Free Republic

Insulin resistance detected by routine triglyceride-glucose (TyG) index can flag people with early Alzheimer's who are four times more likely to present rapid cognitive decline, according to research. Neurologists reviewed records of 315 non-diabetic patients with cognitive deficits, including 200 with biologically confirmed Alzheimer's disease. All subjects underwent an assessment of insulin resistance using the TyG index and a clinical follow-up of three years. When patients were divided according to the TyG index, those in the highest third of the Mild Cognitive Impairment AD subgroup deteriorated far more quickly than their lower-TyG peers, losing >2.5 points on the Mini Mental...

Algerian boxer Imane Khelif will not be competing as expected in an upcoming World Boxing women's competition until completing a mandatory sex test, the organization announced on Friday. "Imane Khelif may not participate in the female category at the Eindhoven Box Cup, 5-10 June 2025 and any World Boxing event until Imane Khelif undergoes genetic sex screening in accordance with World Boxing’s rules and testing procedures," a letter sent by World Boxing to the Algerian Boxing Federation read. The letter also stated that World Boxing decided to adopt mandatory sex tests this month. "These new eligibility rules were developed with...

A new at-home saliva test could help identify men with a high risk of prostate cancer more accurately than blood tests, leading to earlier diagnosis and more successful treatment. Prostate cancer is the second most common form of cancer among men, after skin cancer. Currently, there is no standard test to screen for prostate cancer. A doctor may draw blood for a prostate-specific antigen test (PSA) or perform a rectal exam, but both of these types of screenings require follow-ups before a diagnosis can be made. PSA blood tests measure the level of a specific molecule produced by the prostate....

Anxiously anticipated federal data on student achievement show that children continued to lose ground in the years after the pandemic, particularly in reading, a troubling finding that has fed competing political narratives about education in America. The sobering report released Wednesday from the National Assessment of Educational Progress, sometimes called the Nation’s Report Card, showed that the path to recovery remains far rockier than experts had hoped — especially for students who were already struggling the most. The data showed that reading scores, which had fallen dramatically from 2019 to 2022, fell again in 2024, with a record portion of...

New research has found that biomarker testing in individuals at risk of lung cancer led to a major reduction in deaths. This study, conducted with 12,000 smokers and ex-smokers, demonstrates how biomarkers—measurable indicators of biological changes—can identify individuals at high risk of lung cancer, leading to earlier detection and significantly improved outcomes. Professor Frank Sullivan led a large-scale trial involving 12,000 smokers and ex-smokers. The study found that testing high-risk individuals with biomarkers led to a 40% reduction in deaths from lung cancer and other causes over five years. Biomarkers are measurable indicators of biological processes, such as proteins or...

The test aims to speed the detection of lung cancer, which often isn’t found until the later stages.UK scientists have developed a new test to speed up the detection of lung cancer – by finding “zombie cells” in people’s urine. Lung cancer, the deadliest type of cancer worldwide, killed nearly 227,000 people in the European Union in 2021. It often isn’t diagnosed until later stages when symptoms appear or it has spread to other parts of the body, making it more difficult to treat. The new tool, which uses an injectable sensor to test urine samples, aims to help...

Researchers have developed a nanoscale sensor to detect lung cancer by analyzing isoprene levels in breath, achieving high sensitivity and accuracy. The sensor, based on platinum-enhanced indium oxide nanoflakes, was integrated into a portable device that effectively distinguished lung cancer patients from healthy individuals in small tests. Detecting early-stage lung cancer may become easier thanks to an innovative approach that analyzes exhaled breath. Researchers developed an ultrasensitive nanoscale sensor capable of detecting isoprene levels in breath, a biomarker for lung cancer. By incorporating platinum-based nanoclusters, the Pt@InNiOx sensor achieved high sensitivity, with a detection threshold of just 2 parts per...

On October 5, a 4.5 magnitude earthquake struck near Semnan, Iran, raising online suspicions of a nuclear test amid escalating tensions with Israel. While some claim this could be related to Iran’s nuclear program, there is no concrete evidence to support the theory. Iran’s nuclear ambitions date back to the 1950s, with its current capacity to build a bomb under scrutiny.

A team of health and nutrition specialists has found that people on a ketogenic diet may experience an increase in LDL cholesterol levels, higher apolipoprotein B levels and reductions in certain gut bacteria. In their study, volunteers went on a ketogenic diet for a month so the researchers could study its impact on their bodies. A ketogenic diet consists of a drastic reduction in consumption of carbohydrates, replacing them with fats. In this new effort, the research team suspected that the diet may also lead to increases in LDL cholesterol levels and possibly other problems. To find out if that...

The traditional lipid panel may not give the full picture of cholesterol-related heart disease risk for many Americans, according to a study. There are different types of cholesterol particles that can cause heart disease, including low-density lipoproteins (LDL), very low-density lipoproteins (VLDL), and intermediate-density lipoproteins (IDL). LDL-C is a measure of the weight of cholesterol in LDL particles and is one of the most common tests people use to measure cholesterol risk. Every LDL, VLDL, and IDL particle has a single protein on its surface called apolipoprotein B (apoB). Prior research has shown that the number of "bad" cholesterol particles,...

The results of routine blood tests could be used to speed up cancer diagnosis among people with stomach pain or bloating, suggests a study. The study looked at data from more than 400,000 people aged 30 or older in the UK who had visited a GP due to stomach pain and more than 50,000 who had visited their GP due to bloating. Two thirds of this group had blood tests following their appointment. In the new study, the researchers found that people aged 60 or over who had gone to the GP with either stomach pain or bloating had a...

Monday, during an appearance on FNC’s “Hannity,” Sen. Lindsey Graham (R-SC) praised former President Donald Trump as the Republican presidential nominee, particularly for his foreign policy achievements during his presidency. However, he also questioned incumbent President Joe Biden’s shortcomings and said Biden would not cognitive test “because he would fail it.” “[I]t’s good to have a Republican nominee for president, Donald Trump, who’s ready to go on day one, can straighten out the world pretty quickly,” Graham said. “But here’s what I worry about, the whole world is watching. They saw the interview. They saw the debate, and how does...

First Lady Jill Biden’s ex-husband said he is getting “even more worried” about the state of the country after watching President Joe Biden’s interview with ABC’s George Stephanopoulos. “I wish he would have the cognitive test,” Bill Stevenson, who was married to Jill Biden from 1970 to 1975, told The Post Saturday. “George asked him about three or four times. It’s what the whole world is thinking about. I feel badly that this guy is someone who now can’t make a decision in the middle of the night.” “Watching…it was clear Joe Biden has deeper issues,” Stevenson added. “He was...

As new coronavirus variants gain traction across the United States, summer travelers are facing a familiar and tiresome question: How will the ever-mutating virus affect travel plans? In light of updated guidelines from the Centers for Disease Control and Prevention, the answers may be slightly different from those in previous years. Here’s what to know about traveling this summer if you’re worried about — or think you might have — Covid-19. Recent C.D.C. data show that Covid infections are rising or most likely rising in more than 40 states. Hospitalization rates and deaths, while low compared with the peaks seen...

In China Space Pioneer was performing a static fire test of the Booster for their Tianlong 3 rocket, a design which is a close copy of SpaceX's Falcon 9. Due to an engineering failure the rocket broke free of the test stand, flew under power for about 30 seconds before crashing back to Earth in a spectacular fireball.

HONOLULU (KHON2) — COVID numbers are up statewide according to the Department of Health (DOH). At least 1,180 new cases were diagnosed this week alone. But some people said finding a COVID test isn’t as easy as it used to be and neither is getting vaccinated. “I woke up realizing that I’m having symptoms. And so luckily, we had a test that we got on Amazon. So I took the test and it was positive,” said Murti Hower. He immediately went to the doctor to get medication.

Democrat California Gov. Gavin Newsom released an ad on Sunday showing Alabama police forcing young women to undergo pregnancy tests. “Alabama’s abortion ban has no exceptions for rape or incest. Now, Republicans are trying to criminalize young women’s travel to receive abortion care. We cannot let them get away with this,” Newsom said on X as he shared the video.

New urine-based test looks at 18 genes and was specifically developed to pick out those cancers that need immediate treatment over the slow-growing type. Researchers at the University of Michigan Rogel Cancer Center have developed a new urine-based test that addresses a major problem in prostate cancer: how to separate the slow-growing form of the disease unlikely to cause harm from more aggressive cancer that needs immediate treatment. The test, called MyProstateScore2.0, or MPS2, looks at 18 different genes linked to high-grade prostate cancer. In multiple tests using urine and tissue samples from men with prostate cancer, it successfully identified...

President Joe Biden “passes a cognitive test every day” due to the rigors of the job, said White House Press Secretary Karine Jean-Pierre on Wednesday, as she attempted to fend off reporters’ questions about Biden’s mental fitness. Jean-Pierre presided over a White House press briefing just hours after the president returned from his annual physical. She said that a cognitive test was not part of the annual checkup, despite concerns about Biden’s acuity. “If you look at what this president — he passes a cognitive test every day, every day, as he moves from one topic to another topic, understanding...

The White House says President Biden will not take a cognitive test — even after a damning report from his own Department of Justice highlighting his “poor memory” and voters expressing major concerns about his mental acuity. “The president proves every day [in] how he operates and how he thinks — by dealing with world leaders, by making difficult decisions on behalf of the American people — whether it’s domestic or national security,” White House press secretary Karine Jean-Pierre told reporters Monday, quoting from Biden’s physician, Dr. Kevin O’Connor. “That is how Dr. O’Connor sees it, and that is how...