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Keyword: brainaging

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  • Deep learning uncovers gene targets and potential drugs to slow brain aging

    03/20/2025 8:01:17 PM PDT · by ConservativeMind · 6 replies
    Medical Xpress / Science Advances ^ | March 16, 2025 | Sanjukta Mondal / Fan Yi et al
    In a new study, scientists analyzed MRI data stored at the UK Biobank and identified seven genes responsible for fast biological brain aging and 13 existing drugs that can target those genes. Slowing the aging process is a powerful strategy to prevent many diseases and enhance longevity. A crucial parameter in brain health research is the brain age gap (BAG), which is the difference between a person's estimated biological brain age and their chronological age. The brain age gap is also a reliable biomarker (or proxy) for studying brain health. While the effects of the BAG are well explored, identifying...
  • In-depth review reveals dietary lipid intervention as potential strategy to prevent brain aging (Phosphatidylcholine, phosphatidylserine & plasmalogen)

    10/01/2023 6:08:35 PM PDT · by ConservativeMind · 12 replies
    Medical Xpress / Engineering ^ | Sept. 28, 2023 | Wei Xiong et al
    A new review highlights the significant role of dietary lipids in preventing brain aging and cognitive decline. As the global burden of aging-related brain diseases, particularly dementia, continues to rise, this research offers promising insights into potential nutritional interventions that could improve brain function during aging. The review focuses on the intricate relationship between lipid homeostasis and brain aging, emphasizing the importance of maintaining synaptic plasticity to prevent cognitive impairment. By examining evidence from epidemiological and animal studies, the research team demonstrates the crucial functions of polyunsaturated fatty acids (PUFAs), specifically phospholipids such as phosphatidylcholine, phosphatidylserine, and plasmalogen, in promoting...