I'm a cardiologist. For my entire career I've told patients arterial stiffness can only be slowed, never undone. I may have been wrong — and I'm glad. Something recent was framed as a skincare story. It isn't. For the first time, scientists erased a form of damage considered permanent since the 1980s — in a human artery. Sugar reacts with proteins the way heat browns bread, leaving CML (Nε-carboxymethyllysine), the most abundant advanced glycation end-product. It welds onto collagen and elastin in arteries, skin, and the eye lens. Arteries stiffen. CML binds RAGE (receptor for advanced glycation end-products), fueling chronic...