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The disease is not normally infectious, but people who received grafts from cadavers did show telltale markers in their brains For the second time in four months, researchers have reported autopsy results that suggest Alzheimer's disease might occasionally be transmitted to people during certain medical treatments--although scientists say that neither set of findings is conclusive. The latest autopsies, described in the Swiss Medical Weekly on January 26, were conducted on the brains of seven people who died of the rare, brain-wasting Creutzfeldt-Jakob disease (CJD). Decades before their deaths, the individuals had all received surgical grafts of dura mater--the membrane that...

Scientists are reporting that, for the first time, they have made an artificial prion, or misfolded protein, that can, by itself, produce a deadly infectious disease in mice and may help explain the roots of mad cow disease. The findings, being reported today in the journal Science, are strong evidence for the "protein-only hypothesis," the controversial idea that a protein, acting alone without the help of DNA or RNA, a cousin of DNA, can cause certain kinds of infectious diseases. The concept was introduced in 1982 by Dr. Stanley Prusiner, a neurology professor at the University of California, San Francisco,...