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Keyword: proteinstructure

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  • An Algorithm Set To Revolutionize 3-D Protein Structure Discovery

    04/26/2015 7:57:25 PM PDT · by 2ndDivisionVet · 21 replies
    MIT Technology Review ^ | April 23, 2015
    One of the great challenges in molecular biology is to determine the three-dimensional structure of large biomolecules such as proteins. But this is a famously difficult and time-consuming task. The standard technique is x-ray crystallography, which involves analyzing the x-ray diffraction pattern from a crystal of the molecule under investigation. That works well for molecules that form crystals easily. But many proteins, perhaps most, do not form crystals easily. And even when they do, they often take on unnatural configurations that do not resemble their natural shape. So finding another reliable way of determining the 3-D structure of large biomolecules...