The Fall of Constantinople 1453 Back to "Decline of the Byzantine Empire" Chronology Back to "Ottoman Empire" Chronology The siege of Constantinople, the capital of the Byzantine Empire and one of the most heavily fortified cities in the world, took place in 1453. Sultan Mehmed II, ruler of the Ottoman Turks, led the assault. The city was defended by, at most, 10,000 men. The Turks had between 100,000 and 150,000 men on their side. The siege lasted for fifty days. The Turks employed various important war tactics in taking over the city. They used huge cannon to destroy the...