Free Republic

First-line treatment with the triplet combination of encorafenib, cetuximab and mFOLFOX6 significantly improved survival compared to the standard of care in patients with BRAF V600E-mutated metastatic colorectal cancer, according to data from the Phase III BREAKWATER trial. The findings demonstrated significantly longer progression-free survival (PFS) and overall survival (OS) compared to standard chemotherapy-based regimens. The median PFS was 12.8 months with the triplet combination compared to 7.1 months in the standard-of-care group, and the median OS was 30.3 months compared with 15.1 months, respectively. "The latest data from the BREAKWATER trial further confirms that targeting the BRAF V600E mutation up...

Ocasio-Cortez Calls for Trump to Be Impeached over U.S Strikes on Iran Rep. Alexandria Ocasio-Cortez (D-NY) speaks at a town hall gathering on May 2, 2025 in NewDavid Dee Delgado/Getty Images Elizabeth Weibel21 Jun 20258 Rep. Alexandria Ocasio-Cortez (D-NY) called for President Donald Trump to be impeached over the United States launching strikes on several nuclear sites in Iran. In a post on X, Ocasio-Cortez claimed that Trump’s decision to “bomb Iran without authorization” was a “grave violation” of the U.S. Constitution. “The President’s disastrous decision to bomb Iran without authorization is a grave violation of the Constitution and Congressional...

You knew this was coming. Cristina Laila reported: President Trump on Saturday evening announced the US dropped bombs on three nuclear sites in Iran. “We have completed our very successful attack on the three Nuclear sites in Iran, including Fordow, Natanz, and Esfahan. All planes are now outside of Iran air space. A full payload of BOMBS was dropped on the primary site, Fordow. All planes are safely on their way home. Congratulations to our great American Warriors. There is not another military in the World that could have done this. NOW IS THE TIME FOR PEACE! Thank you for...

Tony Conigliaro, the Major League Baseball player, was born on Sunday, January 7, 1945, in Revere, Massachusetts. Conigliaro was 19 years old when he broke into the major leagues on April 16, 1964, with the Boston Red Sox.

I know this has been a very busy night with the events in Iran, but this is something I've that's been on my mind for quite some time and I didn't know who else to ask. Basically, does anyone know of any good Christian chat sites? I know of the one at Rapture Forums, but I'd like to find others if possible. I know there are many Christians here on FR, and your fellowship and prayers have been a great comfort. But with me being home bound due to the hits my health has taken due to Covid/Long Covid, I'm...

Vince Vance and the Valiants

House Democrat Leader Hakeem Jeffries (D-NY) on Saturday night said that President Donald Trump has “failed” to bring peace to the Middle East after Trump ordered the bombing of Iranian nuclear sites. Jeffries, the leader of House Democrats, said in a written statement: Donald Trump promised to bring peace to the Middle East. He has failed to deliver on that promise. The risk of war has now dramatically increased, and I pray for the safety of our troops in the region who have been put in harm’s way. President Trump misled the country about his intentions, failed to seek congressional...

Jim Himes, the top Democrat on the House Intelligence Committee, was not briefed before the US strikes on Iran — even though his GOP counterpart on the panel, Chairman Rick Crawford, was in contact with the White House, per a person familiar. Sen. Mark Warner, the ranking Democrat on the Senate Intelligence Committee, also was not briefed before the attack, per a source familiar, but the GOP chairman, Tom Cotton, was briefed. Both Democrats are in the “Gang of Eight,” which typically would be briefed before a significant US military engagement. The Gang of Eight includes the House and Senate...

Israeli Prime Minister Netanyahu’s English statement after US strikes in Iran.

Seeing that Democrats are out-of-sync with what most voters want for the country, some of them are turning toward a strategy aimed at maximizing the number of sympathy votes they can get by instigating confrontations that result in them clashing with law-enforcement. Sen. Alex Padilla (Calif) made his pitch for "most oppressed" by describing how he was treated at the press conference of Secretary of Homeland Security Kristi Noem in Los Angeles. "I had serious questions that I wanted answered," Padilla said. "Why was Los Angeles singled out for ICE raids? Why did Trump illegally seize control over the California...

Join with fellow FREEPERS to pray for AMERICA: For those in Authority in Government, Family, Military, Business, Healthcare, Education, Churches, and the Media. I urge, then, first of all, that requests, prayers, intercession and thanksgiving be made for everyone: for kings and all those in authority that we may live peaceful and quiet lives in all godliness and holiness. ~ 1 Timothy 2:1-2 Religion Forum Threads labeled [Prayer] are closed to debate of any kind.

Any use of nuclear weapons likely will result in immediate global escalation.Israel has lost the initiative. Clearly losing the war. Large numbers of Israelis have fled or are fleeing Israel. “The tribe” is migrating.United States is staking all of our might on defending what amounts to maybe a couple million core Israelis. A country dependent on massive American support while we bleed.More than two million Arabs live in tiny Israel amid a total of only about 9 million people.Iran’s allies are powerful, proximate, and easily resupply Iran. Such as China using the new rail system:The global center of mass —...

Sen. John Fetterman (D-PA) responded to the news that the United States had carried out strikes on several nuclear sites in Iran, describing it as the “correct move.” In a post on X, Fetterman described Iran as being “the world’s leading sponsor of terrorism,” adding that they “cannot have nuclear capabilities.” Fetterman’s post came after President Donald Trump revealed in a post on Truth Social that the U.S. had completed a “very successful attack” on several nuclear sites in Iran. “As I’ve long maintained, this was the correct move by @POTUS,” Fetterman wrote. “Iran is the world’s leading sponsor of...

VIDEOWatch the exact moment that Steve Lookner of Agenda Free TV went from casually calm bordering on ennui to over the top EXCITED when he found out the news from the President that the USA dropped the Big Bombs on the Iranian nuke sites.

After the first “No Kings” protests fell flat and failed to gain traction, organizers are doubling down with plans for a second demonstration. The protests are scheduled for July 4th, as anti-ICE activists once again aim to disrupt America’s Independence Day celebrations and advance their agenda. According to a Facebook post, the second No Kings protest promises to deliver “No Kings” and “reclaim” freedom for the nation. The first demonstrations occurred earlier this month during President Donald Trump’s 250th celebration of the U.S. Army. Still, the far-left organizers failed to seize control or remove the president from office, so now...

This is an HISTORIC MOMENT FOR THE UNITED STATES OF AMERICA, ISRAEL, AND THE WORLD. IRAN MUST NOW AGREE TO END THIS WAR. THANK YOU!

@RepThomasMassie This is not Constitutional.

Clip from live concert shot at Les Arenes, Nimes, France and Feijenoord Stadium, Rotterdam - May 1992

In a bold show of force, U.S. jets flattened Iran's key nuclear sites overnight — delivering a crippling blow to Tehran's atomic ambitions and sending a clear message: the West will not tolerate nuclear terror. In a stunning and historic move, U.S. President Donald J. Trump confirmed early Sunday morning that American forces carried out a large-scale airstrike targeting three of Iran's most guarded nuclear facilities: Fordow, Natanz, and Esfahan. The operation, described by senior Israeli intelligence officials as "a strategic masterstroke," comes after weeks of escalating tension between Iran and Israel, during which Tehran launched multiple missile barrages into...