Free Republic
Browse · Search
General/Chat
Topics · Post Article

Skip to comments.

Scientists discover 'master switch' in the human body that reverses cell ageing
Daily Mail ^ | 02/25/2025 | William Hunter

Posted on 02/25/2025 9:18:12 PM PST by SeekAndFind

A cure for ageing sounds like something right out of a wild science-fiction film like The Substance.

But scientists could now be close to making this a reality.

Researchers from Osaka University, Japan claim to have found a cellular 'master switch' which can reverse the process of ageing.

This protein, called AP2A1, could be the key to future treatments that will turn back the body's biological clock and undo the damage caused by old age.

As our bodies get older, we build up a growing number of old or 'senescent' cells which stop dividing and functioning as they should.

These 'zombie cells' don't die but rather continue to grow and pump out inflammatory chemicals which contribute to age-related diseases.

However, the researchers found that they could turn senescent cells back into young, healthy cells simply by reducing the amount of the protein AP2A1.

In theory, that means scientists could remove the cause of age-related diseases like Alzheimer's or arthritis by reversing the process of senescence at the cellular level.

The body's ageing process is incredibly complex and there is no single factor responsible for why we get old.

However, cell senescence is one process which appears to play a significant role in bringing on the negative consequences of getting older.

Professor Richard Faragher, an expert on cell ageing from the University of Brighton who was not involved in the study, says: 'Normal cells monitor the number of times they have been called on to divide as a cancer prevention mechanism.

'So, after a variable number of divisions, these cells become senescent which means they activate pathways to ensure they will not divide again.'

Senescent cells also 'radically change the way in which they behave' and start to produce inflammatory molecules and enzymes which degrade the surrounding tissue.

(Excerpt) Read more at dailymail.co.uk ...


TOPICS: Health/Medicine; Science; Society
KEYWORDS: ageing; aging; alzheimers; ap2a1; arthritis; cells; fakenews
Navigation: use the links below to view more comments.
first 1-2021-4041-46 next last

1 posted on 02/25/2025 9:18:12 PM PST by SeekAndFind
[ Post Reply | Private Reply | View Replies]

To: SeekAndFind

finally. How do I turn on my switch?


2 posted on 02/25/2025 9:35:41 PM PST by Strict9
[ Post Reply | Private Reply | To 1 | View Replies]

To: Strict9

Mas tequila


3 posted on 02/25/2025 9:44:20 PM PST by doorgunner69 (Your oath of enlistment has no expiration date)
[ Post Reply | Private Reply | To 2 | View Replies]

To: SeekAndFind

Playing with that switch, I hear will make ya go blind.


4 posted on 02/25/2025 9:52:54 PM PST by know.your.why
[ Post Reply | Private Reply | To 1 | View Replies]

To: SeekAndFind

Great news. Some exciting advances happening in medicine lately. Saw a segment on gretas show shere a doc was discussing kidnet cancer and a new victim specific designer medicine can be createc now which seeks,out, t a rgets and cetros the cancer cells only- the method has been around ashile, but tneyve i prkved it tremendously in the last fes years, and in a small study of 9 patients, all nine are cancer free now after surgery and the meds which mopped up the remaining cells.

Few years zway of course, but they are very encouraged by it.


5 posted on 02/25/2025 9:56:19 PM PST by Bob434 (...Time flies like an arrow, fruit flies like a banana)
[ Post Reply | Private Reply | To 1 | View Replies]

To: SeekAndFind

Speaking of aging is it not incredible how George Soros looks like the evil emperor in Star Wars?

In all seriousness the evil Emperor was just a character in a movie. George Soros is an evil man in reality. Megalomania if in power always does much evil. Carl Marx and Engels were not megalomaniacs but were the fathers of Marxism. Their ideals were twisted into tyranny as their ideals were totally impossible in human society and will never be nor work. Their philosophy though noble always result in tyranny, death and war. Just as Cambodia. If you do not what happened in Cambodia you have malignant stupidly.


6 posted on 02/25/2025 9:57:06 PM PST by cpdiii (cane cutter, deckhand, oilfield roughneck, drilling fluid tech, geologist, pilot, pharmacist ,MAGA)
[ Post Reply | Private Reply | To 1 | View Replies]

To: Strict9

LOL

You gotta reach real deep...and a little to the right...but use a flashlight cause it’s hard to find... :)


7 posted on 02/25/2025 9:57:21 PM PST by dp0622 (Tried a coup, a fake tax story, tramp slander, Russia nonsense, impeachment and a virus. They lost.)
[ Post Reply | Private Reply | To 2 | View Replies]

To: know.your.why

But it’s okay up until you only need glasses.


8 posted on 02/25/2025 9:58:14 PM PST by citizen (Political incrementalism is like compound interest for liberals - every little bit adds up.)
[ Post Reply | Private Reply | To 4 | View Replies]

To: SeekAndFind

For how long will the effects of aging be reversed?
How many times can this be done on the body with the same level of effect, or does s tolerance develop over repeated uses of this method?


9 posted on 02/25/2025 10:00:30 PM PST by lee martell
[ Post Reply | Private Reply | To 1 | View Replies]

To: SeekAndFind

I don’t know that this is a good thing. Picture an immortal George Soros.


10 posted on 02/25/2025 10:02:43 PM PST by Lazamataz (The BEST birthday present I ever got WAS DONALD TRUMP WINNING IN 2024!!!)
[ Post Reply | Private Reply | To 1 | View Replies]

To: nutmeg

bkmk


11 posted on 02/25/2025 10:05:13 PM PST by nutmeg (Proud irredeemable deplorable bitter clingin’ piece of garbage)
[ Post Reply | Private Reply | To 1 | View Replies]

To: Bob434

AI is going to speed the advances tremendously. Maybe even going from cells directly to humans in a few years before mice get their senescent proteins removed.


12 posted on 02/25/2025 10:07:46 PM PST by erlayman (E )
[ Post Reply | Private Reply | To 5 | View Replies]

To: SeekAndFind

I feel like I read about the new key to forever youth every 5 years.


13 posted on 02/25/2025 10:08:08 PM PST by CaptainK ("No matter how cynical you get, it is impossible to keep up” )
[ Post Reply | Private Reply | To 1 | View Replies]

To: SeekAndFind

14 posted on 02/25/2025 10:09:25 PM PST by Angelino97
[ Post Reply | Private Reply | To 1 | View Replies]

To: Strict9

Turn on, tune in....wasn’t that a Timothy Leary slogan? Not really suggesting illegal drugs.... Maybe go dancing instead.


15 posted on 02/25/2025 10:10:42 PM PST by Veto! (Tump Is Superman)
[ Post Reply | Private Reply | To 2 | View Replies]

To: SeekAndFind

No thanks. I’ve already lived longer than anyone in my immediate family. My only goal is to not outlive my two sons.


16 posted on 02/25/2025 10:20:31 PM PST by mass55th (“Courage is being scared to death, but saddling up anyway.” ― John Wayne)
[ Post Reply | Private Reply | To 1 | View Replies]

To: erlayman

Yep ai will help remendously, especially where meds need to be fine tuned to specific cancers which need special developments based on a person’s unique DNA. The bad thin about ai thouhg was when the investors that pres Trump introduced , the multi billionairs he brought up on stage with him, they giddily said that they were excited about how hey are gonna be able to create new mRNA’s in just days and xpeed them to market, for, you know, “for the good of mankind” ax they said- the one fella especially a ent on about it, and it was truly creepy how he described it.

Ai is gonna be a great thing, but also a dangerous thing in the wrongmhands, and frankly those 3 folks up on stage described some really disturbing things about heir plans for use of the ai and the coming “super ai” that the Japanese fella spoke about.


17 posted on 02/25/2025 10:28:21 PM PST by Bob434 (...Time flies like an arrow, fruit flies like a banana)
[ Post Reply | Private Reply | To 12 | View Replies]

To: SeekAndFind

Hey coach! Put me in!

I’ll get to re-celebrate 92 birthdays...


18 posted on 02/25/2025 10:32:56 PM PST by SuperLuminal (Where is rabble-rising Sam Adams now that we need him? Is his name Trump, now?)
[ Post Reply | Private Reply | To 1 | View Replies]

To: Bob434

Ai is gonna be a great thing, but also a dangerous thing in the wrongmhands, and frankly those 3 folks up on stage described some really disturbing things about heir plans for use of the ai and the coming “super ai” that the Japanese fella spoke about
_____________

“And in those days shall men seek death, and shall not find it; and shall desire to die, and death shall flee from them.”

~Revelation 9:6


19 posted on 02/25/2025 10:49:22 PM PST by Fai Mao (Democrats need to go to prison.)
[ Post Reply | Private Reply | To 17 | View Replies]

To: SeekAndFind
Island City Opening Credits (1994 Unsold Pilot)
20 posted on 02/25/2025 11:01:09 PM PST by \/\/ayne (I regret that I have but one subscription cancellation notice to give to my local newspaper)
[ Post Reply | Private Reply | To 1 | View Replies]


Navigation: use the links below to view more comments.
first 1-2021-4041-46 next last

Disclaimer: Opinions posted on Free Republic are those of the individual posters and do not necessarily represent the opinion of Free Republic or its management. All materials posted herein are protected by copyright law and the exemption for fair use of copyrighted works.

Free Republic
Browse · Search
General/Chat
Topics · Post Article

FreeRepublic, LLC, PO BOX 9771, FRESNO, CA 93794
FreeRepublic.com is powered by software copyright 2000-2008 John Robinson