A DNA cutting tool that can manipulate human genomic DNA could ultimately find applications in gene therapy, say Japanese scientists.Makoto Komiyama, Narumi Shigi and colleagues at the University of Tokyo recently made the DNA cutter - ARCUT - and used it to cut bacterial DNA at one target site. Now they have shown that it can be tuned to cut human genomic DNA selectively and also to repair it."ARCUT's selectivity meant that the Tokyo team was able to use the cutter to target one site in human genomic DNA" ARCUT consists of a cerium(IV) complex which cuts the DNA and...