Stronger quadriceps muscles, relative to the hamstrings, may lower the risk of total knee replacement, according to research. Researchers said the findings could inform strength-training programs for people with advanced arthritis in the knee. "The two muscle groups act as counter forces, and the balance between them enables a wide range of activities while protecting the knee joint," said Upasana Upadhyay Bharadwaj, M.D. "An imbalance, in addition to other factors, leads to a change in the biomechanics resulting in the progression of osteoarthritis." Dr. Upadhyay Bharadwaj and colleagues evaluated thigh muscle volume in 134 participants from the Osteoarthritis Initiative. They...