Skip to comments.Vitamin B5 activates brown fat, aids weight loss in mice
Posted on 07/28/2022 9:43:38 PM PDT by ConservativeMind
Pantothenate acid, also known as vitamin B5, stimulated the production of brown fat in both cell cultures and mice, a new study finds.
"We identified [pantothenate acid] as an effective [brown fat] activator that can prevent obesity and may represent a promising strategy for the clinical treatment of obesity and related metabolic diseases," the researchers wrote.
Unlike the more common white fat, brown fat burns calories to produce heat. Under particular conditions, white fat can be converted to brown fat. Scientists have been investigating the behavior of brown fat and methods of converting white fat in hope of finding treatments for obesity.
The research team selected vitamin B5 from among compounds that showed potential because of its safety and ease of access. They treated cell cultures of human tissue with vitamin B5. After six days, the cells showed a rise in a number of markers that indicate an increase in mitochondria—a part of the cell that burns calories and which brown fat has in greater quantity than white fat. Staining the tissue also demonstrated an increase in brown fat.
They then fed male mice a high-fat diet and treated them for 11 weeks with either vitamin B5 or a saline solution as a control. The vitamin B5-treated high-fat mice showed reduced fat not only overall but, specifically, less fat just under the skin and in the liver compared to those not given vitamin B5. The two groups had a comparable amount of muscle, a sign the weight loss was from reduction in fat.
In addition to fat loss, the vitamin B5-treated mice also showed significant reduction in fatty liver disease, lower blood insulin levels and improved glucose tolerance.
"[Pantothenate acid] has therapeutic potential for treating obesity and type II diabetes," researchers conclude.
(Excerpt) Read more at medicalxpress.com ...
In a Japanese study, pantethine reversed fatty liver, and also did so in a relative who took it, with before and after MRIs and ultrasounds.
The amount used in the study was 600 mg for six months. This relative had it fully resolve in five.
Thanks for the tip. I’m having a problem with weight gain as I get older. The things that always worked in the past to lose weight just aren’t doing it for me. I’m 68 and about ready to just give up and spend the rest of my life being 20+ lbs overweight. 😖
I want to look into this. I have five stubborn pounds that I haven’t been able to get off for a year. I’m working at it, but nothing seems to be helping. I realize I may be at the weight my body thinks is best, but I just want to lose a little more. I have some clothes I really want to fit into. I wore them a few years ago, and I felt great. So I think it’s possible but I don’t know what’s in my way anymore. Maybe this will help?
Vitamins and food supplements will not make your body stronger. I am 82 and have zero health problems and fit into my wedding suit from year 1992. I do treadmill 5-6 times every week. Just walk at good pace with wrist weights of 1 lb each. I swing arms with wrist weights. Keeps me fit, athletic and flexible. Try it. Start slow and work up to 25 minutes routine. Benefits are amazing.
Would that be 600 mg once a day for 6 months?
Thats not whzt people take vitamins and supplements for.
You take them because you aren’t getting enough nutrients from other sources like food and sunlight. Most people don’t eat well and even if you try certain foods grown in different soils around the country are deficient in various minerals. If all your food is processed and fast you are getting much less good building blocks and you will need supplementation.
I wear 2 lb ankle weights while I walk on the treadmill for 30-40 minutes using a 4% grade at 3.2 mph. I do that 4-5 times a week. I try to keep my caloric intake under 1500 which is the correct BMR for my height and weight. The number on the scale still keeps creeping up, which is very frustrating, especially since this weight loss regimen used to work in the past.
I’ve tried intermittent fasting and saw no results. However, I’m a night owl and apparently that makes a difference as far as my metabolism is concerned. That’s the only explanation I can come up with. 😖
I’ve been using vitamin B4 for weight loss. As in “B4 I order my meal I remember how much weight I want to lose”.
The effects of pantethine on fatty liver and fat distribution (56% study participants eliminated fatty liver in six months):
300 mg twice a day is what they used, as I recall.
Just what we need, slim, muscular and healthy mice!
Top 10 Vitamin B5 Foods
Vitamin B5 foods come from both plant and animal food sources.
What foods have B vitamins? Certain meats, vegetables, grains, legumes, eggs and dairy products contain B5 as well as other essential B vitamins.
Here are some of the very best choices when it comes to upping your dietary intake of vitamin B5 foods.
1. Chicken Liver — 3 oz: 8.3 milligrams (83 percent DV)
Chicken, duck and beef liver are true superfoods. When it comes to foods with B vitamins, liver tops the charts.
Chicken liver is impressively high in vitamin B5 as well as B12 and is an excellent food for preventing anemia. When you buy liver, you just want to make sure that the animals are grass-fed, free-range and pasture-raised.
2) Sunflower seeds — 3 oz: 6 milligrams (60 percent DV)
Sunflower seeds make for such an easy and tasty snack that is loaded with vitamin B5 as well as protein and vitamin E. Research has linked eating foods high in vitamin E to a decreased risk of coronary heart disease.
3) Avocados — 1 fruit: 2 milligrams (20 percent DV)
Looking to get a healthy dose of dietary vitamin B5 as well as vitamin B6, not to mention healthy monounsaturated fats? Then avocado is the perfect choice.
Several studies have looked at the consumption of avocados and the effects on heart health. The results have consistently showed positive heart-healthy effects on lipid profiles (total cholesterol, LDL, HDL and triglycerides).
4) Portobello Mushrooms — 1 cup sliced: 1.9 milligrams (19 percent DV)
Mushrooms like the portobello are an excellent dietary source of B vitamins. The portobello mushroom is also very rich in potassium, which is key to electrolyte balance and hydration.
Potassium is also a key nutrient when it comes to keeping blood pressure levels in a healthy range.
5) Salmon — 3 oz: 1.6 milligrams (16 percent DV)
Wild-caught salmon is one of the best animal proteins you can eat. It’s high in B5 and so many other nutrients.
It’s also one of the best sources of omega-3 fatty acids, which are highly anti-inflammatory. Consuming anti-inflammatory food sources like wild-caught salmon on a regular basis can really boost health since inflammation is known to be at the root of most diseases.
6) Lentils — 1 cup: 1.3 milligrams (13 percent DV)
Lentil nutrition is really impressive. Not only are lentils high in B vitamins, but they are also a rich source of folate and manganese.
With 18 grams of protein per one-cup serving, lentils are one of the top sources of plant-based protein. If you don’t eat meat, lentils are an especially smart choice for your diet.
7) Corn — 1 cup: 1.2 milligrams (12 percent DV)
Corn — organic, non-GMO corn to be more specific — is a good dietary source of vitamin B5, antioxidants, fiber and complex carbohydrates. Corn has been a staple crop for thousands of years.
Nowadays, there is so much GMO corn that we have to make sure we choose our corn carefully.
8) Sun-dried tomatoes — 1 cup: 1.1 milligrams (11 percent DV)
Sun-dried tomatoes are basically ripe tomatoes minus the water content. Tomatoes and sun-dried tomatoes contain a compound called lutein, which along with zeaxanthin have been shown to decrease the risk for major eye issues like cataracts.
9) Eggs — 3 oz: 0.9 milligrams (9 percent DV)
Eggs are rich in vitamin B5 and are also a very affordable source of protein. When you opt for free-range eggs, you get even more of essential nutrients like beta-carotene and omega-3s but less cholesterol.
10) Cauliflower — 1 cup: 0.7 milligrams (7 percent DV)
Cauliflower is a type of cruciferous vegetable, and consumption of this class of vegetables has been linked to cancer prevention.
As a cruciferous vegetable, cauliflower is helpful to digestion and detoxification because of its sulfur-containing glucosinolates, which support nutrient absorption and waste removal.
It looks like 10mg is the daily value
FIVE AND TWO
fast two out of five days....
That seems to help my weight control
Yeah, I’ve been taking this but only at 300mg@day. I’ll have to up that as I do have a gut.
Isn’t that racist?
Should be renamed “not honky fat”’.
Get your hormones checked
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