold increase in cancer risk for every one standard deviation rise in a microbial risk score comprised of 27 bacteria and fungi. More than two dozen bacteria and fungi in the mouth may be linked to pancreatic cancer risk, according to an analysis of two large cohorts. Analysis of oral-wash samples from over 120,000...

Risk of new lesions reduced by 54% in veterans who started drug after first skin cancerKey Takeaways Nicotinamide reduced skin cancer risk by 14% overall in patients with a history of nonmelanoma skin cancer. The risk reduction increased to 54% when nicotinamide was started after a first skin cancer diagnosis. More prospective studies are needed to confirm findings and identify patients most likely to benefit. Patients with a history of using nicotinamide had a significantly lower risk of developing nonmelanoma skin cancer, particularly when starting treatment after a first skin cancer, a large retrospective cohort study showed. Overall, nicotinamide use...

Up to 10% of pediatric hematologic malignancies attributed to imaging-related radiation exposureKey Takeaways: One in 10 childhood blood cancers may result from medical imaging-associated radiation exposure. Cancer risk increased with cumulative radiation dose, ranging from 1.41 times higher to 3.59 times higher. Children exposed to at least 30 mGy had 25.6 excess blood cancers per 10,000 by age 21. One of every 10 blood cancers in children may result from radiation exposure associated with medical imaging, according to a large retrospective analysis. The risk of hematologic malignancy increased with cumulative radiation exposure versus none, ranging from 1.41 times higher for...

SHOW THIS TO PEOPLE WHO THINK CHARLIE KIRK IS RACIST. Charlie didn't even believe in race, he calls it a social construct. 0:31 VIDEO AT LINK...................

2-Year U.S. Study Shows Daily Cocoa Flavonol Supplement May Lower Inflammation In Older Adults In A Nutshell * A 2-year U.S. trial found cocoa extract lowered hsCRP, a key inflammation marker in aging. * Participants taking cocoa flavanols saw an 8.4% yearly reduction vs placebo. * Benefits were strongest in people with higher baseline inflammation. * Supplements, not ordinary chocolate, provided the tested flavanol levels. ==================================================================================== BOSTON — A daily cocoa extract supplement rich in flavanols lowered a key marker of chronic inflammation in older adults, according to a major U.S. clinical trial. The study offers rare long-term evidence that...

Bella Hadid's mother Yolanda Hadid shared a heartbreaking post for her supermodel daughter on Thursday. The Real Housewives Of Beverly Hills veteran also shared several images of Bella in a hospital getting treatment for Lyme disease. Her daughter has frequently shared details of her ongoing battle with the condition, which she's had since the age of 16.

NATIONAL CHEESEBURGER DAY National Cheeseburger Day on September 18 honors America's favorite sandwich with a slice of cheese. Let's celebrate this delicious food holiday together! #NationalCheeseburgerDay A few days ago, we celebrated National Double Cheeseburger Day. This food holiday is the lighter version. While only a single stack, this tasty burger still earns a celebration! There are many theories to the beginning of the cheeseburger dating back to the 1920s. One story suggests that Lionel Sternberger invented the cheeseburger in 1926 while working at his father’s Pasadena, California sandwich shop, The Rite Spot. During an experiment, he dropped a slice...

Marketed as a natural wellness product and widely available, 7-OH seemed like a viable alternative for Hayden resident Kevin McAuliffe to use as an energy and mood booster. However, McAuliffe said it became “absolutely impossible for me to ween off 7-OH because basically I became highly addicted to it, and I was waking up in the middle of night with withdrawal symptoms.” “I was having extreme health side effects,” McAuliffe said of the product 7-Hydroxymitragynine, known as 7-OH, which is a chemically concentrated derivative of the kratom plant. Addiction treatment professionals, UCHealth physicians, valley residents and the U.S. Food and...

A study reports that acute normovolemic hemodilution (ANH)—a blood-saving method in which a patient's blood is collected before going on heart-lung bypass and reinfused near the end of cardiac surgery—remains underused in the United States at 14.7%. Yet the study found that ANH lowered the likelihood of a transfusion by 27%, a decrease in blood use that could cut costs substantially while still protecting patient safety and outcomes. Global demand for cardiac surgery is increasing, with more than 1 million procedures performed annually worldwide. In high-income countries like the United States, cardiac surgery remains the largest consumer of blood products,...

Methotrexate, a common medication used to treat rheumatoid arthritis, has a newly recognized useful secondary effect of lowering blood pressure and potentially reduces the risk of heart disease in people with this condition. A new study led by researchers, has shown that methotrexate significantly lowers blood pressure when compared to another arthritis drug, sulfasalazine, marking the first clear evidence of this effect in newly diagnosed patients. Occurring in about 1 in 100 people, rheumatoid arthritis (RA) is a common autoimmune disease which leads to inflammation and pain in the connective tissue of a patient's joints. Over six months, the researchers...

In a new study, researchers discovered that zeaxanthin, a plant-derived carotenoid best known for protecting vision, may also act as an immune-boosting compound by strengthening the cancer-fighting activity of immune cells. The findings highlight the potential of zeaxanthin as a widely available supplement to improve the effectiveness of cancer immunotherapies. The study builds on years of work by Chen's lab to better understand how nutrients influence the immune system. By screening a large blood nutrient library, the team identified zeaxanthin as a compound that directly enhances the activity of CD8+ T cells, a crucial type of immune cell that kills...

A comprehensive analysis of nearly 29,000 patients with coronary artery disease (CAD) suggests that clopidogrel, a commonly prescribed blood thinner, is more effective than aspirin in preventing serious heart and stroke events, without increasing the risk of major bleeding. The new study challenges the long-standing recommendation of aspirin as the default treatment for secondary prevention in CAD patients. CAD, a condition characterized by narrowed heart arteries, often requires lifelong treatment to prevent heart attacks, strokes, and cardiovascular death. Aspirin has traditionally been prescribed indefinitely for patients with CAD. However, the evidence supporting aspirin's long-term benefits and safety has been limited....

Dual antiplatelet therapy after cardiac bypass surgery is no more effective than acetylsalicylic acid alone and also increases the risk of serious bleeding. This is shown in a study by researchers. Today, dual antiplatelet therapy is recommended in international treatment guidelines after heart bypass surgery for acute coronary artery disease. The current study compares two different antithrombotic, i.e., blood-thinning, treatments. One is single antiplatelet therapy with acetylsalicylic acid (Aspirin) alone, the other is dual antiplatelet therapy with acetylsalicylic acid and ticagrelor (Brilique). "There is no doubt that this patient group needs antiplatelet therapy. However, it has so far been unclear...

Discontinuing oral anticoagulation (OAC) therapy resulted in a lower risk of a composite of stroke, systemic embolism or major bleeding than continuing OAC therapy in patients who had successful ablation for atrial fibrillation at least 12 months previously, according to results from a late-breaking trial. Atrial fibrillation (AF) is a common type of arrhythmia characterized by an abnormal irregular heartbeat that can increase the risk of stroke and thromboembolism (blood clots). Ablation can be used to destroy small sections of heart tissue that may be causing abnormal heartbeats. Oral anticoagulation (OAC) is recommended in all patients for at least two...

The widely used diabetes drug metformin changes blood metal levels in humans. The study is an important step in understanding the drug's many actions and designing better ones in the future. Metformin is the most widely prescribed diabetes drug in the world. Apart from lowering blood sugar levels, it is also known to have a broad range of beneficial side effects such as against tumors, inflammation and atherosclerosis. However, although it has been used for more than 60 years now, its mechanism of action is still not clear, hampering the development of even better drugs against these conditions. Ogawa Wataru...

Beta blockers—drugs commonly prescribed for a range of cardiac conditions, including heart attacks—provide no clinical benefit for patients who have had an uncomplicated myocardial infarction with preserved heart function. Beta blockers have been the standard treatment for these patients for 40 years. This is a breakthrough discovery from the "REBOOT Trial." Additionally, a REBOOT substudy, shows that women treated with beta blockers had a higher risk of death, heart attack, or hospitalization for heart failure compared to women not receiving the drug. Men did not have this increased risk. Says Borja Ibáñez, MD.l, "Currently, more than 80% of patients with...

The gut contains the largest collection of immune cells in the body. New research shows that some of those immune cells travel along the brain/gut axis in a mouse model of Alzheimer's disease (AD), providing a potential new therapeutic pathway for the memory-robbing malady. The research also shows that feeding the mice a high-fiber diet reduces AD-related frailty, including tremor. Priya Makhijani, Ph.D. found that specific antibody-producing B cells, normally responsible for keeping the microbiome and the gut immune system in harmony, were reduced in the mice bred to develop AD. She also discovered this cell type has a migratory...

Jerry Greenfield, co-founder of Ben & Jerry's, has resigned because the company they sold to back in 2000, Unilever, doesn't want them to be woke anymore. I have to give you the full text because it's hilarious. Grab your popcorn. It's with a broken heart that l've decided I can no longer, in good conscience, and after 47 years, remain an employee of Ben & Jerry's. I am resigning from the company Ben and I started back in 1978. This is one of the hardest and most painful decisions l've ever made. This isn't because l've lost my love for...

A daily dose of vitamin D could help combat ageing, according to a recent study.It found that taking vitamin D supplements for four years managed to prevent three years’ worth of ageing. Previous studies have hinted that vitamin D supplements can help combat some of the biggest signs of ageing, which are linked to many age-related diseases such as cancer, heart disease and dementia. To put this theory to the test, researchers from Mass General Brigham and the Medical College of Georgia studied the results of a previous trial. That experiment enlisted thousands of women over 55 and men over...

Despite being a staple food for millions of people worldwide, the genetic secrets of the sweet potato have long remained a mystery to scientists. That is, until now. New research has revealed the complexities behind the genetic makeup of these tubers, widely considered to be a superfood for their health benefits. What science reveals about them is surprising, revealing a previously unknown evolutionary history involving a “hybrid ancestry” behind the beloved vegetables. The research, led by Professor Zhangjun Fei at the Boyce Thompson Institute, was recently published in Nature Plants. The Hybrid Ancestry of Sweet Potatoes Sweet potatoes carry six...