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Keyword: antimalarial

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  • Grapefruit Warning: It Can Interact with Common Medications

    07/21/2025 7:10:18 AM PDT · by Red Badger · 37 replies
    Healthline ^ | March 15, 2023 | Medically reviewed by Dena Westphalen, PharmD — Written by Matthew Thorpe, MD, PhD
    Grapefruit and its close relatives can increase the blood levels of certain drugs and cause serious side effects. Affected drugs include some medications for blood pressure and heart rhythm, among others. Grapefruit is a delicious citrus fruit with many health benefits. However, it can interact with some common medications, altering their effects on your body. If you’re curious about the grapefruit warning on many medicines, this article will help you understand why it’s there and what your options are. Here’s a closer look at 31 common drugs that may have dangerous interactions with grapefruit, as well as some alternatives. Note:...
  • RNA modifications in mitochondria promote invasive spread of cancer (Doxycycline reduces metastasis)

    06/30/2022 7:10:46 AM PDT · by ConservativeMind · 22 replies
    Medical Xpress / German Cancer Research Center / Nature ^ | June 29, 2022 | Michaela Frye et al
    Mitochondria are the power plants of cells, and they contain their own genetic material and RNA molecules. Scientists have now discovered that certain modifications in mitochondrial RNA boost the invasive spread of cancer cells by supporting protein synthesis in mitochondria. They have established that a specific gene expression signature correlating with high levels of mitochondrial RNA modifications is associated with metastasis and poor prognosis in patients with head and neck cancer. When the researchers blocked the responsible RNA modifying enzyme in cancer cells, the number of metastases was reduced. Certain antibiotics that suppress protein synthesis in mitochondria were also able...