Posted on 10/25/2022 9:09:23 PM PDT by ConservativeMind
A study of more than 300,000 adults in the United Kingdom has found support for a causal relationship between vitamin D deficiency and mortality. These findings suggest a need for public health strategies to maintain healthy levels of vitamin D in the population.
Low vitamin D status has been linked to increased mortality, but mortality in the context of vitamin D deficiency remains unclear. Randomized controlled trials either fail to recruit people with severe deficiency or, because of ethical reasons, are prevented from doing so.
Researchers conducted a nonlinear mendelian randomization study of 307,601 participants in the U.K. Biobank to assess genetic evidence for the causal role of low vitamin D status in mortality. The authors evaluated measurements of participants' 25-hydroxyvitamin D (25-(OH) D) and other genetic data. They also recorded and analyzed both all-cause and cause-specific mortality data. Over a 14-year follow up period, the authors found that the risk for death decreased significantly with increased vitamin D concentrations, and the strongest effects were seen for persons in the severe deficiency range. They note that recent estimates for the prevalence of severe deficiency range from 5 to 50 percent of the population, with rates varying by geographic location and population characteristics.
According to the authors, their study affirms the potential for a notable effect on premature death and the continued need for efforts to abolish vitamin D deficiency.
(Excerpt) Read more at medicalxpress.com ...
Pretty sure my mortality risk is 100%, be it today or 20 years from now
Got milk?
I caught a video about vitamin D3 (20M units a day) being a natural steroidal anti-inflammatory.
Any info on that?
Its NOT unclear as the article says.
Vitamin D is a master hormone that affects and works on 29,000 genes in the human body.
Its so important we make it by exposure to sunlight. Because its used by so, so many processes in the body.
Since few of us get enough sunlight, my wife and I take 5,000 iu of Vitamin D3 and 50 mg Zinc daily as our Covid preventative. Seems to be effective. No shots.
We all need 15 minutes a day in sunshine WITHOUT sunscreen. That should do the trick (longer if in northern states like MN or ND etc).
Vitamin D is a master hormone that affects and works on 29,000 genes in the human body.
Its so important we make it by exposure to sunlight. Because its used by so, so many processes in the body.
_____
I get sunlight every day as I take a walk. Usually with my shirt off to get/manufacture D3.
But the older you get, you cannot trust getting D3 by sunlight only. Your D3 conversion process diminishes. So I take 10-20 thousand IU D3 daily. At this level K2 is a must and so is a magnesium supplement such as magnesium glycinate.
No. Take D3 too. 5000 iu daily.
A year or so ago I saw some doctor talking about Covid, and health in general. IIRC he said there were 5 things essential to a healthy body.
1) Vitamin D
2) Vitamin D
3) Vitamin D
4) Vitamin D
5) Exercise
I’m guessing on the exercise one - maybe it was diet??
Same doses ....
So I should get sun at least 15 minutes a day
Big Med's just having all kinds of revelations, ain't they?
You should get at least 15 minutes a day, and in winter and north of the latitude of Philadelphia, even more. Also if you are dark skinned. In fact the difficulty of dark skin allowing Vitamin D formed in the skin to move into the body is probably the reason about 2.5 times more people with dark skin have been dying of Covid. One study of black men hospitalized with Covid found that 80% were very deficient in Vitamin D. Why doesn’t the CDC or other appropriate agency warn people of color they need more Vitamin D than light skinned people, or are they indifferent to letting Negroes and American Indians die in larger numbers?
A blood sample might confirm your assumption.
In my opinion, the “15 minutes of sunlight” rule is just guessing.
I carefully read the material at the top of this post, and also the link for the article quoted. I could not find your sentance about 29,000 genes affected. The figure I have encountered on several occasions is that D affects about 10% of our genes, which is about 2,000 genes Plenty enough to make evaluating our personal need for enough Vitamin D to influence all the genes that need it.
It is important to note this study was done in UK, which uses the measure for blood Vitamin D as bmol/L (nanomol per liter). In the US we use the measure ngm/mL (nanograms per mililiter). In comparieng studies in the US with those overseas divide nmol/L by 2.5 to get ngm/mL. Thus 25 nmol/L equals 10 ngm/mL. According to US govt authorities this is a dividing line between deficient and severely deficient. The 50 nmol/L figure equals 20 ngm/mL. US authorities consider this the dividing line between deficient and normal. US endochrine professionals consider this figure is too low. They consider figures between 20 ngm/ml and and 29 ngm/mL as insufficient. And 30 ngm/mL and above as normal. My health provider Kaiser Permanente considers between 50 and 80 ngm/mL as OPTIMUM.
The study below performed in Turkey and published Nov. 2021 Was valuable for several reasons. First of all it used the original Dr. Zelenko 3 part early Covid treatment of zinc, HCQ and Azithromycin. It added Vitamin D3 and Vitamin C in 2 strengths. A gram (1000 mg) a day of C for the controls, and much higher amount of C given IV (intravenously) for test subjects. The goal was to see if IV C would reduce time spent in the hospital. It did, spectacularly, compared with $3000 a treatment Remdesivir.
cureus.com/articles/76496-therapies-to-prevent-progression-of-covid-19-including-hydroxychloroquine-azithromycin-zinc-and-vitamin-d3-with-or-without-intravenous-vitamin-c-an-international-multicenter-randomized-trial
Then the doctors examined the blood tests given to study participiants before the trial began. They were ASTONISHED to discover that NOT ONE patient had an optimum level of blood Vitamin D. They were using the relatively low figure of 30 ngm/mL (75 nmol/L) or more as their measure of OPTIMUM. Only 3 of almost 240 subjects were insufficient, and the rest divided between deficient and very deficient. The one person who died had 3 ngm/mL.
Thus I think it is very reasonable to say, test your blood, talk with your doctor, and get your BLOOD VITAMIN D LEVEL TO THE OPTIMUM LEVEL. This should make it unlikely you will end up in a hospital. At weight 145 lbs, and 18 months of taking 2000 IU of D in summer, and increasing gradually to 5000 IU the 4 winter months, when KP tested me I was in the OPtIMUM range at 66 ngm/mL.
Yes, particularly in winter, it’s good to take a walk in the sun around noon every day.
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