These mice are the same age but the lower has not been given anti-ageing drugs - Sarah Knapton
Posted on 04/03/2019 11:35:30 AM PDT by Red Badger
With its pudgy body, tired eyes and hair loss, the lower mouse could easily be the father of the sprightly and alert animal nestling alongside.
But they are actually the same age, the result of extraordinary trials of drugs which are slowing down or even reversing the ageing process.
Scientists now believe that ageing itself is responsible for many major conditions such as Alzheimer’s, Parkinson’s, arthritis, cancer, heart disease, and diabetes. And they think they have found a way to turn it off.
Anti-ageing drugs - dubbed ‘senolytics’ - are currently being trialled in humans and unlike previous tests which have focussed on a single disease, these drugs work like a broad-spectrum antibiotic, preventing or alleviating most age-related illnesses and frailty.
Scientists at The Mayo Clinic, who first coined the term senolytics, already have six trials in humans under way and plan to start six more shortly. If successful, they estimate that drugs to slow down ageing could be ready within two years.
In mice, the drugs extend lifespan by 36 per cent, the equivalent of adding around 30 years to humans, and crucially the animals remained in good health.
Clinical geriatrician Dr James Kirkland, Director of the Robert and Arlene Kogod Center on Aging at Mayo Clinic, said: “Most people don’t want to live to 130 and feel like they’re 130 but they wouldn’t mind living to 90 or 100 and feel like they’re 60. And now that can actually be achieved in animals.
“Ageing itself is the highest risk factor for most of the chronic diseases. And if you get one age-related disease, you’ve got a huge chance of having several.
“You tend to find older individuals who are completely healthy and are playing 18 rounds of golf a day, or they’ve got three,five or 10 different conditions.
(Excerpt) Read more at uk.news.yahoo.com ...
These mice are the same age but the lower has not been given anti-ageing drugs - Sarah Knapton
Young women, scotch and cigarettes seem to work
Ran into a friend I hadn’t seen in years.
He looked mid 79’s
Weird, since we are both 55...
Keith Richards?.........................
Swell, so the Soros and Hillarys of the world lived into their 100s.
Cute.
The upper one looks as if he's had his face lifted at least a few times.
Best way to prolong your life is not to die.
That would be impressive.
Some children alive today may live to be hundreds of years old.
Drugs to stop aging have been just around the corner since at least the 1970s. I remember reading an article in Science Digest in the mid 1970s that confidently predicted that a treatment to stop aging was only 5 to 10 years away. Of course, at the same time they were also predicting Global Cooling and the coming of the next ice age.
Meanwhile, scientists have cured cancer in mice dozens of times over the years. The treatments just don’t translate to humans.
I look the same today as I looked 20 years ago. For some reason, no one else seems to think so.
So where are the experts here that can tell us where we can get senolytics.
It looks like curcumin and Quercetin might work.
I bought some powdered Quercetin from Amazon but because it is in powdered form I havent been using it. it discolors everything
I’m gonna die of old age waiting for drugs that reverse old age
I ran into Keith Richard’s at a party 15 years ago and wondered how he was still alive.
A week after I walked pass Mick Jagger and thought he looked pretty good, considering and was a bit jealous of his attire, which was beaitiful
Uh huh. May not want to (afford to) live to be 130 but might be nice to be 90 and feel like you are 60.
Sounds like a precarious scenario to me. What happens when you are 90 and want to continue to live but can’t afford to or become a burden to others or get to be 100 or 120 and start feeling and having the problems of a “normal” 80 or 90 year old. What then?
And everybody else my age is getting old!
Sounds like a scam.
But, NIA apparently funded the mouse studies.
“Some children alive today may live to be hundreds of years old.”
Lol.
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