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Keyword: alzheimers

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  • Study shows vicious cycle of protein clumping in Alzheimer's disease and normal aging (Urolithin A addresses mitochondrial dysfunction)

    05/24/2024 9:40:41 AM PDT · by ConservativeMind · 9 replies
    It has long been known that a hallmark of Alzheimer's disease, and most other neurodegenerative diseases, is the clumping together of insoluble protein aggregates in the brain. During normal disease-free aging, there is also an accumulation of insoluble proteins. Researchers have recently completed a systematic study in worms that paints an intricate picture of the connections between insoluble proteins in neurodegenerative diseases and aging. Furthermore, the work demonstrated an intervention that could reverse the toxic effects of the aggregates by boosting mitochondrial health. "Our study shows how maintaining healthy mitochondria can combat protein clumping linked to both aging and Alzheimer's,"...
  • "Keeps Falling" - The Ballad of Joe Biden

    05/18/2024 6:47:16 AM PDT · by Dr. Marten · 9 replies
    Rumble ^ | 05.16.2024 | Jimmy Failla
    "Keeps Falling" - The Ballad of Joe Biden
  • Biden mocked over number of jump cuts in Trump debate challenge video: ‘Like a Claymation film’

    05/15/2024 2:17:17 PM PDT · by lowbridge · 153 replies ^ | May 15, 2024 | Ryan King
    President Biden was mocked by critics Wednesday over the number of jump cuts in his 14-second debate challenge to Donald Trump — with one wag on Twitter likening the brief video to “a Claymation film.” The video of Biden, 81, was released at 8 a.m. and featured the incumbent taunting the former president to “make my day” by agreeing to a on-one-on debate. “In a super short 14 second video, the Biden campaign needed to do 5 jump cuts because Crooked Joe couldn’t deliver a clean reading. Total disaster,” Trump campaign official Steven Cheung posted on X. “Biden’s video has...
  • Organ transplant drug may slow Alzheimer's disease progression (Rapamycin (Rapamune) helped regulate neurons)

    05/04/2024 12:51:35 PM PDT · by ConservativeMind · 7 replies
    Protein imbalances that increase brain cell excitability may explain why individuals with Alzheimer's disease (AD) who also experience seizures demonstrate more rapid cognitive decline than those who do not experience seizures. These imbalances may be present in the brains of individuals before the onset of AD symptoms. The team found that an existing drug called rapamycin, initially developed as an immunosuppressant for organ transplant patients that suppresses signaling between neurons, was able to regulate the over-excited neurons in mouse models of AD and seizures, and preserve cognitive function, like memory and the ability to learn new things. "Experts used to...
  • Biden mocked for shuffling around White House lawn with dazed look during Japanese PM ceremony

    04/10/2024 12:53:11 PM PDT · by ChicagoConservative27 · 25 replies
    NY Post ^ | 04/10/2024 | Ryan King
    President Biden raised eyebrows Wednesday morning, when he appeared disoriented while welcoming Japanese Prime Minister Fumio Kishida to the White House for a state visit. Biden, 81, and Kishida, 66, greeted one another before shaking the hands of members of both the US and Japanese delegations on the South Lawn. The leaders then mounted a stage for the national anthems of both countries, before reviewing US military honor guards. Ahead of the review, Biden and Kishida were greeted with a salute by a military aide.
  • Joe Biden Shamelessly Invokes Beau Biden During Key Bridge Visit

    04/06/2024 11:04:38 AM PDT · by Sam77 · 56 replies
    PJ Media ^ | 6 April 2024 | MATT MARGOLIS
    On Friday, Joe Biden visited the site of the collapsed Francis Scott Key Bridge in Maryland — the same bridge he claimed he commuted over regularly via rail, even though it has no tracks — and he just couldn't help himself by invoking the death of his son Beau in order to play the empathy card. "Well, to all the families and loved ones who are grieving: I’ve come here to grieve with you. We all are," he said. "It’s not the same, but I know a little bit about what it’s like to lose a piece of your soul...
  • How diabetes might lead to Alzheimer's: Study suggests the liver is key

    04/04/2024 9:32:50 PM PDT · by ConservativeMind · 16 replies
    New research conducted in mice offers insights into what's going on at the molecular level that could cause people with diabetes to develop Alzheimer's disease. The study adds to a growing body of research on the links between type 2 diabetes and Alzheimer's disease, which some scientists have called "type 3 diabetes." The findings suggest that it should be possible to reduce the risk of Alzheimer's by keeping diabetes well controlled or avoiding it in the first place, according to researchers. Narendra Kumar led the study. "We think that diabetes and Alzheimer's disease are strongly linked," Kumar said, "and by...
  • Fiber supplements could improve brain function in seniors, study says (“Significant improvement”)

    03/29/2024 6:54:28 PM PDT · by ConservativeMind · 20 replies
    Medical Xpress / Atlanta Journal-Constitution / Nature Communications ^ | March 23, 2024 | Ebony Williams / Mary Ni Lochlainn et al
    Fiber is essential for the digestive system. It helps maintain a healthy weight and lowers the risk of diabetes, heart disease and certain cancers. Getting the right amount of fiber, whether through food or drinks, is a great way to relieve constipation. In addition to all that, fiber supplements could improve brain function in older adults, according to a new study. The study followed individuals over the age of 60 for a 12-week period. Results found those who took prebiotic fiber supplements showed a "significant improvement in memory." The study evaluated the gut microbiome and its correlation with both cognitive...
  • Keto diet found to slow early stages of Alzheimer's disease in mice (Beta-hydroxybutyrate helps)

    03/29/2024 8:12:50 PM PDT · by ConservativeMind · 14 replies
    Medical Xpress / UC Davis / Communications Biology ^ | March 19, 2024 | Amy Quinton / Jacopo Di Lucente et al
    A new study shows that a ketogenic diet significantly delays the early stages of Alzheimer's-related memory loss in mice. This early memory loss is comparable to mild cognitive impairment in humans that precedes full-blown Alzheimer's disease. The ketogenic diet is a low-carbohydrate, high-fat, and moderate-protein diet, which shifts the body's metabolism from using glucose as the main fuel source to burning fat and producing ketones for energy. Researchers previously found that mice lived 13% longer on ketogenic diets. The new study, which follows up on that research, found that the molecule beta-hydroxybutyrate, or BHB, plays a pivotal role in preventing...
  • Viagra Could Be Good for Your Brain

    03/17/2024 6:50:09 PM PDT · by Fractal Trader · 60 replies
    Wall Street Journal ^ | 17 March 2024 | Allysia Finley
    Can Viagra prevent or reverse Alzheimer’s disease? Older men’s ship may be coming in. New research from the Cleveland Clinic suggests the erectile-dysfunction drug could ward off cognitive decline, illustrating how artificial intelligence can help scientists repurpose old medications for new diseases. The study, published this month in the Journal of Alzheimer’s Disease, builds on earlier research by the Cleveland Clinic that identified sildenafil, the generic name for Viagra, as a promising Alzheimer’s treatment. Researchers first identified genes associated with the disease’s pathology, amyloid plaque and tau tangles in the brain. They then mapped out the molecular interplay among more...
  • How 40Hz sensory gamma rhythm stimulation clears amyloid in Alzheimer's mice (Pulsing light and sound do clear brain waste)

    03/04/2024 11:09:43 AM PST · by ConservativeMind · 34 replies
    Studies are producing mounting evidence that light flickering and sound clicking at the gamma brain rhythm frequency of 40 Hz can reduce Alzheimer's disease (AD) progression and treat symptoms in human volunteers as well as lab mice. In a mouse model, researchers reveal a key mechanism that may contribute to these beneficial effects: clearance of amyloid proteins, a hallmark of AD pathology, via the brain's glymphatic system, a recently discovered "plumbing" network. The paper describes a series of experiments showing that when sensory gamma stimulation increases 40 Hz power and synchrony in the brains of mice, that prompts a particular...
  • Fox News host links Biden's love of ice cream to Alzheimer's disease: 'You see what's going on here?'

    02/27/2024 7:21:55 PM PST · by NetAddicted · 60 replies
    Mediaite ^ | 2/27/2024 | Michael Luciano
    Fox News host Jesse Watters criticized President Joe Biden and his affinity for ice cream on Tuesday after the president was seen in a New York ice cream parlor the day before. Ahead of Monday’s airing of Late Night with Seth Meyers, on which Biden was a guest, the president patronized a shop with Meyers and told reporters he hopes there will be a ceasefire in Gaza “by next Monday” as Israel continues its invasion and bombing campaign in the territory after the Oct. 7 attacks. The right has fixated on Biden’s famous hankering for ice cream, with some suggesting...
  • Yoga provides unique cognitive benefits to older women at risk of Alzheimer's disease, study finds (Kundalini yoga)

    02/27/2024 10:01:38 AM PST · by ConservativeMind · 20 replies
    A new study found Kundalini yoga provided several benefits to cognition and memory for older women at risk of developing Alzheimer's disease, including restoring neural pathways, preventing brain matter decline, and reversing aging and inflammation-associated biomarkers—improvements not seen in a group who received standard memory training exercises. In the study, a group of more than 60 women ages 50 and older who had self-reported memory issues and cerebrovascular risk factors were recruited from a UCLA cardiology clinic. The women were divided evenly. The first group participated in weekly Kundalini yoga sessions for 12 weeks, while the other group underwent weekly...
  • Is The 100-Year Old TB Vaccine a New Weapon Against Alzheimer’s?

    02/25/2024 1:10:48 PM PST · by nickcarraway · 19 replies
    The Guardian ^ | Sun 25 Feb 2024 | David Robson
    Studies suggest the BCG jab discovered a century ago could provide a cheap and effective way of boosting the immune system to protect people from developing the conditionScientific discoveries can emerge from the strangest places. In early 1900s France, the doctor Albert Calmette and the veterinarian Camille Guérin aimed to discover how bovine tuberculosis was transmitted. To do so, they first had to find a way of cultivating the bacteria. Sliced potatoes – cooked with ox bile and glycerine – proved to be the perfect medium. As the bacteria grew, however, Calmette and Guérin were surprised to find that each...

    12/25/2023 3:09:32 PM PST · by AnthonySoprano · 10 replies
    Parody Whitney via YT ^ | 12/25/2023 | Parody Whitney
    FROSTY THE SLOW MAN See Link in main Post
  • What you eat every day may dictate your Alzheimer’s disease risk

    12/06/2023 5:41:45 AM PST · by logi_cal869 · 19 replies
    Study Finds ^ | 12/5/2023 | John Andere
    The right diet can help stave off dementia, according to new collaborative research. Even better, the report even tells us which foods we should include with breakfast, lunch, and dinner to best support the brain. The new study concludes that diets emphasizing plants, such as the Mediterranean diet or traditional diets seen in China, Japan, and India, appear to reduce Alzheimer’s disease risk, especially when compared to a fattier, more processed Western diet. In this article we’ll share the important findings of this study, and include a table of the suggested foods (and their anti-Alzheimer’s properties) to help ward off...
  • Alzheimer's research: New study uncovers previously unknown processes in fat metabolism (Vitamin K can help)

    12/03/2023 8:58:43 PM PST · by ConservativeMind · 16 replies
    Medical Xpres / Universität des Saarlandes / Cell Chemical Biology ^ | Nov. 28, 2023 | Claudia Ehrlich / Valerie Christin Zimmer et al
    New insights into the pathogenesis of Alzheimer's disease could unlock novel therapeutic approaches and help to prevent the disease. A study has shed light on a bidirectional interaction in the body's fat metabolism that could play an important role in the development of the disease. Dietary and other lifestyle factors such as smoking also play a role. One protein that is known to play a key role in Alzheimer's disease is the amyloid-beta peptide. "This small amyloid-beta protein accumulates in the form of hardened plaques within a patient's brain. Amyloid-beta is a key element in the development of Alzheimer's and...
  • Obesity linked to neurodegeneration through insulin resistance

    11/12/2023 9:09:10 AM PST · by ConservativeMind · 16 replies
    Medical Xpress / Public Library of Science / PLoS Biology ^ | Nov. 7, 2023 | Alassaf M, Rajan A et al
    Researchers have discovered a link between obesity and neurodegenerative disorders like Alzheimer's disease. Using the fruit fly, the research shows that a high-sugar diet—a hallmark of obesity—causes insulin resistance in the brain, which in turn reduces the ability to remove neuronal debris, thus increasing the risk of neurodegeneration. Although obesity is known to be a risk factor for neurodegenerative disorders like Alzheimer's disease and Parkinson's disease, exactly how one leads to the other remains a mystery. The study focused on this by taking advantage of the similarity between humans and fruit flies. Having previously shown that a high-sugar diet leads...
  • Biden Has Been Channeling Ronald Reagan All Week

    10/23/2023 9:39:51 AM PDT · by ChicagoConservative27 · 21 replies
    thedailybeast ^ | 10/21/2023 | Matt Lewis
    I never thought the day would come when I, a die-hard Reagan Republican, would credit a Democratic president for being Reaganesque. Amazingly, it has. Don’t look now, but Joe Biden has been leading with moral authority in the struggle against violent authoritarianism and illiberalism at home and abroad. While Donald Trump criticized the prime minister of Israel, Benjamin Netanyahu, Biden met with Bibi and declared America’s support for Israel to be “rock solid and unwavering.” And while Republican support for providing U.S. aid to Ukraine has eroded, Biden has steadfastly supported them in their plight against a brutal Russian invasion.
  • $500m Alzheimer's drug scandal: NY scientist behind NIH-funded therapy busted for allegedly manipulating data in 20 research papers - now there are calls for trials to be cut off

    10/16/2023 6:18:16 PM PDT · by Libloather · 28 replies
    Daily Mail ^ | 10/16/23 | Caitlin Tilley
    Scientists are calling for stage 3 clinical trials of an Alzheimer's drug to be scrapped after a report highlighted serious doubts about the legitimacy of research that helped the medicine reach that stage. A long-awaited report by the City University of New York (CUNY) accused one of its faculty members, neuroscientist Hoau-Yan Wang, of egregious misconduct concerning 20 research papers — defined as workplace behavior so outrageous, dangerous, or illegal that an employer cannot reasonably expect to correct it through progressive discipline. According to the 50-page document obtained by Science, Mr Wang could not provide original data to disprove allegations...