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The total number and mass of SARS-CoV-2 virions in an infected person (and in the entire world)
medRxiv ^ | November 17, 2020 | Ron Sender, Yinon M. Bar-On, Avi Flamholz, Shmuel Gleizer, Biana Bernsthein, Rob Phillips, Ron Milo

Posted on 12/10/2020 11:59:08 AM PST by ProtectOurFreedom

Quantitatively describing the time course of the SARS-CoV-2 infection within an infected individual is important for understanding the current global pandemic and possible ways to combat it. Here we integrate the best current knowledge about the abundance of potential SARS-CoV-2 host cells and typical concentrations of virions in bodily fluids to estimate the total number and mass of SARS-CoV-2 virions in an infected person.

We estimate that each infected person carries 109-1011 virions during peak infection, with a total mass of about 1 - 100 μg, which curiously implies that all SARS-CoV-2 virions currently in the world have a mass of only 0.1-1 kg.

Knowledge of the absolute number of virions in an infected individual can put into perspective parameters of the immune system response, minimal infectious doses and limits of detection in testing.

(Excerpt) Read more at medrxiv.org ...


TOPICS: Culture/Society; Miscellaneous; News/Current Events
KEYWORDS: covid19; mass; virions
After reading a number of articles on FR about the RT-PCR technology and how there is no isolated and concentrated sample of SARS-COV-2, I got wondering about how the scientists can determine if you have the virus if they don't have a reference sample of the virus itself.

That in turn got me to thinking about why the virus hasn't been concentrated which led, naturally, to wondering how much total COVID virus there is in the entire planet and how you could concentrate it.

I found a couple of amateur attempts to answer this question and those sleuths guesstimated maybe 1.5 grams in the entire world.

Then I found this paper by some scientists who think that the entire world has 100 g to 1,000 g of virus. But they are summing up the PEAK virion load at maximum infection time in every infected individual. Obviously not all infected individuals are at peak viral load simultaneously. If you assume that the average load in all currently-infected individuals is 20% of peak load (purely a guesstimate by me), you get 20 g to 200 g of virus circulating in the entire earth at any moment in time.

Think about that! Just 0.7 to 7 ounces of infectious material spread over the entire planet has brought us to our knees. That is astonishing.

1 posted on 12/10/2020 11:59:08 AM PST by ProtectOurFreedom
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To: ProtectOurFreedom

It is pretty remarkable, but remember, only 3 words will Chop our Legs off at the Knees!!

President Joe Biden


2 posted on 12/10/2020 12:03:43 PM PST by eyeamok
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To: ProtectOurFreedom

There must be bodies everywhere.


3 posted on 12/10/2020 12:04:26 PM PST by blueunicorn6 ("A crack shot and a good dancer”)
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To: ProtectOurFreedom

“After reading a number of articles on FR about the RT-PCR technology and how there is no isolated and concentrated sample of SARS-COV-2”

Why do people keep saying this and attribute importance to it?


4 posted on 12/10/2020 12:06:46 PM PST by ifinnegan (Democrats kill babies and harvest their organs to sell)
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To: ifinnegan

Doesn’t matter if it’s important or not. That is what triggered my question — “Just how much SARS-COV-2 virus is there in the world?”


5 posted on 12/10/2020 12:09:51 PM PST by ProtectOurFreedom ("Inside Every Progressive Is A Totalitarian Screaming To Get Out" -- David Horowitz)
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To: ProtectOurFreedom
Sars-Cov-2 was isolated by the end of Feburary. Inactive cultures are being used in research.
6 posted on 12/10/2020 1:13:04 PM PST by Widget Jr
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To: ProtectOurFreedom
So there are 10^18 to 10^20 virions, virus particles, of Covid in the world. If you threw them all in a giant lottery bin with just one tagged as a winner how would grabbing the winning one compare other longshot bets?

Well the biggest lottery winner in all time paid out $1.6 Billion. Presuming a $1 starting stake, to roughly match a COVID lottery winner you'd have square that. Ie. bet your $1 to win the initial lottery of $1.6B. Then bet that whole $1.6B on something that paid out 1.6B times on all of it. Rather hard to conceive and that just gets you to the low end of the range.

So try a more real world example. How would winning the COVID lottery compare with the odds of Joe Biden's comback 'wins' in MI, WI, PA and GA during the wee hours of 11/4 all being by honest chance? Well according to the stats expert cited in the Texas case you'd have to cube that. Bet your $1 stake and win a COVID lottery. Bet all those winnings again and win a second COVID lottery multiplier. Then bet all of that and win a third straight COVID lottery. That would roughly equal the 1 in a quadrillion (10^15) odds for each of those four comebacks and winning all four if your COVID lotteries paid out at the high end of that range. Aka one in Novemdecillion (10^60) odds. If they paid out at the low end of that range you'd still need a 1 in a million additional win to get there. But there is no evidence of fraud...

7 posted on 12/10/2020 7:15:06 PM PST by JohnBovenmyer (Dewey eyed Joe lost )
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