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A new discovery reveals that vitamin C may help protect reproductive health from a harmful environmental chemical. Using a fish model, researchers found that exposure to potassium perchlorate, a chemical commonly used in explosives and fireworks, can harm sperm production, potentially reducing fertility. Led by Ramji Bhandari, the team used Japanese rice fish, called medaka, to investigate how the chemical affects reproductive health. Researchers found that male fish exposed to potassium perchlorate alone experienced a dramatic drop in fertility and clear damage to their testes. But fish exposed to vitamin C and the chemical at the same time showed improved...

A research team has demonstrated for the first time in non-human primates that auditory stimulation at 40 Hz significantly elevates β-amyloid levels in the cerebrospinal fluid (CSF) of aged rhesus monkeys, with this effect persisting for over five weeks. The study provides the first non-human primate experimental evidence supporting the use of 40-Hz stimulation as a noninvasive physical therapy for Alzheimer's disease (AD), revealing significant differences between primate and rodent models. Researchers conducted the study using nine aged rhesus macaques (Macaca mulatta) aged 26–31 years. These aged individuals developed widespread spontaneous amyloid plaques in their brains, effectively mimicking the Aβ...

Triple-negative breast cancer (TNBC) is among the most aggressive types of breast cancer. Despite initial responsiveness, many patients experience rapid relapse driven by cancer stem-like cells that survive chemotherapy and seed metastasis. Addressing this unmet need, researchers have discovered that pitavastatin, a widely prescribed cholesterol-lowering drug, can directly inhibit the anti-apoptotic protein Mcl-1, a key driver of survival, stemness, and paclitaxel resistance in TNBC cells, thereby preventing distant metastasis. The team found that pitavastatin binds specifically to the BH3-binding groove of Mcl-1, disrupting its stability and inducing mitochondrial dysfunction. This inhibition triggered a cascade of mitochondrial damage, leading to ROS...

A novel tumor suppressor, BATF2, can be silenced by factors in the tumor microenvironment, leading to a reduced immune response in five preclinical models of head and neck cancer, according to researchers. The results demonstrate that glutamine in the tumor microenvironment can cause epigenetic silencing of BATF2, which affects the STING signaling pathway and overall immune response. Lei said, "This study characterizes a novel oral cancer tumor suppressor that drives immune surveillance but is inhibited by high levels of glutamine." BATF2 is a tumor suppressor involved in regulating immune responses, helping to maintain anti-tumor immune surveillance. BATF2 is highly expressed...

Simple pharmaceutical interventions could help older brains cope with memory impairment and recovery after surgery, new studies in mice suggest. The first paper examined the problem of post-surgical cognitive impairment. Immediately after surgery, cognitive impairment is common, but studies have found that 10% of adults over the age of 60 still have deficits to learning, memory and executive function three months after surgery, Rudolph said. Propofol is a common anesthetic agent that has shown promise in other mouse studies for improving cognition in Alzheimer's disease models, though in high doses it may harm the brain, Rudolph said. To study whether...

Researchers recently carried out a study involving mice, exploring the possibility that the exposure to bright lights also influences eating behavior and body weight. "Environmental light regulates nonimage-forming functions like feeding, and bright light therapy shows anti-obesity potential, yet its neural basis remains unclear," wrote Wen Li. "We show that bright light treatment effectively reduces food intake and mitigates weight gain in mice through a visual circuit involving the lateral hypothalamic area (LHA)." Light is known to play a crucial role in various physiological processes, including sleep, the release of hormones and eating patterns. Bright light therapy (BLT), which entails...

People who stop taking weight-loss injections such as Wegovy and Mounjaro regain pounds much faster than those who halt exercising and dieting, a new medical study shows. Research published in The British Medical Journal this month suggests that people lose around a fifth of their body weight when taking the jabs. But once they quit them, they regain 0.8 kg per month on average, meaning they return to their pre-treatment weight in around a year-and-a-half, according to the findings. The study was based on the analysis of more than 9,000 adults worldwide taking weight management medications (WMMs). Novo Nordisk, the...

Alex Berenson, author of Tell Your Children: The Truth About Marijuana, Mental Illness, and Violence, pointed out that the New York Times had curiously removed from an article about the Uvalde school shooter a former coworker’s recollection that he complained about his grandmother not letting him smoke weed. The Times didn’t append a correction to the story as it might be expected to do when fixing a factual inaccuracy... Assuming the elided detail was accurate, it would fit a pattern. Mass shooters at Rep. Gabby Giffords’s constituent meeting in Tucson, Ariz. (2011), a movie theater in Aurora, Colo. (2012), the...

Something very sinister is happening at the supposed happiest place on Earth. A dead body was just discovered at Disney World and it’s the sixth one in just three months. It’s an obvious public relations disaster for Disney but it also raises all kinds of questions. What are the odds of so many people turning up dead in one place, even if the deaths are unrelated? Breitbart News reports: Sixth Dead Body Found at Disney World in Less than Three Months A sixth person has died at Disney World in less than three months. The body was found just one...

RFK's new initiative is looking to take aim at all the junk: Rest in peace, food pyramid! Long live the Trump Triangle of health! And with health advice like this, long life is much more likely. The new website to promote the Trump dietary guidelines is realfood.gov! And, if you'll notice, it's essentially the inverse of the old food pyramid, pictured here 👇 Wikipedia/USDA Protein, dairy, and fat are now at the top of the graphic. Here's RFK promoting the real food campaign and attacking the ultra-processed food industry at today's dietary guideline announcement: The hard truth is that our...

An apparently homeless thief was electrocuted to death while trying to steal copper wiring from a California construction site — as power was knocked out to 2,500 homes, reports said. The unidentified man was killed Sunday in a vacant strip mall that’s in the process of being demolished, with witnesses saying they heard a loud explosion at around 2 p.m. before electricity went out for several hours, police told CBS News. The explosion is believed to be a transformer that blew up, knocking out power for several hours, Pomona police said. One neighbor rushed to the scene where a woman...

Intestinal parasites are my companion in Costa Rica. Every six months or so I make a trip to the pharmacy and ask for pastillas antiparasiticos. The most common over-the-counter pill is the anti-protozoal agent Nitazoxanide: two pills a day for three days to treat an array of intestinal parasites. The pills scour your digestive system, wiping out nematodes, cestodes, and helminths, as well as various protozoa with exotic names such as Cryptosporidium parvum, Giardia lamblia, and Entamoeba histolytica. My body always lets me know when it is time for a treatment. The first sign is a growling stomach within a...

News outlets report a Canadian woman is seeking assisted suicide after being unable to receive the medical treatment she desperately needs for eight years. Jolene Van Alstine from Saskatchewan was diagnosed with a rare condition called normocalcemic primary hyperparathyroidism that causes severe bone pain, nausea, and vomiting. Despite undergoing three surgeries, she still needs specialized care to locate and remove an overactive parathyroid gland. However, no surgeon is available in her province to perform the procedure, and she cannot get a referral to see specialists outside Saskatchewan. After going without proper treatment for so long, Van Alstine applied for Canada’s...

Here we go again. Yet another violent transgender creep has been arrested for political violence. There’s a definite pattern here, and the left and their media buddies keep pretending it doesn’t exist. Think about it, these incidents involve a very small group of mentally ill people, yet they are stacking up violent and even deadly attacks month after month, and nobody on the left wants to talk about it. The fake news would rather lecture about pronouns than talk about hammers, broken glass, bullets flying, and right-wing politicians being targeted. Meanwhile, the media and the left are still pushing the...

ATOKA, Tenn. - A tiny and innocent life was saved recently, thanks to a box outside a Mid-South fire station and a parent who decided to use it. Fire officials said that someone over the weekend surrendered an infant at a Safe Haven Baby Box at Atoka Fire Station No. 1 in the Tennessee town about 25 miles northeast of Memphis. The boxes allow mothers of newborns to safely and legally give away their babies without being prosecuted. "What happened over the course of this weekend is exactly why we have this box," Atoka Fire Chief Bill Scott said. "It...

The State of Colorado must pay $5.4 million in attorneys’ fees to Becket following the state’s unconstitutional effort to outlaw abortion pill reversal. Becket represented Bella Health and Wellness, a Denver-area Catholic pro-life healthcare clinic, defending them against Colorado’s attempt to make it illegal for doctors and nurses to help women who take the first abortion pill but then decide to continue their pregnancies. A federal court found that Colorado’s attempt to ban abortion pill reversal violated the First Amendment. A federal law now requires the state to pay attorneys’ fees and court costs. “At least 18 moms who received...

The restaurant industry is trying to figure out whether America has hit peak pizza. Once the second-most common U.S. restaurant type, pizzerias are now outnumbered by coffee shops and Mexican food eateries, according to industry data. Sales growth at pizza restaurants has lagged behind the broader fast-food market for years, and the outlook ahead isn’t much brighter. “Pizza is disrupted right now,” Ravi Thanawala, chief financial officer and North America president at Papa John’s International, said in an interview. “That’s what the consumer tells us.” The parent of the Pieology Pizzeria chain filed for chapter 11 bankruptcy protection in December....

After more than 10 years of partnering on search and rescue missions, wildfire fights and medical interventions, Bernalillo County firefighters have been ousted from the Sheriff's Office's helicopter unit. The reason? A policy change allowing firefighters to smoke marijuana while off duty. "Sheriff John Allen made this decision in early June 2025 following a county policy change that allows firefighters to use marijuana off-duty and removes random cannabis testing," Jayme Gonzales, Bernalillo County Sheriff's Office spokesperson, said in a news release Wednesday. "MASU (Metro Air Support Unit) performs aviation operations and life-saving rescue work where the margin for error is...

Top leaders in the space, from Microsoft to OpenAI, are pouring millions of dollars into schools, colleges, and universities, often providing students with access to their AI products. The justification, touted in a fresh New York Times piece by both by tech companies and the educators receiving the funding, is that the tools will accelerate learning and prepare students for a world driven by AI. But...Some research suggests that AI actually inhibits learning, with one notable study conducted by researchers from Microsoft and Carnegie Mellon finding that it atrophies critical thinking skills.Even more urgently, the safety of AI chatbots is...

In July, researchers using the NASA-funded Asteroid Terrestrial-impact Last Alert System survey telescope in Chile made an exceedingly rare discovery: a mysterious object passing through the solar system at far too high a speed to be bound by the Sun’s gravity. As the visitor made its closest approach to Earth, coming within just 167 million miles on December 19, an international team of researchers from the alien-hunting astronomy project Breakthrough Listen pointed the Green Bank Telescope — the largest single-dish radio telescope in the world — at 3I/ATLAS. In a yet-to-be-peer-reviewed paper, they revealed sobering — albeit probably expected —...