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The wonder drug that could reverse the ageing process
uk.news.yahoo.com ^ | 3 April 2019 | Sarah Knapton

Posted on 04/03/2019 11:35:30 AM PDT by Red Badger

With its pudgy body, tired eyes and hair loss, the lower mouse could easily be the father of the sprightly and alert animal nestling alongside.

But they are actually the same age, the result of extraordinary trials of drugs which are slowing down or even reversing the ageing process.

Scientists now believe that ageing itself is responsible for many major conditions such as Alzheimer’s, Parkinson’s, arthritis, cancer, heart disease, and diabetes. And they think they have found a way to turn it off.

Anti-ageing drugs - dubbed ‘senolytics’ - are currently being trialled in humans and unlike previous tests which have focussed on a single disease, these drugs work like a broad-spectrum antibiotic, preventing or alleviating most age-related illnesses and frailty.

Scientists at The Mayo Clinic, who first coined the term senolytics, already have six trials in humans under way and plan to start six more shortly. If successful, they estimate that drugs to slow down ageing could be ready within two years.

In mice, the drugs extend lifespan by 36 per cent, the equivalent of adding around 30 years to humans, and crucially the animals remained in good health.

Clinical geriatrician Dr James Kirkland, Director of the Robert and Arlene Kogod Center on Aging at Mayo Clinic, said: “Most people don’t want to live to 130 and feel like they’re 130 but they wouldn’t mind living to 90 or 100 and feel like they’re 60. And now that can actually be achieved in animals.

“Ageing itself is the highest risk factor for most of the chronic diseases. And if you get one age-related disease, you’ve got a huge chance of having several.

“You tend to find older individuals who are completely healthy and are playing 18 rounds of golf a day, or they’ve got three,five or 10 different conditions.

(Excerpt) Read more at uk.news.yahoo.com ...


TOPICS: Business/Economy; Food; Health/Medicine; Pets/Animals
KEYWORDS: ageing; aging; alzheimers; antiaging; antiagingdrug; arthritis; cancer; diabetes; drjameskirkland; health; heartdisease; longevity; longevitydrug; mayoclinic; medications; parkinsons; senolytics; tgn; wonderdrug
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To: sauropod

bkmk


61 posted on 04/03/2019 1:47:43 PM PDT by sauropod (Yield to sin, and experience chastening and sorrow; yield to God, and experience joy and blessing.)
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To: CatOwner
Swell, so the Soros and Hillarys of the world lived into their 100s.

Hope the Lord comes before that cuz I want to see the both of them get dropped kicked into the Pit of Hell.

62 posted on 04/03/2019 1:51:21 PM PDT by Slyfox (Not my circus, not my monkeys)
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To: SkyDancer

No one gets out alive.


63 posted on 04/03/2019 2:02:43 PM PDT by Carriage Hill (A society grows great when old men plant trees, in whose shade they know they will never sit.)
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To: carriage_hill

Well then I guess dying is nature’s way of telling us to slow down?


64 posted on 04/03/2019 2:04:35 PM PDT by SkyDancer ( ~ Just Consider Me A Random Fact Generator ~ Eat Sleep Fly Repeat ~)
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To: carriage_hill

No one gets out alive.

https://www.youtube.com/watch?v=oOzpncIHCLs


65 posted on 04/03/2019 2:30:25 PM PDT by Disambiguator (Keepin' it analog.)
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To: SkyDancer

Mother Nature’s in charge; we’re just along for the ride. And a short one, it is.


66 posted on 04/03/2019 2:37:29 PM PDT by Carriage Hill (A society grows great when old men plant trees, in whose shade they know they will never sit.)
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To: NativeSon

It makes such a mess and it stains. If I remember right it also didn’t dissolve well but might be thinking of something else.


67 posted on 04/03/2019 2:38:33 PM PDT by RummyChick (I have no inside sources, media sources, or federal government employee sources. NONE)
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To: Disambiguator

Wow, I hadn’t heard that song in 35-40yrs; thanks for the trip down memory lane.


68 posted on 04/03/2019 2:43:10 PM PDT by Carriage Hill (A society grows great when old men plant trees, in whose shade they know they will never sit.)
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To: Red Badger

Did you read the Oath pop up that prefaces the article?


69 posted on 04/03/2019 3:03:02 PM PDT by Eagles6
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To: Red Badger

I read an interview with Keith about 20 years ago where he said Mic was obsessed with tennis, taking lessons and playing every day. He finally talked Keith into playing him. “I kicked his ass!”


70 posted on 04/03/2019 3:30:01 PM PDT by Hugin ("Not one step from his weapons should a traveler take"...Havamal 38)
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To: carriage_hill

It was the first thing I thought of when I saw your post.


71 posted on 04/03/2019 4:05:01 PM PDT by Disambiguator (Keepin' it analog.)
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To: Moonman62

I’d pass. Being married to someone for 50 years is one thing - but 150 years? that’s a challenge!


72 posted on 04/03/2019 4:33:26 PM PDT by blueplum ("...this moment is your moment: it belongs to you... " President Donald J. Trump, Jan 20, 2017)
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To: Sequoyah101

I do not think the State will allow you to go on living. Sarah Palin was right: Death Panels will be instituted.

Those slippery slopes are real: See Roe v. Wade and infanticide.


73 posted on 04/03/2019 5:06:29 PM PDT by YogicCowboy ("I am not entirely on anyone's side, because no one is entirely on mine." - J. R. R. Tolkien)
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To: Red Badger

I have a friend who died too young 101 years and 6 months


74 posted on 04/03/2019 5:50:05 PM PDT by Vendome (I've Gotta Be Me https://www.youtube.com/watch?v=BB0ndRzaz2o)
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To: RummyChick

I’ll look into it. I’m interested in doing some research on compounds to be used in combination to have desirable physio effects.


75 posted on 04/03/2019 7:35:15 PM PDT by NativeSon ( Grease the floor with Crisco when I dance the Disco)
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To: Quality_Not_Quantity

Reminds me of my last class reunion. Everyone sent their parents except me!


76 posted on 04/03/2019 8:04:12 PM PDT by John Milner (Marching for Peace is like breathing for food.)
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To: ckilmer

It’s what I do. And when you burn fat and not sugar, you have to work to keep from losing too much weight. It’s crazy.


77 posted on 04/03/2019 8:09:56 PM PDT by Yaelle
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To: Bonemaker

My first job was fueling aircraft at a busy municipal airport with a fancy restaurant, The Red Baron, at the top of the tower (making it a favorite leg on long flights).

A Texas oil millionaire used to fly in for lunch. He had a Turbo Centurian II with a custom N# and paint job: N101WT [101 Whiskey Tango = 101 Wild Turkey], with the Turkey logo on the tail and fin. Gorgeous plane with a three-blade prop.

It was obviously his favorite drink, although I assume he did not buy any at the Baron if he was going to fly more that day.


78 posted on 04/04/2019 12:50:25 AM PDT by YogicCowboy ("I am not entirely on anyone's side, because no one is entirely on mine." - J. R. R. Tolkien)
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To: RummyChick

Consider investigating, for starters:

Astragalus.
Jiaogulan.
Gotu Kola.
Ho Shou Wu.
Mucuna Pruriens.
Ashwaganda.
Holy Basil.
Cordyceps.
Moringa oleifera.
Hydrilla verticillata.
Ashitaba.

(I am not making any medical claims.)


79 posted on 04/04/2019 1:01:21 AM PDT by YogicCowboy ("I am not entirely on anyone's side, because no one is entirely on mine." - J. R. R. Tolkien)
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To: blueplum

I’d pass. Being married to someone for 50 years is one thing - but 150 years? that’s a challenge!

...

Didn’t Jesus say that there is no marriage in Heaven?


80 posted on 04/04/2019 1:06:14 AM PDT by Moonman62 (Facts are racist.)
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