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Researchers have found evidence that a coronavirus epidemic swept East Asia some 20,000 years ago and was devastating enough to leave an evolutionary imprint on the DNA of people alive today. The new study suggests that an ancient coronavirus plagued the region for many years, researchers say. The finding could have dire implications for the Covid-19 pandemic if it’s not brought under control soon through vaccination. Four other coronaviruses can also infect people, but they usually cause only mild colds. Scientists did not directly observe these coronaviruses becoming human pathogens, so they have relied on indirect clues to estimate when...

An ancient coronavirus, or a closely related pathogen, triggered an epidemic among ancestors of present-day East Asians roughly 25,000 years ago, a new study indicates.Analysis of DNA from more than 2,000 people shows that genetic changes in response to that persistent epidemic accumulated over the next 20,000 years or so, David Enard, an evolutionary geneticist at the University of Arizona in Tucson, reported April 8 at the virtual annual meeting of the American Association of Physical Anthropologists. The finding raises the possibility that some East Asians today have inherited biological adaptations to coronaviruses or closely related viruses.The discovery opens the...