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As we age, blood stem cells, the essential source of new blood cells in the body, can accumulate genetic mutations. Now, scientists have not only discovered the mechanism that fuels their unchecked growth but have also found a way to stop it. The study reveals that a common aging-associated mutation in the gene Dnmt3a boosts the power-generating function of mitochondria in blood stem cells. This mutation allows the cells to make copies of themselves more readily than normal and creates fertile ground for the development of clonal hematopoiesis, a condition that dramatically increases the risk of heart disease, blood cancers,...

The best time to view the Lyrids this year will be early morning on April 22. The best time to observe the Lyrids is in the predawn hours when the shower’s radiant is at its highest in the sky. However, be mindful that as the morning progresses, the radiant will continue to climb, but so will the approaching sunrise and the brightening skies, which will hinder visibility. The shower is known for its luminous dust trains which can be observed for several seconds according to NASA. The Lyrids are associated with Comet Thatcher, a long-period comet that orbits the sun...

China is doubling down: China has just announced that they will be pulling back from US private equity investments. Chinese state-backed funds are halting new investments in US PE firms due to government pressure. According to PE executives, funds like China Investment Corporation (CIC) have already begun withdrawing planned commitments. Chinese investors are also avoiding US-linked deals, even when managed by non-US based PE funds. Just 24 hours ago, China warned they would retaliate against countries that cooperate with the US in ways that compromise their interests. It's very clear what's happening here: China is seeking to isolate the US...

Anthropologist Richard Rudgley explores the history of the Celtic world and reveals the Celtic tradition to be a crucial part of what makes a Brit a True Brit. From Germany to the far west of Ireland, by way of Gaul, Pictish Scotland and England under Roman occupation, Rudgley takes a 5,000-mile journey of discovery that starts around 1,000 BC and ends in the present day. He uncovers remarkable archaeological evidence that puts a brand new light on the savagery and civilisation of an often misunderstood European culture. Where Did the Celts Really Come From? | 48:22 Our History | 883K...

President Donald Trump on Monday met with chief executives from three of the nation’s top retailers, who came to the White House to discuss how his sweeping tariff plans could impact their import-heavy business models. Walmart CEO Doug McMillon and Target chief executive Brian Cornell both attended, as did Home Depot CEO Ted Decker. A White House official told CNBC earlier Monday that a representative from Lowe’s would also be at the meeting. After the meeting concluded, an official told NBC News that no one from Lowe’s attended. After the meeting wrapped, the three companies issued nearly identical statements. “We...

They really are this evil. They stand up and fight for monsters but the Democrats never fight for America. IMAGE The sick illegal immigrant MS-13 gang member terrorists Democrats are so bent on defending have: — Raped and strangled a 20-year-old autistic woman to death in Maryland. — Hacked four people to death with machetes in a park on Long Island. — Kidnapped, sexually tortured and shot a teenage girl in Texas after she insulted their demon god. — Killed and mutilated a 17-year-old in Virginia, stabbing him sixteen times and cutting off his hands.

Don’t go by the defiant rhetoric, China is hurting and in deep trouble over Trump’s tariffsFor the purpose of writing this column, I had to do some research as I always do. What struck me was how effortlessly China is winning the battle of narratives. It’s all a little confusing. We are apparently in the middle of a trade war, caught in the crossfire as the world’s two largest economies slap each other with tariffs in an escalatory spiral with the Donald Trump administration imposing 145% levies on most Chinese goods this month. That’s more than a little concerning for...

Benny Johnson @bennyjohnson RFK Jr. casually walking around DC with a Saratoga bottle is aura. From Henry Bright 8:55 PM · Apr 21, 2025

A glamorous city known for sprawling mansions, boutique shops and glamor is at risk of becoming 'the next Detroit,' according to experts. Los Angeles is being rocked by an exodus of big budget TV and film production companies — long considered the backbone of the local economy. Detroit was once the center of America's auto production, but fell into decline when factories began to shut, triggering a major housing crisis. Now, some fear LA faces a similar threat. FilmLA reports that on-location production in the city fell by 22.4 percent in the first quarter of 2025 compared to the same...

This video will more than make your day. These two Australian twins were interviewed and gave their firsthand accounts of what happened when a stolen car crashed on Steve Irwin Way and the perp got out with a gun (peak Australia right here). There's no way @7NewsAustralia thought they could post this with the comments off and not have anyone say something.Is this clip farming? pic.twitter.com/ADp8nx9jfV— What’s News!? (@Whats_Newsss) April 21, 2025

Shortly after taking office, the Trump administration offered federal employees a deal many couldn’t refuse: resign voluntarily and receive full benefits and paid leave lasting until September.Demonstrators rally outside the U.S. Office of Personnel Management in Washington on Feb. 5, 2025. Nathan Howard/ReutersMore than 75,000 workers eventually accepted the Deferred Resignation Program, or buyout, which came as part of the administration’s broader efforts to shrink the size of the federal bureaucracy. Since the beginning of President Donald Trump’s second term, the government has already laid off hundreds of thousands of federal employees and contractors.As the federal government concludes a second...

WASHINGTON — House Republicans have asked Attorney General Pam Bondi to charge former New York Gov. Andrew Cuomo for making “criminally false statements” to Congress, citing “overwhelming evidence” that an audit he presided over had low-balled nursing home deaths during the COVID-19 pandemic. The House Oversight Committee re-upped the criminal referral after then-Attorney General Merrick Garland declined last year to prosecute Cuomo for allegedly triggering, helping to draft and reviewing a July 6, 2020, report that undercounted the total number of deaths in senior care facilities by 46%. “Andrew Cuomo is a man with a history of corruption and deceit,...

What a big surprise that a few leakers get fired and suddenly a bunch of hit pieces come out! They take anonymous sources from disgruntled former employees, and then they try to slash and burn people and ruin their reputations. NOT going to work with me, because we're changing the Defense Department, putting the Pentagon back in the hands of war fighters and anonymous smears from disgruntled former employees on old news doesn't matter.

Metformin, a widely used diabetes drug, could prevent a form of acute myeloid leukemia in people at high risk of the disease, a study in mice has suggested. Acute myeloid leukemia (AML) is an aggressive form of blood cancer that is very difficult to treat. Thanks to recent advances, individuals at high risk of AML can be identified years in advance using blood tests and blood DNA analysis, but there's no suitable treatment that can prevent them from developing the disease. In this study, Professor George Vassiliou investigated how to prevent abnormal blood stem cells with genetic changes from progressing...

The Illinois High School Association (IHSA) says it will continue to ignore a federal directive barring the participation of biological male athletes in high school girls’ sports. Previously, the State of Maine announced it would not comply with the directive, issued as an Executive Order by President Donald J. Trump in February, and now faces a federal lawsuit filed by the U.S. Department of Justice (DOJ). ISHA’s president, Dan Tully, claims that state law preempts the federal restriction and requires Illinois high schools to accommodate so-called transgender athletes, who are biological males, by allowing their participation in girls’ sporting events....

A new report from GlobalData, a data and analytics group, projects global nuclear power capacity will hit 494 GW by 2035. The group’s “Nuclear Power Market, Update 2025–Market Size, Segmentation, Major Trends, and Key Country Analysis to 2035” said capacity gains will be tied to advancements in deployments of small modular reactors (SMRs), along with the continuing worldwide shift to cleaner forms of energy. The report released April 21 said recent gains in nuclear power have been driven by moves toward more low-carbon baseload power. Measures promoting energy security, in addition to interest in decarbonization of industrial sectors, also is...

Yuppies of the world, unite! New York Times columnist David Brooks, calling for a “mass civic uprising” against Donald Trump: "We live in a country with catastrophically low levels of institutional trust. University presidents, big law firms, media organizations and corporate executives face a wall of skepticism and cynicism. If they are going to participate in a mass civic uprising against Trump, they have to show the rest of the country that they understand the establishment sins that gave rise to Trump in the first place… [that] this is not just defending the establishment; it’s moving somewhere new." You don’t...

April 21 (UPI) -- A brewery in Belgium swapped painted eggs for frothy brews when it celebrated Easter with the "World's Biggest Beer Hunt." The fifth annual Easter event at the Aywiers Gardens in Lasne, Belgium, saw over 1,000 registered hunters searching the grounds for 12,000 hidden bottles of Lutgarde beer. Hidden among the beers was a special golden bottle, which earned its finder a prize of his weight in beer. The event began Sunday with a chocolate egg hunt for children at noon, and the beer hunt then commenced at 12:30 p.m. A barbecue at 1:30 p.m. allowed the...

The Hennepin County Attorney’s Office has decided not to file criminal charges against a 33-year-old man accused of inflicting $21,000 in damage to six Teslas in Minneapolis over a few-day span. Instead, the office will file for Dylan Bryan Adams, of Minneapolis, to be entered into an adult diversion program meant for first-time, low level offenders. “Our main priorities are to secure restitution for the victims and hold Mr. Adams accountable,” said Hennepin County Attorney’s Office spokesman Daniel Borgertpoepping, in a statement. “As a result, we will file for pre-charge diversion to best facilitate both of those goals. This is...

Join with fellow FREEPERS to pray for AMERICA: For those in Authority in Government, Family, Military, Business, Healthcare, Education, Churches, and the Media.This is the confidence we have in approaching God: That if we ask anything according to His will, He hears us. (1 John 5:14)Religion Forum threads labeled *Prayer* are closed to debate of any kind.1 John 5:20 "And we know that the Son of God has come and has given us understanding, so that we may know him who is true; and we are in him who is true, in his Son Jesus Christ. He is the true...