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The amino acid creatine is essential for muscle and brain health, and people commonly use creatine supplements to improve exercise performance and increase muscle mass. Results from a clinical trial indicate that dietary creatine may also benefit individuals experiencing post-COVID-19 fatigue syndrome (also known as long COVID). In the trial, 12 people with post-COVID-19 fatigue syndrome were randomized to take a placebo or 4 grams of creatine monohydrate per day for six months. Creatine intake caused a significant increase in creatine levels in leg muscles and across the brain at both three-month and six-month follow-ups. Creatine supplementation also led to...

A small randomized trial in patients with post-COVID syndrome has found that hyperbaric oxygen therapy promotes restoration of the heart's ability to contract properly. The study enrolled 60 post-COVID syndrome patients with ongoing symptoms. Both hospitalized and non-hospitalized patients were included. Severe COVID cases were excluded. Patients were randomized to HBOT or a sham procedure in a 1:1 ratio. Each patient had five sessions per week over eight weeks, for a total of 40 sessions. The HBOT group received 100% oxygen through a mask at a pressure of 2 atmospheres for 90 minutes, with 5 minute air breaks every 20...

Anywhere from 10 percent to 80 percent of people experience prolonged illness and symptoms after COVID-19 infection that may last for months. This means that anywhere from 5 to 40 million people around the world may be suffering from post-COVID syndrome or long-haul COVID.Persistent symptoms have appeared in patients of all ages, even children who only had minor of COVID-19 infections, regardless of whether or not hospitalization was required. Additionally, there is no firm consensus regarding which risk factors make patients more likely to acquire long-haul COVID, although a Mayo Clinic study found three quarters of those with long-haul COVID...