Posted on 04/03/2019 11:35:30 AM PDT by Red Badger
With its pudgy body, tired eyes and hair loss, the lower mouse could easily be the father of the sprightly and alert animal nestling alongside.
But they are actually the same age, the result of extraordinary trials of drugs which are slowing down or even reversing the ageing process.
Scientists now believe that ageing itself is responsible for many major conditions such as Alzheimers, Parkinsons, arthritis, cancer, heart disease, and diabetes. And they think they have found a way to turn it off.
Anti-ageing drugs - dubbed senolytics - are currently being trialled in humans and unlike previous tests which have focussed on a single disease, these drugs work like a broad-spectrum antibiotic, preventing or alleviating most age-related illnesses and frailty.
Scientists at The Mayo Clinic, who first coined the term senolytics, already have six trials in humans under way and plan to start six more shortly. If successful, they estimate that drugs to slow down ageing could be ready within two years.
In mice, the drugs extend lifespan by 36 per cent, the equivalent of adding around 30 years to humans, and crucially the animals remained in good health.
Clinical geriatrician Dr James Kirkland, Director of the Robert and Arlene Kogod Center on Aging at Mayo Clinic, said: Most people dont want to live to 130 and feel like theyre 130 but they wouldnt mind living to 90 or 100 and feel like theyre 60. And now that can actually be achieved in animals.
Ageing itself is the highest risk factor for most of the chronic diseases. And if you get one age-related disease, youve got a huge chance of having several.
You tend to find older individuals who are completely healthy and are playing 18 rounds of golf a day, or theyve got three,five or 10 different conditions.
(Excerpt) Read more at uk.news.yahoo.com ...
But what really matters is how your health is. I look young but feel very old as a result of a wild youth.
One mouse to another: “There can be only one!”
From my experiences in the last 25 years, what sane person really wants to hang around very long????
Interestingly they say the point of Dasatinib plus Quercetin is to clean out senescent cells. If you do research on the term autophagy—you’ll find that fasting does the same thing.
after a day or two take some short and middle chain fatty acids plus curcuminm & black pepper and go into ketosis for a day. feel good.
Quercetin combined with Bromelain is good. Rutin is also very good.
The people who are 79 that want to live to be 80?
[from “Sleeper”]
Dr. Melik: Well, he’s fully recovered, except for a few minor kinks.
Dr. Orva: Has he asked for anything special ?
Dr. Melik: Yes, this morning for breakfast. He requested something called wheat germ, organic honey and tiger’s milk.
Dr. Orva: [ laughs ] oh, yes. Those were the charmed substances that some years ago were felt to contain life-preserving properties.
Dr. Melik: You mean there was no deep fat ? No steak or cream pies or hot fudge ?
Dr. Orva: Those were thought to be unhealthy, precisely the opposite of what we now know to be true.
What color does it turn you?
bookmark
How about not eating like crap, exercising just a little, and keeping your head busy?
That’s a good start.
Maybe fasting works for you but, like caloric restriction, it is not easy or pleasant. I suppose that one could get used to it, but you therefor deny yourself some of the most pleasurable things in life. I think that this is the point of developing drugs, or discovering natural substances, that mimic the effects produced during fasting/caloric restriction - to let us eat our cake and have it, too.
Meanwhile, scientists have cured cancer in mice dozens of times over the years.
Just what we need, healthier rats
to let us eat our cake and have it, too.
.......
there’s no getting around the problem of sugar.
Modern research is pointing to sugar induced inflammation to be responsible for most of the maladies of modern civilization.
The body can burn either fat or sugar. Its turning out to be far healthier to burn fat.
Meanwhile, scientists have cured cancer in mice dozens of times over the years.
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the result of that work is that a lot more people are surviving cancer than in years past.
Sounds like exercise and intermittent fasting really help. That is good.
........
also replace the carbs and sugars with fat. the body can burn either sugar or fat. Turns out its much healthier to burn fat.
Growing old, by definition, is not a disease, it is natural. What defines a drug or med device is to (basically) treat or fix a negative issue.
The same reason why birth control was not covered by insurance but viagra was covered.
The rules have been changed and by treating many coming medical ailments by reversing the aging process, the path has been cleared of obstacles.
Get gel caps for the powder.
Reality? I told Mrs WBill that when she turned 40, I was "going to trade her in on two 20's. Hahaha."
She replied, "Great. I could use some help around the house."
Game, set and match to my lovely wife. I know when I've been aced.
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