For patients with stroke of recent onset or progression of stroke symptoms and no occlusion of large or medium-sized cerebral vessels, intravenous tirofiban is associated with an increased likelihood of an excellent outcome, according to a study. Wenjie Zi, M.D. and colleagues conducted a multicenter trial involving patients with ischemic stroke without occlusion of large or medium-sized vessels, a National Institutes of Health Stroke Scale score of 5 or greater, and at least one moderately to severely weak limb. Eligible patients were ineligible for thrombolysis or thrombectomy and within 24 hours of stroke; had progression of stroke symptoms soon after...