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Human Proteome 'More Complex than Previously Thought' Jeffrey Tomkins, Ph.D. Once again the oft-repeated phrase "More complex than previously thought" has been used to describe new research cataloguing thousands of proteins produced from the human genome.1 This groundbreaking biotech news is undergirded by two recent papers published in the journal Nature that describe what has been called the first rough draft of the human proteome.2,3 Unlike DNA sequencing, the extraction, isolation, and identification of proteins is no easy task. To be able to characterize the large diversity of proteins in different tissues, the technologies and chemistries need to be diverse...

Scientists hail new 'map of life' By Dr David Whitehouse BBC News Online science editor A fruit fly and its protein interaction map Biologists have produced a detailed map of protein interactions in a complex organism - the fruit fly. Proteins, which are made by genes, are the building blocks of tissues as well as the basis for molecular interactions that enable an organism to live. The protein interaction map will allow a new insight into a highly complex metabolic system, similar in many ways to the human one. The research is to be published in a future issue of...