Perfluoroalkyl and polyfluoroalkyl substance (PFAS) exposure is associated with later occurrence of inflammatory bowel disease (IBD), according to a research letter. Manasi Agrawal, M.D. and colleagues examined the association of PFAS mixture concentrations in prediagnostic serum in patients with adult-onset IBD participating in a pilot study within the preclinical Proteomic Evaluation and Discovery in an IBD Cohort of Tri-service Subjects study. The analysis included military personnel with Crohn disease (CD), those with ulcerative colitis (UC), and age-, sex-, and race-matched healthy controls (25 in each group). The researchers found that estimated mean concentrations in the study population were 5.19 µg/L...