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Researchers discover why taking a mushroom supplement slows or prevents prostate cancer from getting worse
Medical Xpress / City of Hope National Medical Center / Clinical and Translational Medicine ^ | Nov. 12, 2024 | Xiaoqiang Wang et al

Posted on 11/25/2024 8:25:44 PM PST by ConservativeMind

Researchers now understand why taking an investigational white button mushroom supplement shows promise in slowing and even preventing prostate cancer from spreading among men who joined a phase 2 clinical trial studying "food as medicine."

Looking at preclinical and preliminary human data, the scientists found that taking white button mushroom pills reduces a class of immune cells called myeloid-derived suppressor cells (MDSCs), which has been linked to cancer development and spread.

"City of Hope researchers are investigating foods like white button mushroom, grape seed extract, pomegranate, blueberries and ripe purple berries called Jamun for their potential medicinal properties. We're finding that plant-derived substances may one day be used to support traditional cancer treatment and prevention practices," said Shiuan Chen, Ph.D.

"This study suggests that 'food as medicine' treatments could eventually become normal, evidence-based cancer care that is recommended for everyone touched by cancer."

In mouse models, researchers found that administration of white button mushroom extract significantly delayed the growth of tumors and extended the survival of mice. It also improved T cell immune response through the reduction of MDSC levels in animal models, meaning it improved the immune system's ability to kill cancer.

The researchers profiled blood draws from some of the men participating in City of Hope's phase 2 clinical trial. The men were under active surveillance as they took white button mushroom supplements. Focusing on eight participants' samples before and after three months of white button mushroom treatment, the scientists found that there were less tumor-creating MDSCs and more anti-tumor T and natural killer cells, suggesting white button mushroom rebuilds anti-cancer immune defense and slows cancer growth.

(Excerpt) Read more at medicalxpress.com ...


TOPICS: Health/Medicine
KEYWORDS: blueberries; buttonmushrooms; cancer; foodasmedicine; grapeseed; grapeseedextract; jamun; mushroom; mushrooms; pomegranate; pomegranates; prostate; prostatecancer; whitebuttonmushrooms
Everyone can find white button mushrooms to eat.

It might even help with your prostate cancer.

1 posted on 11/25/2024 8:25:44 PM PST by ConservativeMind
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To: Mazey; ckilmer; goodnesswins; Jane Long; jy8z; ProtectOurFreedom; matthew fuller; telescope115; ...

The “Take Charge Of Your Health” Ping List

This high volume ping list is for health articles and studies which describe something you or your doctor, when informed, may be able to immediately implement for your benefit.

Email me to get on either the “Common/Top Issues” (20 - 25% fewer pings) or “Everything” list.

2 posted on 11/25/2024 8:26:16 PM PST by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind

bttt


3 posted on 11/25/2024 8:31:54 PM PST by linMcHlp
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To: ConservativeMind

Most likely not limited to just prostate cancer.


4 posted on 11/25/2024 8:31:55 PM PST by steve86 (Numquam accusatus, numquam ad curiam ibit, numquam ad carcerem™)
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To: ConservativeMind

Taste good cooked in butter.


5 posted on 11/25/2024 9:00:20 PM PST by IDFbunny (Crimea was never Ukraine.)
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To: ConservativeMind

Each day I have 0.5g each of Reishi and Turkey Tail, 1.0g of Lion’s Mane and Cordyceps, plus 70-80g of cooked white button mushrooms.


6 posted on 11/25/2024 9:09:41 PM PST by The Truth Will Make You Free ( )
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To: The Truth Will Make You Free

Grow your own?


7 posted on 11/25/2024 9:34:23 PM PST by BipolarBob (Our prodigal Haitian son has returned!! Prepare the fatted cat.)
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To: The Truth Will Make You Free

Has The addition of mushrooms to your diet made a noticeable difference in your health?


8 posted on 11/25/2024 9:35:22 PM PST by Michigan Bowhunter
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To: Michigan Bowhunter; BipolarBob
I get the powders online for about $40 a kilogram. I was already making a mix of a dozen other supplements so it wasn’t hard to add them in.

The shrooms are more of along term preventative thing so I can’t claim any direct noticeable difference. I knew Reishi is anti-cancer and Lion’s Mane is neurological and happened to read an article on other mushrooms.

To figure the dosages I mostly used the lower end of chatGPT recommendations.

I’ve always liked button mushrooms and get 24 ounces at Sam’s for 3.62 or sometimes mini portabellas for 4.42.

9 posted on 11/26/2024 12:21:13 AM PST by The Truth Will Make You Free ( )
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To: Michigan Bowhunter; BipolarBob
I should add that all mushrooms, especially shiitake, oyster, and maitake, are the richest source of ergothionine, which has longevity, antioxidant, anti inflammatory, neuroprotective, immune system support, and cellular health/DNA.

This is from a summary of chatGPT reply to “Benefits and sources of ergothionine.”

It’s kind of like dark chocolate, especially cacoa powder, is by far the highest source of theobromine (literally God-food) and pineapple (especially the core) is the only real source of bromelain.

10 posted on 11/26/2024 12:48:48 AM PST by The Truth Will Make You Free ( )
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To: The Truth Will Make You Free

I eat tons of mushrooms on everything!

Cool

B3 and B12 are the only supplements I use regularly


11 posted on 11/26/2024 1:41:19 AM PST by baclava
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To: baclava

Derp, D3


12 posted on 11/26/2024 1:42:27 AM PST by baclava
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To: ConservativeMind

At the suggestion of another pet owner in our neighborhood, when our dog was diagnosed with liver cancer, we purchased Wild Turkey Tail Mushroom Powder on amazon. We put a half tsp of the powder in her food every morning and night and she lived for 2 years past the initial diagnosis. The powder is supposed to stop the growth of abnormal cells - we don’t know if it worked but liver cancer is a pretty serious and fast acting disease. We were blessed with an additional 2 years with our beloved.


13 posted on 11/26/2024 2:55:52 AM PST by Cowgirl of Justice
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To: ConservativeMind

Additional info in an older article listed at the bottom of this story.

https://medicalxpress.com/news/2021-04-phase-trial-mushroom-tablets-prostate.html

I eat a lot of white and baby bellas, mostly sauteed in evoo with maybe a pinch of thyme, s&p. Its an inexpensive way to add low cal protein. Good to know there may be other benefits, too.


14 posted on 11/26/2024 3:08:54 AM PST by Adder (End fascism...defeat all Democrats.)
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To: ConservativeMind

I love mushrooms, especially the purple ones....................


15 posted on 11/26/2024 5:13:02 AM PST by Red Badger (Homeless veterans camp in the streets while illegals are put up in 5 Star hotels....................)
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To: The Truth Will Make You Free

I’ve tried many exotic and everyday mushrooms but the coriolus versicolor is best imho.

https://youtu.be/qqzXYGQbm6g

Heard about them from AndWeKnow.com podcasts - petclub247 link at AWK website


16 posted on 11/26/2024 5:34:34 AM PST by BrandtMichaels ( 1st Peter 4:8 "Above all, love each other deeply because love covers a multitude of sins." )
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To: ConservativeMind

Bookmark


17 posted on 11/26/2024 5:58:58 AM PST by fedupjohn (Waiting for Trump's new Caribbean Resort "Club Gitmo" to open for business! )
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To: Cowgirl of Justice

My friend’s greyhound got cancer in the leg.
Her other greyhound had gotten the same thing a few years ago, died from it after it spread.
Have a friend who is a dog whisperer who told me to have her get turkey tail mushroom for dogs.
She checked with the vet; he said it couldn’t hurt.
Six months later the cancer was gone


18 posted on 11/26/2024 9:03:36 AM PST by sweetiepiezer (WINNING is not getting old!!! ❤️USA❤️)
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To: ConservativeMind

—> “City of Hope researchers are investigating foods like white button mushroom, grape seed extract, pomegranate, blueberries and ripe purple berries called Jamun for their potential medicinal properties.

We’ve done this for decades.

—> We’re finding that plant-derived substances may one day be used to support traditional cancer treatment and prevention practices

Been happening for decades.

MDs not interested.


19 posted on 11/26/2024 7:55:09 PM PST by aMorePerfectUnion (🦅 MAGADONIAN ⚔️ LIFE )
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To: BrandtMichaels

The link was something about pet foods. A youTube search for coriolus versicolor brought up several videos about the common name “Turkey Tail.” Good stuff.


20 posted on 11/29/2024 1:10:21 PM PST by The Truth Will Make You Free ( )
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