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Can Viagra prevent or reverse Alzheimer’s disease? Older men’s ship may be coming in. New research from the Cleveland Clinic suggests the erectile-dysfunction drug could ward off cognitive decline, illustrating how artificial intelligence can help scientists repurpose old medications for new diseases. The study, published this month in the Journal of Alzheimer’s Disease, builds on earlier research by the Cleveland Clinic that identified sildenafil, the generic name for Viagra, as a promising Alzheimer’s treatment. Researchers first identified genes associated with the disease’s pathology, amyloid plaque and tau tangles in the brain. They then mapped out the molecular interplay among more...

Daily Mail US @DailyMail Biden, 81, says the key to his marriage is 'good sex' https://trib.al/VR7xmIS 9:58 AM · Feb 23, 2024

A trio of medical researchers has found that many men experiencing erectile dysfunction can overcome much of the problem by simply engaging in aerobic exercise. Prior research has shown that many older men experience problems with achieving an erection when they want to have sex. In this new study, the researchers identified that some research has shown that erectile dysfunction is quite often associated with cardiovascular health and associated symptoms such as inflammation and narrowing and/or hardening of the arteries. They also noted that regular aerobic exercise has been shown to reduce symptoms of cardiovascular disease. This made them wonder...

Pfizer’s erectile dysfunction medication Viagra can reduce the risk of developing Alzheimer’s disease by up to 69%. Credit: Audrey Disse, CC BY-SA 3.0 Research published recently suggests that Pfizer’s erectile dysfunction drug Viagra can decrease the risk of developing Alzheimer’s disease by up to 69 percent. The research, which was published in Nature, found that the medication has a direct effect on brain health and significantly reduces the toxic proteins that can cause dementia. The study’s findings are so promising that the drug may someday be used to counter dementia. A new team of experts is preparing to conduct another...

The U.S. Food and Drug Administration has approved over-the-counter marketing for Eroxon, as a first-of-its-kind topical gel for erectile dysfunction. Men with erectile dysfunction will now have the option of using a topical gel to treat the condition. The U.S. Food and Drug Administration has approved over-the-counter marketing for the product, called Eroxon, as a first-of-its-kind medical product. The British pharmaceutical firm Futura Medical makes the gel. "FDA set a very high standard in evaluating the effectiveness and safety of De Novo Medical Devices. I am delighted that we met this standard," Futura CEO James Barder said in a news...

As our chart illustrates, the loss of exclusivity in major markets such as Europe, Japan and most importantly the United States had a significant effect on Viagra sales, which declined by almost 70 percent between 2012 and 2018. 25 years after its initial approval, Viagra is no longer part of Pfizer either. In 2020, the company’s off-patent branded and generics business Upjohn, which included Viagra, was spun-off and combined with Mylan to create a new company called Viatris.

The company took the decision after the business was being influenced by economic sanctions imposed on Russia after the invasion of Ukraine. The US pharmaceutical company Viatris has informed the Russian Ministry of Industry and Trade that the supply of the drug Viagra, in tablet format, has been suspended in the Russian market. "Viatris LLC has informed us about the suspension of the supply of the drug Viagra in the pharmaceutical form of a pill", said the ministry, quoted by the Russian news agency TASS. According to the American pharmaceutical company, the decision was taken after the business was influenced...

A comprehensive research study manuscript examining the impact of erectile dysfunction drugs on major adverse cardiovascular events (MACE) and mortality has been published. This study marks a significant medical milestone, as it's the first time the association between the use of PDE-5i drugs and cardiovascular health has been explored in a large population of relatively low-risk men with ED in the United States. In this study, scientists analyzed health records of more than 70,000 men with ED. According to the findings of this large-population study, men who took Viagra, Cialis, Levitra and other drugs of the same class for erectile...

A UN official claimed Russia is using rape as its “military strategy” in Ukraine — providing soldiers with drugs to sexually assault civilians. “When you hear women testify about Russian soldiers equipped with Viagra, it’s clearly a military strategy,” Pramila Patten, UN special representative on sexual violence in conflict, told the AFP. Patten added that the UN has verified “more than a hundred cases” of rape or sexual assault since the invasion began in February. Victims have largely included girls and women, but boys and men have been raped, too. In September, the head of the organization’s Independent International Commission...

President Joe Biden is planning to extend his vacation this week after he wraps up his time on Kiawah Island in South Carolina. According to Federal Aviation Administration (FAA) data cited by the Associated Press, Biden plans to be in Wilmington, Delaware, from Tuesday until Friday after he leaves Kiawah Island.

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Alzheimer’s disease (AD) is the most common form of dementia. It is expected to affect 16 million Americans by 2050. The hallmarks of AD are amyloid plaques and tau neurofibrillary tangles in the brain. Efforts to develop new drugs that directly target amyloid or tau proteins haven’t yielded significant clinical benefits for patients. Another approach to developing AD treatments would be to seek existing drugs that could potentially be repurposed. A team of researchers led by Dr. Feixiong Cheng at the Cleveland Clinic developed a computational method for identifying FDA-approved drugs that might be effective against AD. NIH’s National Institute...

Viagra is a miracle drug that keeps on growing. A 37-year-old nurse in England is back on her feet, thanks to the little blue pill. The fully vaxxed Monica Almeida tested positive for the Chinese Wu-flu on October 31. Soon she had the Chinese sneeze and pneumonia as well. She also has asthma and is a bit on the portly side. By November 16 she was in a medically induced coma. That’s when she caught an infection. She also had to undergo a tracheotomy just over two weeks later. She was in bad shape. Her parents were contacted and told...

A nurse who spent 28 days in a Covid coma fighting for her life has been saved after medics gave her Viagra. Mother-of-two Monica Almeida, 37, from Gainsborough, Lincolnshire, was just three days away from having her ventilator turned off. Mrs Almeida was given the erectile dysfunction drug by her colleagues at Lincoln County Hospital. The ‘miracle’ drug caused her condition to improve in just a week and the level of oxygen she needed to drop by half as it opened up her airwaves. 'I had a little joke with the consultant after I came round because I knew him....

The Cleveland Clinic released a statement today announcing some unexpected but exciting news: Viagra may be an effective preventative for Alzheimer’s Disease (AD).A new Cleveland Clinic-led study has identified sildenafil – an FDA-approved therapy for erectile dysfunction (Viagra) and pulmonary hypertension (Ravatio) – as a promising drug candidate to help prevent and treat Alzheimer’s disease The research team, led by Feixiong Cheng, Ph.D., of Cleveland Clinic’s Genomic Medicine Institute, made the discovery as part of a data-mining study. They performed a large-scale computational analysis of medical insurance data from over 7 million patients, evaluating medicines already FDA-approved and in use...

Usage of the medication sildenafil – better known to most as the brand-name drug Viagra – is associated with dramatically reduced incidence of Alzheimer's disease, new research suggests. According to a study led by researchers at the Cleveland Clinic, taking sildenafil is tied to a nearly 70 percent lower risk of developing Alzheimer's compared to non-users. That's based on an analysis of health insurance claim data from over 7.2 million people, in which records showed that claimants who took the medication were much less likely to develop Alzheimer's over the next six years of follow up, compared to matched control...

Viagra, used to treat sexual impotence, can strongly suppress abnormal heart rhythms known as arrythmias in sheep according to scientists. In female sheep, the drug—also known as sildenafil—was able to suppress an arrythmia called Torsades de Pointes within 90 seconds by reducing the frequency of irregular heart rhythms caused by abnormal handling of calcium. It also reduced the probability of Torsades de Pointes, which can lead to sudden cardiac death. However, the team believe the drug could treat other arrythmias as well. Cardiac arrythmias often follow a heart attack, or result from heart disease. Though often benign , they can...

Spike Lee’s next project will be a movie musical about the origin story of Viagra, Pfizer’s erectile dysfunction drug. The Entertainment One film is based on David Kushner’s Esquire article titled “All Rise: The Untold Story of the Guys Who Launched Viagra.” Lee is directing the untitled musical from a screenplay he wrote with Kwame Kwei-Armah. The movie will feature original songs and music penned by Stew Stewart and Heidi Rodewald, the duo behind the Tony-winning musical “Passing Strange.” In a statement, Lee said, “First And Foremost,I Thank Ms. Jacquelyn Shelton Lee. I Thank My Late Mother For As She...

Nitric oxide is emerging as a potential treatment for COVID-19, and doctors around the world are testing it again after it had shown to kill another coronavirus, SARS. "It's a pretty remarkable drug," Massachusetts General Hospital critical-care specialist Dr. Lorenzo Berra, who is leading a trial, told the L.A. Times. "It has a risk profile that is minimal." . . . . Dr. Berra said nitric oxide was also found to kill a coronavirus that leapt from bats to humans, University of Leuven in Belgium researchers found in 2004, according to the report. "The story ended there," Berra told the...

Retiring Alderman Danny Solis (25th Ward) received sex acts, Viagra, free weekend use of an Indiana farm once owned by Oprah Winfrey and a steady stream of campaign contributions in exchange for shepherding official City Council actions, according to allegations in a federal court affidavit obtained by the Chicago Sun-Times. Although no charges have been filed publicly against Solis, the 2016 affidavit lays out in detail a federal corruption case against the veteran alderman, who was one of the closest City Council allies of Mayor Rahm Emanuel and Emanuel’s predecessor, Richard M. Daley. It also alleges that among the people...