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Research reveals a major treatment advance for adults with newly diagnosed B lineage acute lymphoblastic leukemia (ALL). The randomized study evaluated blinatumomab immunotherapy in patients with a good prognosis after an initial round of chemotherapy. After about 3.5 years of follow-up, 83% of the patients who went on to receive additional standard consolidation chemotherapy plus experimental blinatumomab were alive versus 65% of those who received chemotherapy only. Current treatments for newly-diagnosed ALL frequently lead to remission. Still, unfortunately, relapses often occur in patients, leading to poor survival rates even in those with no measurable residual disease (MRD) after induction chemotherapy....

California scientists announced a breakthrough that could commercialize nuclear fusion in a few decades, but a Vancouver-based company has a method that claims to power homes with the technology by the early 2030s. Unlike at Lawrence Livermore National Laboratory, which used lasers to achieve net gain energy, General Fusion compresses hydrogen plasma inside a large cylinder to increase density and temperature. General Fusion's method uses high-powered pistons to squeeze liquid metal around the plasma to build pressure until the mixture hits 180 million degrees Fahrenheit - and fusion occurs. The firm says it plans to have its first commercial power...

Black women with symptoms of depression more often report sleep disturbances, self-criticism, and irritability than stereotypical symptoms such as depressed mood, according to a new study. "Based on our findings, it's possible that health care providers may miss depression symptoms in Black women, resulting in underdiagnosis and undertreatment," said Nicole Perez, Ph.D., RN. Depression is diagnosed based on symptoms that patients report during an evaluation by a health provider. Common symptoms include low mood, loss of interest in activities, changes in appetite or sleep, and feelings of hopelessness or worthlessness. But symptoms of depression can vary from one person to...

[Catholic Caucus] Omaha archdiocese walks back controversial gender policy for schoolsNEW YORK – Walking back a controversial six-page gender policy it planned to add to the archdiocesan school’s handbook on January 1, 2023, the Archdiocese of Omaha has replaced it with a narrower single-page policy that will be implemented for the 2023-2024 school year.The move comes after the former policy, which the archdiocese said was “prematurely shared” in August, generated pushback. Unlike the former, the revised policy doesn’t mention possible dismissal or disciplinary action for transgender students, and drops the portion that applied to school employees and volunteers.Archbishop George Lucas...

Having been arrested the previous day in the Bahamas, the star of the show, Sam Bankman-Fried, was unable to attend Tuesday’s House Financial Services Committee hearing on the stunning collapse of FTX. But as they say, the show, presided over by the petulant and uber entitled committee chair, Rep. Maxine Waters, went on. The congresswoman from California has grown accustomed to having her own way in the Democratic-controlled Congress and was clearly not pleased when Texas Rep. Lance Gooden, a Republican, challenged her authority. Waters tried to end the hearing before Gooden was allowed to question the witness, current FTX...

Twenty percent of the Spanish population suffers from chronic pain, and between 7 and 10% from neuropathic pain. This condition, mostly caused by nerve damage, causes people to feel intense and constant pain. Treatments are scarce and often involve a large number of adverse effects that affect the patients' quality of life. For this reason, the Molecular Neuropharmacology research group, coordinated by Olga Pol at the Sant Pau Biomedical Research Institute and the UAB Institute of Neurosciences, is looking for new therapeutic possibilities that can help people who suffer from it. Now in a study, they have analyzed the effects...

We naturally think of our Founding Fathers as the heirs of the early settlers – those courageous men and women whose grandparents and great grandparents had come from England, Scotland, or Holland, fleeing religious persecution as Christians of a different denomination than the ruling class, or seeking freedom and opportunity in a new land. And many certainly were. But some of our Founding Fathers – some of the greatest heroes, in fact – were foreigners who heard about our cause and felt it in their hearts. New arrivals, from Europe or the Caribbean, who heard of the American independence movement...

Oregon Governor Kate Brown has commuted the sentences of the 17 people on the state's death row to life in prison in her final month in office - leading to fury from the victims' families. Brown, a Democrat with less than a month remaining in office, said she was using her executive clemency powers to commute the sentences and that her order will take effect on Wednesday. The decision to change the death sentences to life in prison without the possibility of parole has been met with fury from the families of the murderers' victims and government officials. Oregon has...

It's a link, the body is in the video description, it's just fine. Be blessed! Founded https://m.youtube.com/watch?v=faDlsX98hZw&t=4s

Of course most of us have never heard of this case but it is huge, The historic significance of Brunson v Adams ranks with the signing of the Declaration of Independence. I say this with no fear of contradiction as every aspect of this case bears on whether our Constitutionthat supports the very freedoms that we enjoy and that make us different from third world dictatorships. Brunson v Adams is THAT important. This case is at once scary, because the stakes involved are as high as we can go; and encouraging because the Court has accepted it, and the significance...

For at least a half-century now, every special pleader in America has made the following argument: Yeah, but what if we were black?This is supposed to be rhetorical kryptonite, capable of anathematizing "discrimination" against any group: atheists, women, gays, immigrants, illegal immigrants, the disabled, Muslims -- basically anyone except a fully abled, cis-gendered, white male born in this country.Oh my gosh! You're right -- we DO have to let girls try out for the Green Bay Packers!OK, fine, we'll hire more blind lifeguards.Of course, Shadi Abdullah is welcome to be president of our campus Hillel group.Naturally, the "What if they...

A former Department of Energy official accused of stealing a woman's suitcase from the Las Vegas airport glared at the camera in their mugshot after being arrested on the felony grand larceny charge. Sam Brinton, 35, who identifies as non-binary and uses 'they/their' pronouns, appeared in a Las Vegas courtroom on Wednesday where the judge set their bail at $15,000. A cash bond has already been posted and Brinton was not held. Brinton was charged for the luggage theft earlier this year at the Harry Reid International Airport in Las Vegas that was captured on security footage. They also face...

It all happened in a matter of seconds, from the moment the police arrived at the home of House Speaker Nancy Pelosi and encountered an intruder with a large hammer to when her husband, Paul Pelosi, was lying unconscious on the floor.“Mr. Pelosi was face down on the ground, a pool of blood by his head,” said Kyle Cagney, one of the two San Francisco police officers first to arrive in the early hours of Oct. 28, during a court hearing on Wednesday...Prosecutors on Wednesday played an audio recording of the interview that Mr. DePape gave to the police in...

TAMPA, Fla. (WFLA) — An 83-year-old Port Charlotte man who was trapped under a golf cart for several hours was rescued by an unlikely duo — two Waste Management workers. According to a release from the company, driver Alex Galarza and assistant driver Paulino Ortega were driving along their regular route Monday when they noticed the man trapped under a golf cart at the end of a Port Charlotte driveway. The workers immediately dialed 911 and started providing first aid treatment while authorities were en route. In talking to the man, the workers noticed he was showing signs of hypothermia...

Lizzo issued a rebuke Monday to critics who accused her of making music that only appeals to white people — an allegation raised in her new HBO Max documentary, “Love, Lizzo.” “[It’s] very hurtful, only because I am a Black woman, and I feel like it really challenges my identity and who I am, and diminishes that, which I think is really hurtful,” the “Juice” singer, 34, said during an appearance on “The Howard Stern Show.” SNIP “It was a Black school,” Lizzo told Vanity Fair for its November cover story. “Mostly Black and brown, Caribbean, I had Nigerian friends...

VIDEOScam the Scam is about to enter the Ninth Circle of Hell aka the notoriously brutal Fox Hill Prison in the Bahamas. After living life in a very comfy protective bubble of pampered privilege poor Sam is in for a big shock. If he so much as mentions "effective altruism" in that prison, you just know where the prisoners will shove that altruism as you can see in a few scenes in this video of what awaits him at his new abode. A hellhole where worrying about fulfilling his vegan diet will be the LEAST of his concerns.It's almost as...

PHOENIX (AP) — The U.S. government sued Arizona Gov. Doug Ducey and the state Wednesday over the placement of shipping containers as a barrier on the border with Mexico, saying it is trespassing on federal lands. The complaint filed in U.S. District Court comes three weeks before the Republican governor steps aside for Democratic Gov.-elect Katie Hobbs, who has said she opposes the construction. Ducey told U.S. officials earlier this week that Arizona stands ready to help remove the containers, which he says were placed as a temporary barrier. But he wants the U.S. government to say when it will...

On Election Day, Maricopa County, Arizona, found itself at the center of the national conversation thanks to a number of malfunctioning election machines, incredibly long lines and other issues. The county is the most populous by far in a state where Democrat Katie Hobbs won the gubernatorial challenge by a mere 0.6 percent (roughly 17,000 votes) over her Republican opponent, former local news anchor-turned-conservative firebrand Kari Lake. Because of this, Arizona State Senator Sonny Borrelli filed a lawsuit on Monday. The suit alleges that voters in the more rural Mohave County were disenfranchised by the malfeasance of Maricopa County election...

It's been 13 years since James Cameron's Avatar beat his previous blockbuster, Titanic, to become the highest grossing film ever released. But now at long last he has returned to the jungle moon of Pandora - and roughly 13 years have passed there, too. Jake Sully (Sam Worthington), his mind now permanently installed in a blue alien Na'vi body, is the chief of his clan, and he and his wife Neytiri (Zoe Saldaña) have four children. They spend their time lolling around in skimpy loincloths, thinking about how happy they are, but inevitably their Edenic and slightly risqué tranquility ends...

The Biden administration announced Tuesday that it will work to close gaps in the physical barriers along the southwest border and fix environmental and other issues with the Trump-era wall construction amid growing concerns about the federal government's ability to handle high levels of unauthorized migration. Officials said the latest work, authorized by Homeland Security Secretary Alejandro Mayorkas, will focus on Arizona, California and Texas and is aimed at addressing safety and environmental concerns brought on by the building of new or upgraded barriers along the border with Mexico. Installing drainage systems, adding safety features to roadways and remediating some...