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Biden's Little Helper The Gaffing Stoned What a drag it is getting old "He is different today," I hear every voter say Biden needs something today to keep him up And though he's not really ill, there's a little yellow pill He goes running for the shelter of his brain’s little helper And it helps him on the campaign trail, he can talk through the day Doctor, please, some more of these Outside the door, he took four more What a drag it is getting old "Voters aren't the same today," I hear Jill Biden say They just don't appreciate...

Getting more than six hours of quality sleep a night may help prevent, or slow the progression of Alzheimer's disease, according to new research. The research has found the accumulation of beta-amyloid plaques in the brain, a process linked to the development and progression of the disease, is closely related to individual sleep patterns. The study highlighted that poorer sleep quality, and lower quantity, were associated with faster accumulation of beta-amyloid in the brain, in older adults whose memory and thinking were still unimpaired. Associate Professor Stephanie Rainey-Smith said the findings suggest new hope for us all. "Alzheimer's disease is...

Researchers have found a potential link between putative retinal gliosis and Alzheimer's disease. The study demonstrates that putative retinal gliosis could be a sign of Alzheimer's disease-related neuroinflammation, an inflammatory response within the brain or spinal cord. Putative retinal gliosis refers to changes in the retina caused by activation of glial cells, which are support cells that become activated when there is damage or disease in the retina. In this study, Edmund Arthur, O.D., Ph.D. found that presumed neuroinflammation was larger in the retina of preclinical Alzheimer's disease patients compared to similarly aged controls, like from postmortem tissues and animal...

By virtually all accounts, Joe Biden's debate performance was disaster. At first the left was in denial and eventually shifted to "it was a just a bad night." The family gathered together at Camp David for a summit to determine Biden's future course. It was speculated that the family might be trying to talk Biden into stepping down, but apparently that was inaccurate. It was reported that they were rather displeased at some advisers. Members of Joe Biden’s family privately trashed his top campaign advisers at Camp David this weekend, blaming them for the president’s flop in Thursday’s debate and...

I've heard that sundowning may happen with dementia. What is sundowning and how is it treated? Answer From Jonathan Graff-Radford, M.D. The term "sundowning" refers to a state of confusion that occurs in the late afternoon and lasts into the night. Sundowning can cause various behaviors, such as confusion, anxiety, aggression or ignoring directions. Sundowning also can lead to pacing or wandering. Sundowning isn't a disease. It's a group of symptoms that occurs at a specific time of the day. These symptoms may affect people with Alzheimer's disease and other types of dementia. The exact cause of sundowning is not...

The campaign previously said the single best hour of fundraising came immediately after Biden's debate against Trump The re-election campaign for President Biden says it has raised a whopping $27 million since his rocky debate performance against former President Trump. From the day of the debate through Friday evening, the Biden-Harris campaign told Fox News that it had raised $27 million. The updated figure comes after the campaign said on Friday that it raised $14 million in "a sign of strength of our grassroots support" on debate day and the morning after. The campaign also noted Friday that 11 p.m....

Neurodegenerative diseases (NDDs) result in irreversible damage to the brain and nervous system. Research into these diseases typically focuses on the brain, but mouse studies from the last few years suggest that the microbiome plays a role in the onset and progression of some NDDs, as well. Those researchers report a new link in humans between a metabolite produced by gut microbes and three NDDs. Their analysis suggests that the metabolite DHPS (2,3-dihydroxypropane-1-sulfonate) may help answer critical questions about how sulfur metabolism pathways can connect the microbiome to these diseases. DHPS has not previously been detected in people, and the...

Horses were domesticated at least twice, researchers report June 6 in Nature. Genetic data suggest Botai hunter-gatherers in Central Asia may have been the first to domesticate the animals for milk and meat around 5,000 years ago. That attempt didn't stick. But other people living north of the Caucasian Mountains domesticated horses for transportation about 4,200 years ago, the researchers found.Those latter horses took the equine world by storm. In just a few centuries, they replaced their wild cousins and became the modern domestic horse...ancient people from southwest Asia known as the Yamnaya have been credited with being the first...

It may or may not be the most significant retraction of a scientific paper ever, but it certainly is in the ballpark. The paper helped create and sustain the theory that amyloid protein buildups caused the symptoms of Alzheimer's Disease and was one of a number of apparently fraudulent papers written by Sylvain Lesné, a professor at the University of Minnesota, Twin Cities. All the paper's authors agreed to retract, save Lesné, who has been under investigation for manipulating data. "Authors of a landmark Alzheimer’s disease research paper published in Nature in 2006 have agreed to retract the study in...

A substance naturally occurring in pomegranates, strawberries and walnuts can improve memory and treatment of Alzheimer's disease, a new study concludes. Forgetfulness, difficulty finding words and confusion about time and place. These are some of the most common symptoms of Alzheimer's disease. Now researchers have discovered that an ordinary fruit can help. "Our study on mouse models with AD shows that urolithin A can alleviate memory problems and other consequences of dementia," says Vilhelm Bohr. "Even though the study was conducted on mouse models, the prospects are positive. So far, research has shown promising results for the substance in the...

Donald Trump has reacted to a viral video of President Joe Biden freezing in a half-bent position during a ceremony on Thursday marking the 80th anniversary of D-Day in Normandy, France. In the video, Biden is seen on stage with French president Emanuel Macron, who remains standing as Biden awkwardly bends down, as if to sit. Biden then holds the squat position, before bobbing up and down slightly, apparently unable to decide if he will sit or stand. As a voice on the loud speaker announces that US Defense Secretary Lloyd Austin is about to speak, First Lady Jill Biden...

It has long been known that a hallmark of Alzheimer's disease, and most other neurodegenerative diseases, is the clumping together of insoluble protein aggregates in the brain. During normal disease-free aging, there is also an accumulation of insoluble proteins. Researchers have recently completed a systematic study in worms that paints an intricate picture of the connections between insoluble proteins in neurodegenerative diseases and aging. Furthermore, the work demonstrated an intervention that could reverse the toxic effects of the aggregates by boosting mitochondrial health. "Our study shows how maintaining healthy mitochondria can combat protein clumping linked to both aging and Alzheimer's,"...

"Keeps Falling" - The Ballad of Joe Biden

President Biden was mocked by critics Wednesday over the number of jump cuts in his 14-second debate challenge to Donald Trump — with one wag on Twitter likening the brief video to “a Claymation film.” The video of Biden, 81, was released at 8 a.m. and featured the incumbent taunting the former president to “make my day” by agreeing to a on-one-on debate. “In a super short 14 second video, the Biden campaign needed to do 5 jump cuts because Crooked Joe couldn’t deliver a clean reading. Total disaster,” Trump campaign official Steven Cheung posted on X. “Biden’s video has...

Protein imbalances that increase brain cell excitability may explain why individuals with Alzheimer's disease (AD) who also experience seizures demonstrate more rapid cognitive decline than those who do not experience seizures. These imbalances may be present in the brains of individuals before the onset of AD symptoms. The team found that an existing drug called rapamycin, initially developed as an immunosuppressant for organ transplant patients that suppresses signaling between neurons, was able to regulate the over-excited neurons in mouse models of AD and seizures, and preserve cognitive function, like memory and the ability to learn new things. "Experts used to...

President Biden raised eyebrows Wednesday morning, when he appeared disoriented while welcoming Japanese Prime Minister Fumio Kishida to the White House for a state visit. Biden, 81, and Kishida, 66, greeted one another before shaking the hands of members of both the US and Japanese delegations on the South Lawn. The leaders then mounted a stage for the national anthems of both countries, before reviewing US military honor guards. Ahead of the review, Biden and Kishida were greeted with a salute by a military aide.

On Friday, Joe Biden visited the site of the collapsed Francis Scott Key Bridge in Maryland — the same bridge he claimed he commuted over regularly via rail, even though it has no tracks — and he just couldn't help himself by invoking the death of his son Beau in order to play the empathy card. "Well, to all the families and loved ones who are grieving: I’ve come here to grieve with you. We all are," he said. "It’s not the same, but I know a little bit about what it’s like to lose a piece of your soul...

New research conducted in mice offers insights into what's going on at the molecular level that could cause people with diabetes to develop Alzheimer's disease. The study adds to a growing body of research on the links between type 2 diabetes and Alzheimer's disease, which some scientists have called "type 3 diabetes." The findings suggest that it should be possible to reduce the risk of Alzheimer's by keeping diabetes well controlled or avoiding it in the first place, according to researchers. Narendra Kumar led the study. "We think that diabetes and Alzheimer's disease are strongly linked," Kumar said, "and by...

Fiber is essential for the digestive system. It helps maintain a healthy weight and lowers the risk of diabetes, heart disease and certain cancers. Getting the right amount of fiber, whether through food or drinks, is a great way to relieve constipation. In addition to all that, fiber supplements could improve brain function in older adults, according to a new study. The study followed individuals over the age of 60 for a 12-week period. Results found those who took prebiotic fiber supplements showed a "significant improvement in memory." The study evaluated the gut microbiome and its correlation with both cognitive...

A new study shows that a ketogenic diet significantly delays the early stages of Alzheimer's-related memory loss in mice. This early memory loss is comparable to mild cognitive impairment in humans that precedes full-blown Alzheimer's disease. The ketogenic diet is a low-carbohydrate, high-fat, and moderate-protein diet, which shifts the body's metabolism from using glucose as the main fuel source to burning fat and producing ketones for energy. Researchers previously found that mice lived 13% longer on ketogenic diets. The new study, which follows up on that research, found that the molecule beta-hydroxybutyrate, or BHB, plays a pivotal role in preventing...