In Down syndrome mice, 40Hz light and sound improve cognition, neurogenesis and connectivity

In research, scientists found that 40Hz sensory stimulation improved cognition and circuit connectivity and encouraged the growth of new neurons in mice genetically engineered to model Down syndrome.

The method, called GENUS (for Gamma Entrainment Using Sensory Stimulation), could provide clinical benefits.

In the first set of experiments, the team shows that an hour a day of 40Hz light and sound exposure for three weeks was associated with significant improvements on three standard short-term memory tests—two involving distinguishing novelty from familiarity and one involving spatial navigation.

Because these kinds of memory tasks involve a brain region called the hippocampus, the researchers looked at neural activity there and measured a significant increase in activity indicators among mice that received the GENUS stimulation.

The researchers found that in the dentate gyrus, stimulated mice had significantly more synapses.

The team not only examined gene expression across individual cells, but also analyzed that data to assess whether there were patterns of coordination across multiple genes. Some of this evidence further substantiated the idea that 40Hz-stimulated mice made important improvements in synaptic connectivity, but another key finding highlighted a role for TCF4, a key regulator of gene transcription needed for generating new neurons, or "neurogenesis."

The team's analysis of genetic data suggested that TCF4 is underexpressed in Down syndrome mice but the researchers saw improved TCF4 expression in GENUS-stimulated mice.

The analysis of gene expression modules also yielded other key insights. One is that a cluster of genes whose expression typically declines with normal aging and in Alzheimer's disease, remained at higher expression levels among mice who received 40Hz sensory stimulation.

And the researchers also found evidence that mice that received stimulation retained more cells in the hippocampus that express Reelin. Reelin-expressing neurons are especially vulnerable in Alzheimer's disease.

Finally, people are beginning to recognize what I have been saying for several decades, “It’s all about frequencies of consciousness.” It’s what all religions are teaching us to do. This is where medical science begins to understand why religion(s) teach what they do.

Frequency, in Hertz refers to the number of wave cycles per second. Our reason for experiencing life on earth is to raise our frequency of consciousness to a level where we can perceive directly with consciousness, rather than our physical body sensory receptors and neurons.

In the physical body, our firing rate of our neurons or action potential firing rate which is measured by an EEG represents our frequency of consciousness. Think of spark plug wires on a car. In order for the car engine to reach higher RPM’s (Revolutions per Minute is just another measure of frequency), the sparks must be more frequent traveling through the spark plug wire to ignite the gas more times per minute. So it is with our neurons when consciousness grows to higher frequencies.

I’ve been studying Transcranial Magnetic Stimulation (TMS), a noninvasive treatment that uses magnetic fields to stimulate nerve cells in the brain for many years as the head of our psychiatry department specialized in this research at the med school. It’s a procedure where various frequency magnet fields are projected onto the brain through a helmet primarily to help alleviate symptoms of major depression and other mental health conditions. It is often used when other treatments, like medications and therapy, have not been effective. I could not share what I see as the researchers are no ready for it. They are actually overriding the connection between the soul and the brain. This is why the process only provides temporary relief as the root cause of the physical symptoms is in the person’s soul, not heir brain. The brain is a receiver and transmitter more that a processor or computer.

Ever since I died in 1988 and returned to my body, my consciousness frequency has been super high, to the point where my perception of reality includes consciousness itself as a physical object. It’s how I read the stored memories in people’s souls. Thus, I perceive the connection between the stored memory or perceptual programming even in a person’s soul and their physical body.

Our souls grow to higher frequencies of consciousness as we experience life. There are four basic frequencies of consciousness that correspond to the levels of development while limited to the physical body perception. While they progress in sequence through stages of development and correlate with age, the rates of developmental progression vary for each soul. These four stages are Delta, Theta, Alpha, and Beta. These are the stages for consciousness “in the physical body.”

The prefrontal cortex in the brain which is responsible for analytical thought processing does not fully develop until about age twenty-five. For some people it never develops.

The light therapy mentioned in this article is just one technique of using an external stimulus to increase the frequency of consciousness in a person. There are many such types of stimulations.

40 Hz light refers to sensory stimulation that flickers at a frequency of 40 hertz, which has been studied for its potential benefits in treating Alzheimer’s disease. Research suggests that this light stimulation may improve cognitive functions and reduce harmful proteins associated with Alzheimer’s in both animal models and early human studies. (It increases the consciousness frequency as an external stimulation.)

Consciousness flows through a person’s soul. It has many of the same characteristics as electricity, the energy which is recognized as flowing through our neurons in our physical bodies. Just as electricity must have an inflow and an outflow, so must consciousness in order for it to flow and perform work.

Masculine consciousness is the inflow and feminine consciousness is the outflow. Both are equally important as like a light bulb, unless both wires are connected (inflow and outflow) the bulb will not light. So it is with people’s brains when they try to think.

The attraction between souls in relationships is due to a pairing of inflows and outflows of consciousness in our souls. While all souls have both, we tend to develop one aspect of consciousness, masculine or feminine as dominant that corresponds to our gender.

Right now, souls on earth are growing faster than ever and people are experiencing both aspects of consciousness as they shift back and forth between dominant aspects as their soul grows. This is the reason for the increase in gender identity issues on earth right now as souls are growing very fast. This is also the reason for the civil rights movement, the equal rights movement, and the resulting divorce rates as souls grow at various rates and their partner may no long resonate at the same frequency as they do, thus they search for a new compliment to their soul frequency. Gender identity is merely a function of the dominant aspect of consciousness at that tie, regardless of actual gender. This is not theory. It is what I directly observe in working with many gays and lesbians over the past thirty years. I do not judge, but merely help people to better understand themselves, a prerequisite to their self empowerment.

Just as electricity has resistance to its flow, sin causes a resistance to the flow of consciousness by creating an obstacle to Love in a person’s soul consciousness. I define sin as any obstacle to Love in a person’s soul. Love is critically important as it is the energy that binds the two aspects of consciousness together, thus stabilizing it so that it can grow to higher frequencies.

Without Love, the glue that holds the soul together, the soul cannot grow to the higher frequencies. Love is the most important ingredient in the soul growth process.

The ultimate goal for life on earth is “transcendence.’ This is where the soul frequencies grow above the 40 Hz rate and begin to perceive directly with consciousness. Medical science did not recognize these higher frequencies until the early 1960’s when EEG equipment began to switch to the old tube analog machines to digital. They then discovered what is referred to as the “Gamma Frequencies of Consciousness.”

Medical science is still very much in its infancy with research in this area. The definition of Gamma Frequency of consciousness varies in medical texts, some recognizing it as up to 100Hz. I laugh as there is no upper limit. In meditation, my consciousness has jammed FM receivers that operate in the Mega Hz. I discovered this in a conference hall when I was the only person in the big auditorium, meditating at 3 am and the sound system began creating backfeed like someone shoved a microphone into a speaker. It startled me, so I stopped meditating. The backfeed stopped. With further investigation, I found that someone had left the FM receivers for the lavalier microphones on and my consciousness was stimulating them from over a hundred feet away. I found that my own frequency of consciousness in meditation would change the sound coming through the PA system as I changed my own frequency of consciousness.

When Jesus taught us to Love God, He was telling us to raise our consciousness to the highest level possible at all times.

I’m using the above referenced article as a stepping stone to help people understand this topic, i.e. Frequencies of Consciousness. The ultimate goal in raising our consciousness frequency is to set us free of being shackled the these physical bodies.

As we raise our consciousness frequency, our soul expands far beyond our physical bodies. “Communion” is the act of merging our consciousness frequency with Jesus. It’s the reason He states that “I am in you and you are in Me” in John 14. As you raise your consciousness frequency you will actually see, feel, and experience this process rather than being limited to the theory. When our perception of reality shifts from being a physical body to being an expanded soul, we realize that we are “One with Everything.” Everything, including the entire earth, exists within us.

I pray that this makes sense. If it doesn’t, stop and pray or meditate on what you read. Prayer and meditation are excellent tools to raise the frequency of your consciousness.

Blessings on you journey through wholeness and transcendence.

OK Heavy Slide from the posted subject. T.D. You can develop calcium or fluoride deposits on your pineal gland, which is responsible for the major portion of melatonin production in your body. There is a lot of fluoride in tea IIRC?

https://ehjournal.biomedcentral.com/articles/10.1186/s12940-021-00700-7

"Fluoride from dietary and environmental sources may concentrate in calcium-containing regions of the body such as the pineal gland. The pineal gland synthesizes melatonin, a hormone that regulates the sleep-wake cycle. We examined associations between fluoride exposure and sleep outcomes among older adolescents and adults in Canada." snip

Results

Median (IQR) UFSG concentration was 0.67 (0.63) mg/L. Median (IQR) water fluoride concentration was 0.58 (0.27) mg/L among participants living in communities supplied with fluoridated municipal water and 0.01 (0.06) mg/L among those living in non-fluoridated communities. A 0.5 mg/L higher water fluoride level was associated with 34% higher relative risk of reporting sleeping less than the recommended duration for age [unweighted: RRR = 1.34, 95% CI: 1.03, 1.73; p = .026]; the relative risk was higher, though less precise, using survey-weighted data [RRR = 1.96, 95% CI: 0.99, 3.87; p = .05]. UFSG was not significantly associated with sleep duration. Water fluoride and UFSG concentration were not significantly associated with frequency of sleep problems or daytime sleepiness. Conclusions

Fluoride exposure may contribute to sleeping less than the recommended duration among older adolescents and adults in Canada."

As people lay awake at night wondering why they can't get to sleep they should be grateful for the fluoride that Government mandates for their water supply because they are concerned about protecting your teeth. As always, more grants and more study will be needed to fully understand this subject and provide cash to universities and professors.

C.M. Sorry for the slide. Thanks for your post!

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