Free Republic

WASHINGTON (AP) — President Joe Biden, struggling to convince Americans that he's improved their lives as he runs for reelection, hailed his administration's Tuesday announcement that several drugs would be targeted for Medicare's first-ever price negotiations. The drugs include the blood thinner Eliquis, diabetes treatment Jardiance and eight other medications. The negotiation process was authorized under the Inflation Reduction Act, which Biden signed last year, capping decades of debate over whether the federal government should be allowed to haggle with pharmaceutical companies. Any lower prices won't take effect for three years, and the path forward could be further complicated by...

A U.S. drug company did not openly share or perform further studies on a successful rheumatoid arthritis medicine that internal researchers suggested was reducing the risk of Alzheimer's disease by 64 percent, according to Washington Post article published Tuesday. Researchers at Pfizer reportedly urged the firm to conduct a clinical trial after finding the potential hidden benefit of the anti-inflammatory drug Enbrel while analyzing insurance claims. It was estimated to cost $80 million to conduct the trial, and Pfizer decided to pass. Pfizer told the Post it did not pursue the clinical trial because its success rate would likely be...

A drug injected into the spine has produced rapid improvements in verbal fluency in a trial of 12 patients with Alzheimer’s disease. Etanercept (Enbrel), an antiTNF drug developed to treat rheumatoid arthritis, transformed the behaviour of some patients in a matter of minutes, the researchers say. The results, published in BMC Neurology, are the latest in a series of bold claims made by Edward Tobinick, from a private medical group in Los Angeles, and Hyman Gross, of the University of Southern California. Their theory is that TNF is used in the brain to regulate the transmission of nerve impulses. They...

In a new report, U.S. researchers describe the improvement in brain function that occurred in a patient with Alzheimer's disease just minutes after receiving an injection in the spine of the arthritis drug Enbrel (also known as etanercept). For instance, just prior to treatment the patient was agitated and could not name the state. Ten minutes after treatment, he appeared calmer, more attentive, less frustrated and was able to correctly name the state. Further improvements in mental functioning, memory, and other cognitive parameters were noted at 2 hours. Dr. Edward L. Tobinick, from the University of California at Los Angeles,...

An arthritis drug shows promise in a small, experimental study targeting a root cause of Alzheimer's -- inflammation in the brain. WALTER Skotchdopole worked for 20 years as a police officer and 20 years in the film industry before succumbing to the relentless decline of Alzheimer's disease. In his prime, he joked with everyone he met. By his early 70s, he had become a shell of his former self. "He's there, but he's not," says his son James Skotchdopole. "There's no real interaction, no real stake in life." Walter Skotchdopole had tried several drugs, with no noticeable improvement. But when...

AP MEDICAL WRITER CHICAGO -- Rheumatoid arthritis patients taking Humira or Remicade face triple the risk of developing several kinds of cancer and double the risk of getting serious infections, a study led by the Mayo Clinic found. The analysis builds on previous reports about the risks associated with Abbott Laboratories' Humira and Centocor's Remicade. But the earlier research focused mostly on one kind of cancer - lymphoma - and infections such as tuberculosis and pneumonia. The new study found an apparent link to other cancers, too, including skin, gastrointestinal, breast and lung tumors. It also quantifies the risks and...

July 11, 2002 | Kathleen Turner was on television recently talking about her pain and suffering. "The damage that I have, the damage I'll always have could have been prevented," the actress told "Good Morning, America" host Diane Sawyer on Feb. 19. Sawyer was sympathetic. Turner, she knew from a previous interview, had been battling rheumatoid arthritis for over a year now. "You're still in pain?" Sawyer asked. "Well," Turner responded, "as they say: only when you walk." Turner then went on to mention a Web site, www.ra-access.com, where fellow sufferers could get help. Sawyer eagerly repeated the site's address...