Free Republic

The widely used diabetes drug metformin changes blood metal levels in humans. The study is an important step in understanding the drug's many actions and designing better ones in the future. Metformin is the most widely prescribed diabetes drug in the world. Apart from lowering blood sugar levels, it is also known to have a broad range of beneficial side effects such as against tumors, inflammation and atherosclerosis. However, although it has been used for more than 60 years now, its mechanism of action is still not clear, hampering the development of even better drugs against these conditions. Ogawa Wataru...

WASHINGTON – The Federal Reserve on Wednesday approved a widely anticipated rate cut and signaled that two more are on the way before the end of the year as concerns intensified over the U.S. labor market even as inflation is still in the air. In an 11-to-1 vote signaling less dissent than Wall Street had anticipated, the Federal Open Market Committee lowered its benchmark overnight lending rate by a quarter percentage point. The decision puts the overnight funds rate in a range between 4.00%-4.25%. Newly installed Governor Stephen Miran was the only policymaker voting against the quarter-point move, instead advocating...

Beta blockers—drugs commonly prescribed for a range of cardiac conditions, including heart attacks—provide no clinical benefit for patients who have had an uncomplicated myocardial infarction with preserved heart function. Beta blockers have been the standard treatment for these patients for 40 years. This is a breakthrough discovery from the "REBOOT Trial." Additionally, a REBOOT substudy, shows that women treated with beta blockers had a higher risk of death, heart attack, or hospitalization for heart failure compared to women not receiving the drug. Men did not have this increased risk. Says Borja Ibáñez, MD.l, "Currently, more than 80% of patients with...

During Tuesday’s broadcast of Fox News Channel’s “Jesse Watters Primetime,” Sen. Josh Hawley (R-MO) discussed the connections of left-wing billionaire financier George Soros to the violent behavior exhibited by left-wing protesters. The Missouri Republican U.S. Senator described the Democratic Party as a “theater troupe” funded by Soros. “Senator, where do you suspect the money is going towards?” host Jesse Watters asked. Hawley replied, “Well, you can see what it’s going towards. It’s going towards these fake riots. It’s going towards all of the illegal immigration that we’ve been seeing. It’s going towards the Astroturf riots from Tesla dealerships to campuses...

Dozens of haredim protest outside Prison 10, block a van carrying detained draft dodgers, and manage to free one of them despite a heavy presence. Two soldiers lightly injured Dozens of haredim rioted Wednesday evening during a protest outside Prison 10, where detained haredi draft dodgers are being held. The protesters clashed with security forces in the area, blocking a van transporting approximately 20 haredi draft dodgers into the prison. Despite the presence of significant security personnel, the demonstrators succeeded in freeing one of the detainees from the vehicle. During the confrontation protesters hurled rocks and used tear gas. Two...

Kimmel LIED and claimed Charlie's killer was MAGA (doesn't make sense). Now he's finding out. ABC will take his stupid show off the air, after FCC head Brendan Carr trashed Kimmel for his lies and treathened ABC with consequences. FAFO.

Details have been released of the guest list, seating plan, drink and food for the state banquet being hosted by the King and Queen for Donald Trump and his wife Melania. A bespoke transatlantic whisky sour cocktail garnished with a toasted marshmallow set on a star-shaped biscuit "evoking the warmth of a fireside S'more" is being served at the lavish occasion. The guest list includes senior royals, stars of the world of golf, tech leaders and media mogul Rupert Murdoch, despite him and his his newspaper the Wall Street Journal being sued by the US president. There is also a...

The founder of Armed Queers SLC, a pro-gun LGBTQ group being investigated by the FBI for possible ties to accused Charlie Kirk sniper Tyler Robinson, has been identified as a radical transgender political organizer with ties to communist politics. Armed Queers SLC quietly scrubbed its online presence after Kirk was assassinated, but a law enforcement source told The Post that all open-source information on the group was downloaded and handed over to the FBI. The cache of information includes posts from Ermiya Fanaeian, the child of Iranian immigrants, according to the source familiar with the federal investigation, whose Instagram bio...

In a Daily Mail podcast, senior US news reporter Josh Boswell describes his investigation into Tyler Robinson's 'bizarre' internet activity, including his sexual interest in the 'furry' community. Boswell was the first investigative reporter to identify Robinson's roommate, 'trans gamer' Lance Twiggs, 22. Text messages reveal the two were in communication on September 10, the day right-wing influencer Charlie Kirk was killed. After identifying Twiggs using social media - who has not yet been charged with any crime in connection with the shooting - the investigative reporter was able to uncover various online accounts connected to Robinson.

The state’s largest teachers union came in for sharp criticism on Wednesday after it asked school districts to defend educators from bullying and harassment for speaking out on the death of the conservative activist Charlie Kirk. In a joint statement, Max Page and Deb McCarthy, the president and vice president of the Massachusetts Teachers Association, argued that the “ongoing campaign by extreme-right conservatives to discredit and defund public education has grotesquely exploited the shooting death of Charlie Kirk to launch attacks against people commenting on this public figure’s beliefs and statements.”

The New Logo Has Been Pulled and the Old Is Back The updated logo, which ditched the “Uncle Herschel” character and the words “Old Country Store,” has been tossed. The old one is back. “We have heard our guests, and we are continuing to listen. We are focused on the kitchen and our guests’ plates and serving up generous portions of craveable food with Cracker Barrel’s warm country hospitality,” a Cracker Barrel spokesperson said. The restaurant also tossed a plan to update restaurants, giving them a modern, sleek look. They have already remodeled four of 660. “You’ve shared your voices...

The nation’s service academies next month will announce they will accept scores from the Classic Learning Test, a standardized exam that emphasizes classical literature such as Greek and Roman classics and Christian thinkers beginning in the 2027 admissions cycle, according to internal communications obtained by POLITICO and a person familiar with the matter granted anonymity to discuss the policy change. The Pentagon’s move marks a victory for conservative lawmakers and activists who have pushed to elevate the test, known as the CLT, as an alternative to the SAT and ACT emphasizing “deep comprehension of classical texts.” According to the internal...

U.S. president kicked off his historic 2nd state visit to Britain at Windsor CastleWhile observers weren't necessarily expecting a bow or curtsy, they may not have predicted a greeting this informal, either. U.S. President Donald Trump's historic second state visit to Britain began Wednesday with a stop at Windsor Castle, where he was met by Prince William and Catherine, Princess of Wales. Trump stepped out of his helicopter, raised his hand in a salute and then shook William's hand. Then, upon greeting Catherine, Trump shook her hand and said, "You're beautiful. So beautiful." Catherine didn't appear to react one way...

Square profile picture Libs of TikTok @libsoftiktok Louisiana nurse Dustin Clark who’s also a drag queen was just arrested for allegedly abusing his infant adopted baby because the baby was being fussy. The baby ended up in the hospital with a fractured skull because of the abuse. He’s now facing 3 child abuse related charges.

A 75 minute podcast from Frank Turek who was a close friend of Charlie Kirk and an eyewitness to his assassination/martyrdom. https://www.youtube.com/watch?v=rVaxvKtw5NQ

Since 2016, George Soros’s Open Society Foundations (OSF), now run with his son Alexander, has poured over $80 million into groups tied to terrorism or extremist violence. The evidence is stark: Open Society has sent millions of dollars into U.S.-based organizations that engage in “direct actions” that the FBI defines as domestic terrorism. These groups include the Center for Third World Organizing and its militant partner Ruckus Society, which trained activists in property destruction and sabotage during the 2020 riots, and the Sunrise Movement, which endorsed the Antifa-linked Stop Cop City campaign, in which activists currently face over 40 domestic...

[Catholic Caucus] Cardinal Fernández claims synodality is not a ‘revision of doctrine and morality’Cdl. Victor Fernández lamented that ‘many priests have doubts, questions, disinterest, and rejection regarding the proposal of synodality.’The prefect of the Vatican’s doctrinal office has rejected the notion that synodality is “a matter of listening to everyone in order to carry out a democratic revision of doctrine and morality.”As prefect of the Dicastery for the Doctrine of the Faith, Cardinal Victor Manuel Fernández has been a key figure in the latter years of Pope Francis’ pontificate and thus the Synod on Synodality. The synod – arguably Francis’...

President Trump announced Wednesday that he will designate Antifa as a “MAJOR TERRORIST ORGANIZATION” and push for investigations of backers of the radical, left-wing group. “I am pleased to inform our many U.S.A. Patriots that I am designating ANTIFA, A SICK, DANGEROUS, RADICAL LEFT DISASTER, AS A MAJOR TERRORIST ORGANIZATION,” Trump wrote on Truth Social. “I will also be strongly recommending that those funding ANTIFA be thoroughly investigated in accordance with the highest legal standards and practices,” the president added. “Thank you for your attention to this matter!” …

… As the foregoing history suggests, the fundamental legal framework that governs the broadcast industry sets it apart from other media. In broadcasting, the Federal Government grants exclusive free speech rights to licensees, while denying such freedom to others. To justify this privileged treatment, Congress and the courts have mandated that licensees serve as “public trustees” of the airwaves. The public trustee model has given rise to a distinct genre of First Amendment jurisprudence. Unlike newspapers and magazines, broadcasters have affirmative statutory and regulatory obligations to serve the public in specific ways. Despite the philosophical complications and political tensions that...

A day after President Donald Trump endorsed the prospect of designating Antifa as a domestic terrorist organization, Washington State Republican Party Chair Jim Walsh says he is convinced, like the president, that many Antifa protesters are “paid agitators.” “We've seen examples of that sort of behavior here in Washington,” Walsh texted The Center Square on Tuesday. The movement has historical roots in the Pacific Northwest, including forming one of the nation's earliest modern such groups, Rose City Antifa, in Portland, Ore., in 2007. On Monday, The Center Square asked the president if he would designate Antifa a domestic terror organization...