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  • In Down syndrome mice, 40Hz light and sound improve cognition, neurogenesis and connectivity

    05/07/2025 9:59:37 PM PDT · by ConservativeMind · 39 replies
    In research, scientists found that 40Hz sensory stimulation improved cognition and circuit connectivity and encouraged the growth of new neurons in mice genetically engineered to model Down syndrome. The method, called GENUS (for Gamma Entrainment Using Sensory Stimulation), could provide clinical benefits. In the first set of experiments, the team shows that an hour a day of 40Hz light and sound exposure for three weeks was associated with significant improvements on three standard short-term memory tests—two involving distinguishing novelty from familiarity and one involving spatial navigation. Because these kinds of memory tasks involve a brain region called the hippocampus, the...
  • Fasting linked to 20% survival boost in colorectal cancer patients

    04/13/2025 10:57:15 AM PDT · by ConservativeMind · 13 replies
    Medical Xpress / BGI Genomics / PLOS ONE ^ | April 9, 2025 | Ori Tal et al
    Fasting has shown its potential to reduce colorectal cancer risk by triggering cellular changes that may slow tumor growth, with a study demonstrating a 20% improvement in overall survival. However, lifestyle changes alone aren't enough for prevention. Fasting has been shown to activate autophagy, the body's natural process of cleaning out damaged cells and regenerating healthy ones. According to a review, autophagy plays a key role in preventing cancer development by maintaining cellular health and reducing oxidative stress. By clearing away cells that might otherwise turn cancerous, fasting may help the body maintain a more stable and resilient internal environment....
  • Fasting diet may aid kidney function, study suggests

    11/09/2024 8:37:19 PM PST · by ConservativeMind · 9 replies
    In patients with chronic kidney disease, the loss of podocytes—part of the kidney's glomerular filtration barrier—causes irreversible disease progression. So far, physicians and researchers have found no way to effectively prevent podocyte damage, loss, and deterioration leading to end-stage kidney disease. Laura Perin, Ph.D. conducted a study that is offering promising results. They fed animal models with chronic kidney disease a specialized low-salt, fasting-mimicking diet (LS-FMD) equivalent to the recommended daily intake for human patients with chronic kidney disease. The researchers found that six cycles of this diet slowed the deterioration of kidney structures and function in rodents. Crucially, it...