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A quick and pain-free scan of the human eyeball could one day help doctors identify 'fast agers', who are at greater risk of early mortality. Getting older obviously has an impact on everybody's body, but just because two people have the same number of years under their belt doesn't mean they are physically declining at the same rate. Looking deep into a person's eyes could be a far better way to measure their true biological age, and this could provide a glimpse into the future health of patients. A machine learning model has now been taught to predict a person's...

* New research indicates the hard limit on human life is 150 years. * The main factor limiting our lifespan is a loss of the ability to bounce back after a setback, called "physiological resilience." * Even without major health issues, like cancer, your body will eventually run out of energy to help recover from even minor challenges. =========================================================================================== Even if you somehow manage to make it through decades of old age without a single major health issue—evading cancer, heart disease, diabetes, and so on—scientists say there's a ceiling on how long you can extend your life, throwing cold water...

Key to living past 100 may hinge on your gut health, study of centenarians shows TOKYO — Centenarians have unique gut bacteria that enables them to live to a ripe old age, according to new research. Scientists in Japan say this unique gut makeup fuels bile acids that protect against disease. The discovery could lead to yogurts and other probiotic foods that increase longevity. “In people over the age of 100, an enrichment in a distinct set of gut microbes generate unique bile acids,” says lead author Professor Kenya Honda of Keio University in a statement per South West News...

Researchers have found that omega-3 levels in blood erythrocytes are very good mortality risk predictors. The study used data from a long-term study group, the Framingham Offspring Cohort, which has been monitoring residents of this Massachusetts town, in the United States, since 1971 and concludes that, 'Having higher levels of these acids in the blood, as a result of regularly including oily fish in the diet, increases life expectancy by almost five years.' Researchers have found that omega-3 levels in blood erythrocytes (the so-called red blood cells) are very good mortality risk predictors. The study concludes that "Having higher levels...

“There are huge strides being made in aging biology” that point to ways that we can potentially slow the aging process, says Steele, 35, whose research focuses on the ways that the body ages at a cellular level. “We have loads and loads of different ways in the lab to slow down and reverse this process.”

The pandemic isn’t stopping family and friends from celebrating a Palmer Twp. man’s milestone birthday. “It’s unbelievable!” Charlie Volpe exclaimed. On Sunday, a parade of cars donned with balloons and signs drove by to surprise Volpe. The World War II veteran is celebrating a milestone: his 100th birthday. “I’ve had a lot of surprises but not like this! This is really fantastic,” Volpe said. Volpe insists there’s one key to living a long and fulfilling life: “My family and my grandchildren. I always told them that Pop is going to live for a long time for you guys,” he said....

As we age, our skin is one of the first places it shows. But skin aging is caused by a number of things beyond just the years we're alive for. "Skin aging is the result of both intrinsic biologic processes that contribute to chronologic aging, as well as extrinsic factors such as ultraviolet (UV) radiation, smoking, pollution, and poor nutrition," says Jacquelyn Sink, MD, a dermatologist at Northwestern Medicine Central DuPage Hospital. While it's important to wear a hat outside and avoid smoking, another preventative anti-aging skincare measure is to eat a healthy diet. "As with all aspects of our...

The researchers exposed 35 healthy individuals aged 64 or over to a series of 60 hyperbaric sessions over a period of 90 days...The findings indicated that the treatments actually reversed the aging process in two of its major aspects: The telomeres at the ends of the chromosomes grew longer instead of shorter, at a rate of 20%-38% for the different cell types; and the percentage of senescent cells in the overall cell population was reduced significantly – by 11%-37% depending on cell type...The paper was published in Aging on November 18, 2020.

From processed meats to high fructose corn syrup, these are all the items linked to early death. Though it may come as a surprise to some, not all "processed" foods are created equal. There are minimally processed foods, such as canned vegetables and frozen meats, and then there are highly processed foods, such as mass-produced, store-bought breads, TV dinners, and other items that come packed with saturated fats, added sugars, and practically zero fiber. (For more on those, see our complete list of the 100 Unhealthiest Foods on the Planet.) "Nutritionally speaking, minimally processed foods generally offer similar nutritional benefits—vitamins,...

A massive study published in 2020 found evidence that blood iron levels could play a role in influencing how long you live. It's always important to take longevity studies with a big grain of salt, but the research was impressive in its breadth, covering genetic information from well over 1 million people across three public databases. It also focused on three key measures of ageing: lifespan, years lived free of disease (referred to as healthspan), and making it to an extremely old age (AKA longevity). Throughout the analysis, 10 key regions of the genome were shown to be related to...

Cellular reprogramming can reverse the aging that leads to a decline in the activities and functions of mesenchymal stem/stromal cells (MSCs). This is something that scientists have known for a while. But what they had not figured out is which molecular mechanisms are responsible for this reversal. A study released today in STEM CELLS appears to have solved this mystery. It not only enhances the knowledge of MSC aging and associated diseases, but also provides insight into developing pharmacological strategies to reduce or reverse the aging process. The research team, made up of scientists at the University of Wisconsin-Madison, relied...

The researchers found that a unique protocol of treatments with high-pressure oxygen in a pressure chamber can reverse two major processes associated with aging and its illnesses: the shortening of telomeres (protective regions located at both ends of every chromosome) and the accumulation of old and malfunctioning cells in the body...The clinical trial was conducted as part of a comprehensive Israeli research program that targets aging as a reversible condition.

Every time a cell inside your body replicates, a slither of your youth crumbles to dust. This occurs via the shortening of telomeres, structures that 'cap' the tips of our chromosomes. Now, scientists in Israel say they've been able to reverse this process and extend the length of telomeres in a small study involving 26 patients. The participants sat in a hyperbaric oxygen chamber for five 90 minutes sessions per week over three months, and as a result, some of their cell's telomeres were extended by up to 20 percent. It's an impressive claim - and something many other researchers...

Summary: Scientists have identified synergistic cellular pathways for longevity that amplify lifespan fivefold in C. elegans, a nematode worm used as a model in aging research. The increase in lifespan would be the equivalent of a human living for 400 or 500 years, according to one of the scientists. Share: Scientists at the MDI Biological Laboratory, in collaboration with scientists from the Buck Institute for Research on Aging in Novato, Calif., and Nanjing University in China, have identified synergistic cellular pathways for longevity that amplify lifespan fivefold in C. elegans, a nematode worm used as a model in aging research....

With a combined age of 211 years, one couple in Austin, Texas, has been named the oldest living couple in the world, according to Guinness World Records. John Henderson is 106 and his wife, Charlotte, is 105. The Hendersons have a love story that has quite literally stood the test of time. On December 15, they will celebrate 80 years of marriage. The two met in class at The University of Texas in 1934. Charlotte was studying to become a teacher, while John was a guard for the football team. They married in 1939 during the Great Depression and spent...

Highly educated “experts” rule today’s advanced societies, but their advice on how the rest of us should live – often enforced by government coercion –is increasingly exposed as premature at best and mistaken, incomplete, ignorant, or fraudulent at worst.Yet another bit of diet advice from “experts” is turning out to be an exploding cigar. High cholesterol particularly LDL cholesterol has been demonized for allegedly bringing on heart attack deaths. But an intriguing analysis of data published in Medium.com seems to show that total mortality is enhanced by high cholesterol levels, even LDL cholesterol. As author P.D. Mangan writes: …...

We are all ageing – it’s a fundamental fact of life. But the majority of us are totally unprepared for what lies ahead. Yes, we may have pensions in place and follow the basics of a healthy lifestyle but can you truly say that you have thought deeply about all aspects of your later life? The good news is I’m here to tell you that getting older doesn’t have to mean it all goes downhill. In fact, it can be the start of a whole new adventure if you are prepared for a major rethink about how you can make...

In October 2014, Ezekiel Emanuel published an essay in the Atlantic called “Why I Hope to Die at 75.” Because Emanuel is a medical doctor and chair of the University of Pennsylvania’s department of medical ethics and health policy, as well as a chief architect of Obamacare, the article stirred enormous controversy. Emanuel vowed to refuse not only heroic medical interventions once he turned 75, but also antibiotics and vaccinations. His argument: older Americans live too long in a diminished state, raising the question of, as he put it, “whether our consumption is worth our contribution.” Emanuel was born into...

With its pudgy body, tired eyes and hair loss, the lower mouse could easily be the father of the sprightly and alert animal nestling alongside. But they are actually the same age, the result of extraordinary trials of drugs which are slowing down or even reversing the ageing process. Scientists now believe that ageing itself is responsible for many major conditions such as Alzheimer’s, Parkinson’s, arthritis, cancer, heart disease, and diabetes. And they think they have found a way to turn it off. Anti-ageing drugs - dubbed ‘senolytics’ - are currently being trialled in humans and unlike previous tests which...

When it comes to regeneration, some animals are capable of amazing feats. If you cut off a salamander’s leg, it will grow back. When threatened, some geckos drop their tails to distract their predator, only to regrow them later. Other animals take the process even further. Planarian worms, jellyfish, and sea anemones can actually regenerate their bodies after being cut in half. Led by Assistant Professor of Organismic and Evolutionary Biology Mansi Srivastava, a team of researchers is shedding new light on how animals pull off the feat, along the way uncovering a number of DNA switches that appear to...