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DNA usually forms the classic double helix shape of two strands wound around each other. While DNA can form some more exotic shapes in test tubes, few are seen in real living cells. However, four-stranded DNA, known as G-quadruplex, has recently been seen forming naturally in human cells. Now, in new research published today in Nature Communications, a team led by Imperial College London scientists have created new probes that can see how G-quadruplexes are interacting with other molecules inside living cells. G-quadruplexes are found in higher concentrations in cancer cells, so are thought to play a role in the...

With the successful arrest, prosecution and sentencing of Joseph DeAngelo, Sacramento District Attorney Anne Marie Schubert wanted to provide a voice to all those affected by the East Area Rapist. Several months ago, she invited those who lived in the Sacramento region during the 1970’s to email their stories to the DA’s Office. The response was overwhelming. Hundreds of individuals responded, recounting their experience and memories during that terrifying time. These stories have been put into an online book to share with the entire Sacramento community. This book is dedicated to all of the direct survivors and victims of the...

A source close to the investigation said Warner had bought “chemical precursors and security alarms” using a credit card in his name. The Sun was told: “The FBI has received information from a bank holding company on an active credit card for Warner. “Preliminary searches indicates the purchases of chemical precursors to make explosives and security alarms.” The source added: “Initial results also show nitroglycerin was found on a residue swab taken from a tree trunk at the blast site.” The source said: “It is believed Warner had his dog with him at the time of detonation. “Canine DNA has...

If we are creating antibodies to mRNA we are creating antibodies to our own proteins. And if we are creating antibodies to the mRNA nucleotides (the prongs) then we are creating an antibody to the corresponding segment of the DNA pair.If so we are creating antibodies AGAINST OUR OWN DNA!!!Now normally antibodies do not enter the cell so it may not be that bad, but Red Blood Cells extrude their nucleus in the bone marrow and if there is an antibody response (and thus inflammatory response, in the bone marrow it could severely damage the bone marrow (Normally macrophages just...

With new ‘elegant chemo,’ Israeli scientists edit genome to destroy cancer DNATel Aviv University team uses ‘microscopic scissors’ to pinpoint and eliminate cancerous cells; results of animal tests just published, trial in humans expected within 2 years Illustrative: Cancer cells inside the body (wildpixel; iStock by Getty Images)Israeli scientists say they have destroyed cancerous cells in mice with a method so pinpointed it’s as if “tiny scissors” were being used to target only affected cells, while leaving everything around them intact. “This is the first study in the world to prove that the CRISPR genome editing system, which works by...

Was Christopher Columbus born in Genoa, Italy? Most definitely not, say an unlikely collection of experts from European royalty, DNA science, university scholars, even Columbus's own living family. This ground breaking documentary follows a trail of proof to show he might have been much more than we know.Who Was The Real Christopher Columbus? | Secrets and Lies of Christopher Columbus | Timeline

Damage to the retina is the leading cause of blindness in humans, affecting millions of people around the world. Unfortunately, the retina is one of the few tissues we humans can't grow back. Unlike us, other animals such as zebrafish are able to regenerate this tissue that's so crucial to our power of sight. We share 70 percent of our genes with these tiny little zebrafish, and scientists have just discovered some of the shared genes include the ones that grant zebrafish the ability to grow back their retinas. "Regeneration seems to be the default status, and the loss of...

A series of 'death pits' containing 300 bodies have been discovered in Russia. The grisly site, which was found in the city of Yaroslavl, northeast of Moscow, likely dates back to the Mongol invasion of Europe in 1238. During this time, Genghis Khan's grandson, Batu Khan, decimated entire communities in his brutal - and bloodthirsty - bid for power. Now, thanks to scientific advances, DNA evidence has revealed that three of the victims were related and killed together: a grandmother, a mother and a grandson.

Hundreds of millions of Asian men alive today could be descendents of just 11 dynastic leaders who lived up to 4,000 years ago, according to researchers at the University of Leicester in the UK. The study, published in the European Journal of Human Genetics, looked at the Y-chromosome - the chromosome passed from father to son - in around 5,300 Asian men from more than a hundred different ethnic groups and nationalities. Most Y-chromosome types are extremely rare and so the prevalence of common Y-chromosome types amongst those they found in the Asian men they tested suggests hundreds of millions...

Genghis Khan, law giver, free trader and diplomat, is back with a new image By Richard Spencer in Ulan Bator (Filed: 11/07/2006) The Mongolian capital has been swamped with images of its former potentate, Genghis Khan, in honour of the anniversary of his unification of the nation in 1206. At the climax of celebrations in Ulan Bator yesterday, soldiers in traditional uniform and bearing yaks' tail standards heralded the unveiling of an enormous statue of the Great Khan in the main Sukhbaatar Square. The monument in which it is set contains earth and stones from the holy and historic places...

TOKYO (AP) - Archaeologists have unearthed the site of Genghis Khan's palace and believe the long-sought grave of the 13th century Mongolian warrior is somewhere nearby, the head of the excavation team said Wednesday. A Japanese and Mongolian research team found the complex on a grassy steppe 150 miles east of the Mongolian capital of Ulan Bator, said Shinpei Kato, professor emeritus at Tokyo's Kokugakuin University. Genghis Khan (c. 1162-1227) united warring tribes to become leader of the Mongols in 1206. After his death, his descendants expanded his empire until it stretched from China to Hungary. Genghis Khan built the...

Ghengis Khan a Prolific Lover, DNA Data Implies  Hillary Mayell for National Geographic News February 14, 2003   Genghis Khan, the fearsome Mongolian warrior of the 13th century, may have done more than rule the largest empire in the world; according to a recently published genetic study, he may have helped populate it too. An international group of geneticists studying Y-chromosome data have found that nearly 8 percent of the men living in the region of the former Mongol empire carry y-chromosomes that are nearly identical. That translates to 0.5 percent of the male population in the world, or...

Genetic markers for the Clan MacDougall... descends from Dougall, King of the Isle of Man and founder of the ancient Scottish Kingdom of the Isles and Lorn. Dougall (c1140-c1207) was the eldest son of Somerled, the ancient warrior sea-king and progenitor of the MacDonald, MacAllister, and MacDougall clans. Somerled expelled his Scoto-Norse rivals from Argyll, Kintyre and the Isles but was himself a Norseman paternally, having a genetic signature that is more common in Scandinavia than in Scotland. The first genetic signature for Somerled was discovered and published in 2005 by researchers at the University of Oxford, and since then,...

A growing number of ancient DNA studies on Neanderthals, Denisovans and Homo sapiens suggest intertwined evolutionary and population histories, including several admixture events between early modern and archaic humans. However, ancient nuclear and mtDNA sequences revealed phylogenetic discrepancies between the three groups that are hard to explain. For example, autosomal genomes show that Neanderthals and Denisovans are sister groups that split from modern humans more than 550,000 years ago. However, all but the earliest Neanderthal mtDNA samples are far more similar to those of modern humans than to those from Denisovans. These studies suggest that Neanderthals originally carried a Denisovan-like...

ROCHESTER, N.Y. (WHEC) — Rochester Police have made an arrest in a 35-year-old cold case murder investigation in Rochester. Police arrested Timothy Williams, 56, on Sept. 9 in the case of 14-year-old Wendy Jerome. The Rochester native, who was living in Melbourne, Florida at the time of his arrest, has been charged with her rape and murder. He was arraigned Friday morning and will be extradited to New York. According to police, on Nov. 22, 1984, Jerome had been raped about a quarter-mile from her own house. Her body was found in an alcove at School 33 on Webster Avenue....

Genealogy websites have become increasingly popular in recent years. These platforms are able to scour the web in search of documents and archival data, which can help users build historically accurate family trees. There’s also another side to genealogy websites that has attracted attention from privacy advocates: DNA testing. Websites like Ancestry.com can use DNA testing to find matches, but the fact that these platforms store this information on their end means that hackers could try and steal it. Tap or click here to see how Ancestry.com suffered a huge data breach. Since genealogy websites collect so much data, their...

[Ghost] DNA from an unknown ancient ancestor of humans that once bred with Denisovans still exists among the genomes of people today, a study has revealed. The different branches of the human family tree have interbred and swapped genes -- a processes known as 'introgression' -- on numerous occasions... Experts from the US found that some three per cent of the Neanderthal genome came from interbreeding with another ancient human group 300,000 years ago... The researchers used the algorithm to look at genomes from two Neanderthals, a Denisovan and two African humans. Alongside finding that a small proportion of the...

Authorities did not provide details on Neal’s illness, but said he was not exhibiting COVID-19 symptoms. Before his hospitalization, he was being held at the Theo Lacey maximum-security jail in Orange. In February 2019, Neal was identified as a suspect in the sex assault and killing of 11-year-old Linda Ann O’Keefe, a case that had stymied investigators for more than four decades. O’Keefe was abducted while walking home from school in the summer of 1973. Her strangled body was later found dumped in a ditch in Newport Beach’s Back Bay. DNA evidence collected at the crime scene eventually linked Neal...

SAN DIEGO — The average American lives to be around 75 or 80 years old; but if you had an opportunity to slow down the aging process and live an extra couple of decades would you take it? It’s a loaded question, strife with philosophical, religious, and societal considerations. Humans have pondered the possibilities of extended, or even immortal, life for as long as we’ve inhabited this planet. But at the end of the day it’s all just a daydream, right? Not necessarily, according to new research out of the University of California, San Diego. The study, led by UCSD...

NIH Researchers Have Generated the First Complete X Chromosome Sequence...The results, published today (July 14, 2020) in the journal Nature, show that generating a precise, base-by-base sequence of a human chromosome is now possible, and will enable researchers to produce a complete sequence of the human genome.