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A study of more than 300,000 adults in the United Kingdom has found support for a causal relationship between vitamin D deficiency and mortality. These findings suggest a need for public health strategies to maintain healthy levels of vitamin D in the population. Low vitamin D status has been linked to increased mortality, but mortality in the context of vitamin D deficiency remains unclear. Randomized controlled trials either fail to recruit people with severe deficiency or, because of ethical reasons, are prevented from doing so. Researchers conducted a nonlinear mendelian randomization study of 307,601 participants in the U.K. Biobank to...

A team of researchers located at Helmholtz Munich reports on a novel function of vitamin K, which is generally known for its importance in blood clotting. The researchers discovered that the fully reduced form of vitamin K acts as an antioxidant efficiently inhibiting ferroptotic cell death. Ferroptosis is a natural form of cell death in which cellular iron plays an important role and which is characterized by the oxidative destruction of cellular membranes. In addition, the team identified FSP1 as the warfarin-insensitive enzyme reducing vitamin K, the identity of which had been postulated but remained unknown for more than half...

Pantothenate acid, also known as vitamin B5, stimulated the production of brown fat in both cell cultures and mice, a new study finds. "We identified [pantothenate acid] as an effective [brown fat] activator that can prevent obesity and may represent a promising strategy for the clinical treatment of obesity and related metabolic diseases," the researchers wrote. Unlike the more common white fat, brown fat burns calories to produce heat. Under particular conditions, white fat can be converted to brown fat. Scientists have been investigating the behavior of brown fat and methods of converting white fat in hope of finding treatments...

Scientists Create Tomatoes Genetically Engineered To Boost Vitamin D. They used gene editing to enhance the production of vitamin D3 in tomatoes.

A study investigating the impact of vitamin D on gene expression has found significant differences between vitamin D2 and vitamin D3 supplements. The findings, published in the journal Frontiers in Immunology, indicate vitamin D3 may be more effective at strengthening the immune system compared to vitamin D2. Vitamin D generally comes in two main forms: ergocalciferol (vitamin D2) and cholecalciferol (vitamin D3). Prior research has established vitamin D3 supplements are much more effective at raising a person’s blood levels of vitamin D. However, it is unclear whether there is any functional differences to human health between the two types of...

In April 2005, a virulent strain of influenza hit a maximum-security forensic psychiatric hospital for men that’s midway between San Francisco and Los Angeles. John J. Cannell, a psychiatrist there, observed with increasing curiosity as one infected ward after another was quarantined to limit the outbreak. Although 10 percent of the facility’s 1,200 patients ultimately developed the flu’s fever and debilitating muscle aches, none did in the ward that he supervised. WINTER WOES. Cold-weather wear and the sun’s angle in the winter sky limit how much ultraviolet light reaches the skin. This can add up to a deficiency in production...

Sepsis, an infection that kills millions worldwide each year and is the third leading cause of death in the United States, may have finally met its match. Paul Marik, the EVMS Foundation Distinguished Professor in Internal Medicine, Professor of Internal Medicine and Chief of Pulmonary and Critical Care Medicine, believes he has developed a cure for the life-threatening infection. His treatment breakthrough promises to revolutionize sepsis care and produce results that are nothing short of astonishing. Vitamin C is often used intravenously as part of a treatment for cancer. Hydrocortisone is used to relieve inflammation and for a variety of...

High doses of vitamin C injected into the blood stream could help treat cancer, new research from scientists suggests. Injecting patients with a dose 1,000 times higher than the recommended level could target tumour cells and make radiation and chemotherapy more effective. Scientists gave eleven brain cancer sufferers regular dosages of vitamin C every week for nine months while receiving typical radiotherapy and chemotherapy. Tests showed the extra vitamin – usually found in oranges, green vegetables, broccoli and strawberries – made cancer cells more susceptible to treatment. It also appeared to be safe, producing mild side effects such as frequent...

MONDAY, April 4, 2016 -- Regular doses of vitamin D3 may improve heart function in heart failure patients, a new British study suggests. "These findings could make a significant difference to the care of heart failure patients," said study leader Dr. Klaus Witte, from the University of Leeds School of Medicine. "It is the first evidence that vitamin D3 can improve heart function of people with heart muscle weakness -- known as heart failure."

Vitamin D ...the researchers found that adults who took vitamin D supplements daily lived longer than those who didn't. Probiotics ...they're useful in very specific circumstances, but it's not necessary to continually take them on a daily basis. Zinc ...the mineral significantly reduced the duration of the cold, and also made symptoms less severe. Niacin ...Also known as vitamin B3, niacin is talked up as a cure for all sorts of conditions (including high cholesterol, Alzheimer's, diabetes and headaches) but in most of these cases, a prescription-strength dose of niacin has been needed to show a clear result. At over-the-counter...

Researchers say vitamin E might slow the progression of mild-to-moderate Alzheimer's disease -- the first time any treatment has been shown to alter the course of dementia at that stage. In a study of more than 600 older veterans, high doses of the vitamin delayed the decline in daily living skills, such as making meals, getting dressed and holding a conversation, by about six months over a two-year period. Vitamin E did not preserve thinking abilities, though, and it did no good for patients who took it with another Alzheimer's medication. But those taking vitamin E alone required less help...

Nicotinamide, commonly known as vitamin B3, may help the innate immune system kill antibiotic-resistant staph bacteria, the so-called "superbugs". In lab work done with mice and human blood, researchers found high doses of the vitamin increased the ability of immune cells to kill the bacteria by 1,000 times.The discovery opens the door to a new arsenal of tools for dealing with antibiotic-resistant bacterial infections, such as those caused by methicillin-resistant S. aureus or MRSA, that have killed thousands of people around the world. They are increasing in hospitals and nursing homes, and also rising in prisons, among athletes, people in...

DALLAS - Walking is just fine with 58-year-old Mary Cecil, who used to be an avid runner. "I was running and I started feeling pain in my left leg, and it was also tender when I slept on that side," she said. Cecil suspected a shin splint or pulled muscle. A bone scan, however, revealed a rare and aggressive tumor called dedifferentiated chondrosarcoma. The bone cancer is virtually unstudied. According to limited information, only one in 10 diagnosed with it survive two years. "Very scary," recalled Cecil of how she felt upon learning of the diagnosis. "The world just turned...

Medical quotes "We did the best we could... We can't recommend Chiropractic care because we 'don't know' what kind of harm they may cause. Research shows that supplements are dangerous. Research shows that drugs are effective and 'well tolerated' The medical profession deserves the public's trust" and they believe every word they say! Philosophy matters. Conservative, natural care has actually been defined by MDs as doing nothing. If you believe that drugs and surgery are the only solutions, then, what else do you have?

John J. Cannell, M.D writes that he receives numerous questions from individuals who ask, "My doctor prescribed Drisdol, is that OK?" Drisdol is vitamin D2 in a form that doctors write prescriptions for. Sun exposure does not produce vitamin D2 in the body, the vitamin is produced by plant matter and irradiating fungus. When consumed, numerous metabolic forms of D2 can be traced in the body. According to some studies, vitamin D3, which is produced by the skin, is more powerful, hence more effective at raising blood levels compared with vitamin D2, however, some studies say they are equal. Few...

Having low vitamin D levels may increase a person's risk of developing Parkinson's disease later in life, say Finnish researchers. Their study of 3,000 people, published in Archives of Neurology, found people with the lowest levels of the sunshine vitamin had a three-fold higher risk. Vitamin D could be helping to protect the nerve cells gradually lost by people with the disease, experts say. The charity Parkinson's UK said further research was required. Parkinson's disease affects several parts of the brain, leading to symptoms like tremor and slow movements. 30-year study The researchers from Finland's National Institute for Health and...

Vitamin C could be used to overcome hurdles in creating stem cells for treating human diseases, scientists believe. The vitamin boosts the reprogramming of adult cells to give them the properties of embryonic stem cells. Scientists who made the discovery believe it may help them overcome long-standing problems in creating the reprogrammed cells, called induced pluripotent stem cells (iPSCs).

The claims have been sensational. Martin Mittelstaedt checks up on the research behind the hype ### In the summer of 1974, brothers Frank and Cedric Garland had a heretical brainwave. The young epidemiologists were watching a presentation on death rates from cancer county by county across the United States. As they sat in a lecture hall at Johns Hopkins University in Baltimore looking at the colour-coded cancer maps, they noticed a striking pattern, with the map for colon cancer the most pronounced. Counties with high death rates were red; those with low rates were blue. Oddly, the nation was almost...

CORVALLIS, Ore. – A string of recent discoveries about the multiple health benefits of vitamin D has renewed interest in this multi-purpose nutrient, increased awareness of the huge numbers of people who are deficient in it, spurred research and even led to an appreciation of it as "nature's antibiotic." On issues ranging from the health of your immune system to prevention of heart disease and even vulnerability to influenza, vitamin D is now seen as one of the most critical nutrients for overall health. But it's also one of those most likely to be deficient – especially during winter when...

BOSTON — The high prevalence of vitamin D deficiency found in a cohort of healthy children in a sunny Southwestern climate has prompted a call by the study's investigators for generalized routine screening of vitamin D levels among all children. In a study designed to assess vitamin D levels in children living in a region with year-round sunshine and to compare vitamin D levels in children with vague musculoskeletal pain with those of children without pain, Dr. Elizabeth A. Szalay and her colleagues at the University of New Mexico Hospital in Albuquerque retrospectively studied the serum 25-hydroxyvitamin D (25[OH]D) levels...