Acute pancreatitis (AP), which affects people of all ages, is one of the leading causes of hospital admission due to gastrointestinal diseases. To date, many questions regarding the optimal treatment of acute pancreatitis remain unanswered. A team combined human genetic epidemiology and animal models to discover and confirm the role of vitamin B12 in the prevention and mitigation of acute pancreatitis. Fan explained that the team first conducted meta-analyses of genome-wide association studies (GWAS). They then employed a Mendelian randomization approach to investigate the relationships between various one-carbon metabolism nutrients and the risk of pancreatitis. The analysis revealed that higher...