In patients with chronic kidney disease, the loss of podocytes—part of the kidney's glomerular filtration barrier—causes irreversible disease progression. So far, physicians and researchers have found no way to effectively prevent podocyte damage, loss, and deterioration leading to end-stage kidney disease. Laura Perin, Ph.D. conducted a study that is offering promising results. They fed animal models with chronic kidney disease a specialized low-salt, fasting-mimicking diet (LS-FMD) equivalent to the recommended daily intake for human patients with chronic kidney disease. The researchers found that six cycles of this diet slowed the deterioration of kidney structures and function in rodents. Crucially, it...