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In a phase 1 trial, the oral drug Amycretin helped individuals lose up to 13.1% of their body weight in three months by targeting key appetite-regulating hormones, presenting a potential breakthrough in tablet-form obesity treatments. ============================================================================= Amycretin, an oral weight loss drug, led to up to 13% body weight reduction in three months, showing potential for continued weight loss. While well-tolerated, further long-term studies are needed to evaluate its safety and efficacy. Individuals who received a once-a-day oral weight loss drug had lost up to 13% of their body weight over three months, according to a recent presentation at the...

A new weight-loss pill made by Novo Nordisk — the manufacturer of Ozempic and Wegovy — helps patients shed weight twice as fast as the blockbuster injections, the company recently announced. The pill, called Amycretin, works similarly to the popular weight loss injections mimicking a natural hormone, GLP-1, which slows down the passage of food through the stomach, making people feel full for longer. However, this drug also stimulates a hormone called amylin, which also reduces hunger and slows stomach emptying. The combination of therapies seems to make it more effective.