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Keyword: virions

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  • The total number and mass of SARS-CoV-2 virions in an infected person (and in the entire world)

    12/10/2020 11:59:08 AM PST · by ProtectOurFreedom · 6 replies
    medRxiv ^ | November 17, 2020 | Ron Sender, Yinon M. Bar-On, Avi Flamholz, Shmuel Gleizer, Biana Bernsthein, Rob Phillips, Ron Milo
    Quantitatively describing the time course of the SARS-CoV-2 infection within an infected individual is important for understanding the current global pandemic and possible ways to combat it. Here we integrate the best current knowledge about the abundance of potential SARS-CoV-2 host cells and typical concentrations of virions in bodily fluids to estimate the total number and mass of SARS-CoV-2 virions in an infected person. We estimate that each infected person carries 109-1011 virions during peak infection, with a total mass of about 1 - 100 μg, which curiously implies that all SARS-CoV-2 virions currently in the world have a mass...