Keyword: alzheimers
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Used my Linux Mint 20 Pc to post some text the other day and it disappeared. That supports the theory that it was not just a Windows 11 problem. Rather than wasting any more time with disappearing text, I'm going to retire from Free Republic. RIP.
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Chlamydia pneumoniae—a common bacterium that causes pneumonia and sinus infections—can linger in the eye and brain for years and may aggravate Alzheimer's disease, according to a study. The discovery suggests this bacterium can amplify Alzheimer's disease and points to potential interventions including inflammation-limiting therapies and early antibiotic treatment. The study shows for the first time that Chlamydia pneumoniae can reach the retina—the tissue lining the back of the eye—where it triggers immune responses linked to inflammation, nerve cell death and cognitive decline. "Seeing Chlamydia pneumoniae consistently across human tissues, cell cultures and animal models allowed us to identify a previously...
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The president told 'New York' magazine he feels "the same as I did 40 years ago" in a new interview about his aging“I hate to waste a lot of time on this, but if you’re going to write a bad story about my health, I’m going to sue the ass off of New York magazine," he said. "There will be a time when you can write that story, maybe in two years, three years, five years — five years, no one is going to care, I guess. Go ahead and sit down.” Speculation about Trump's health has run rampant in...
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Does this look legit? Alzheimer's Reversal??? +++++++++ WHAT'S WRONG: Your family member has Alzheimer's disease. This is a brain sickness that makes people forget things and get confused. It happens because parts of the brain stop working right. THE GOOD NEWS: +++++++++ Scientists just found new ways to help fix the brain. We now have a plan that uses three different medicines that work together to help the brain get better. HOW THE TREATMENT WORKS: +++++++++ Think of the brain like a house with three problems: PROBLEM 1: The lights are dim The brain cells don't have enough energy Medicine...
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Furious over the killing of a U.S. citizen at the hands of an ICE agent in Minneapolis, former Minnesota Gov. Jesse Ventura slammed President Donald Trump as a “draft-dodging coward” who has “destroyed the Constitution.” Ventura, an independent, former wrestler and Vietnam veteran, was at his high school alma mater Thursday to show support for it after ICE descended on the school the same day Renee Nicole Good was killed by an ICE agent. “He’s the draft dodging coward, who when it was his time to serve his country, he did what all rich white boys did. I wasn’t a...
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A research team has demonstrated for the first time in non-human primates that auditory stimulation at 40 Hz significantly elevates β-amyloid levels in the cerebrospinal fluid (CSF) of aged rhesus monkeys, with this effect persisting for over five weeks. The study provides the first non-human primate experimental evidence supporting the use of 40-Hz stimulation as a noninvasive physical therapy for Alzheimer's disease (AD), revealing significant differences between primate and rodent models. Researchers conducted the study using nine aged rhesus macaques (Macaca mulatta) aged 26–31 years. These aged individuals developed widespread spontaneous amyloid plaques in their brains, effectively mimicking the Aβ...
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Lab-dish study using brain cells from elderly mice yields promising results for a potential anti-aging recipe, but more research is necessary. In A Nutshell * Aging brain cells in mice restored youthful energy balance (GTP levels) within 16 hours using vitamin B3 and green tea extract * The treatment cleared toxic protein buildup and improved survival by 22% in Alzheimer’s-model neurons * It also restored waste-clearing vesicle function by reducing the buildup of Rab7- and Arl8b-tagged vesicles * Findings are based on in vitro studies and will require confirmation in living animals and humans ================================================================================= IRVINE, Calif. — Can brain...
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Scientists are working to understand how aging itself can be modified to prevent age-related diseases, including Alzheimer's disease. A new study has discovered that calcium alpha-ketoglutarate (CaAKG), a safe, naturally occurring metabolite commonly studied for healthy aging, can restore key memory-related brain functions that have been disrupted in Alzheimer's disease. The main aim of the study was to evaluate whether CaAKG could also enhance synaptic plasticity in the Alzheimer's brain, restore memory-related signaling, protect neurons from early degenerative changes, and contribute to healthier cognitive aging. The study shows that CaAKG helps brain cells communicate better in Alzheimer's disease models. It...
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Scientists have reversed Alzheimer’s disease in mice, potentially showing a pathway to treat the illness among humans, according to a Dec. 22 peer-reviewed study published in the Cell Reports Medicine journal.Alzheimer’s is traditionally considered irreversible. In the study, researchers treated two groups of mice with P7C3-A20, a pharmacologic agent. One group carried human mutations related to amyloid processing, while the other carried a tau protein mutation. Both amyloid and tau pathologies are two major early events of Alzheimer’s. Researchers say that as mice develop brain pathologies resembling Alzheimer’s, they are ideal subjects to test how P7C3-A20 affects Alzheimer’s in humans....
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A paper published today in the journal Cell Reports Medicine offers new hope for an Alzheimer’s drug that doesn’t just slow cognitive decline but may reverse it. The study, by researchers at the University of Colorado Anschutz, found that Leukine or GM-CSF, a drug long-approved to treat other conditions, was able to stop brain cells from dying in Alzheimer’s patients when measured in a blood test. Brain cell death is a hallmark of Alzheimer’s disease. “The main thing that we found…is that the people who were treated with Leukine or GM-CSF actually lost the ability to kill their nerve cells…to...
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The founder of Dignitas – a Zurich, Switzerland, clinic that assists those with illnesses end their lives – says he wants to open a chain of "suicide clinics" in other countries to give everyone, including the mentally ill, the "the choice of a choice." Ludwig Minelli Ludwig Minelli, a Swiss lawyer, told the London Sunday Times he has already opened an associated Dignitas office in Germany and he intends to lift the "taboo" against suicide by lobbying other countries to set up clinics to offer information on effective methods of suicide and to alert people to the risks of...
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Alzheimer's disease (AD), the leading cause of dementia, affects nearly 40 million individuals globally. Despite extensive research over the past decades, no treatments have been found that can halt or reverse the progression of this devastating disease. In AD, a major contributor to neuronal dysfunction is the protein tau. An international team of researchers has reported a new mechanism by which boosting the natural metabolite NAD⁺ can protect the brain from the degeneration associated with AD. NAD⁺ (nicotinamide adenine dinucleotide, oxidized form) is a vital metabolite involved in energy metabolism and neuronal resilience in the body. It normally declines with...
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NATIONAL NUT DAY National Nut Day is observed annually on October 22nd. This day is NOT about the neighbor that lives down the street or the co-worker who sings with their headphones on. It is a food holiday celebrating a healthy and nutritious snack. #NationalNutDay Nuts are a highly prized food and energy source and are a primary source of nutrients for both humans and wildlife. Many of them are used in cooking, eaten raw, sprouted, or roasted as a snack food, and pressed for oil that is used in cookery and cosmetics. The fats found in nuts, for the...
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Run time 19 m 26 s Minnesota Senator Fought the Release of This Bodycam.
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Alzheimer’s disease, long seen as a disorder of the aging brain, may actually begin in an unexpected place: the mouth.Researchers reported evidence that a bacterium commonly associated with chronic gum disease could play a direct role in the development of Alzheimer’s. The study, published in Science Advances, details how Porphyromonas gingivalis, the pathogen behind periodontitis, was detected in the brains of Alzheimer’s patients. The findings come from an international team of scientists that included Jan Potempa, a microbiologist at the University of Louisville. Potempa said the research offers some of the strongest evidence yet linking gum infection to Alzheimer’s pathology,...
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Can these toxic chemicals speed up or even cause the disease?As we age, we tend to become more focused on our health. Besides heart disease, diabetes, and cancer, we also have to worry about cognitive decline. Nearly seven million Americans live with Alzheimer’s disease, according to the Alzheimer’s Association. One in 14 people develops the disease by age 65, and one in three is diagnosed by 85. Among the most common neurodegenerative disorders, Alzheimer’s is also a top cause of death for individuals 65 and older. Now, new studies suggest that just three weeks of exposure to microplastics can lead...
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Scientists at UCSF have uncovered a surprising culprit behind brain aging: a protein called FTL1. In mice, too much FTL1 caused memory loss, weaker brain connections, and sluggish cells. But when researchers blocked it, the animals regained youthful brain function and sharp memory. The discovery suggests that one protein could be the master switch for aging in the brain — and targeting it may one day allow us to actually reverse cognitive decline, not just slow it down.
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St.Jude researchers revealed that midkine blocks amyloid beta from forming harmful clumps linked to Alzheimer’s. Without it, the damaging assemblies accelerate, but with it, growth halts. The finding could inspire new drugs that harness midkine’s protective power.
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Gates is calling on global innovators to harness A.I. against the growing Alzheimer’s crisis.More than 7 million Americans are currently living with Alzheimer’s disease—a figure expected to rise as life expectancies increase. To help accelerate progress, Bill Gates and a coalition of partners are backing a new A.I. competition designed to spur breakthroughs in Alzheimer’s and related dementia research. Unveiled today (Aug. 19) by the Alzheimer’s Disease Data Initiative (AD Data Initiative), the competition will award a $1 million prize to a team that successfully utilizes agentic A.I. to develop innovative solutions. The resulting tools will be made publicly available...
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What is the earliest spark that ignites the memory-robbing march of Alzheimer's disease? Researchers may have found an answer: lithium deficiency in the brain. The work shows that lithium occurs naturally in the brain, shields it from neurodegeneration, and maintains the normal function of all major brain cell types. The findings are based on experiments in mice and on analyses of human brain tissue and blood samples from individuals in various stages of cognitive health. The scientists found lithium loss in the human brain is one of the earliest changes leading to Alzheimer's, while in mice, similar lithium depletion accelerated...
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