Free Republic

Researchers have discovered that a natural molecule made by gut bacteria can reverse liver damage and repair the gut lining after aflatoxin exposure. The treatment may offer a new, non-toxic way to prevent and treat non-alcoholic fatty liver disease (NAFLD). The study revealed that 10-hydroxystearic acid (10-HSA), a compound produced by Lactobacillus bacteria, successfully restored gut-liver health in mice exposed to aflatoxin. Aflatoxin is a toxic substance made by mold commonly found in peanuts, corn and other crops. It is known to cause liver injury. "This is the first time a single microbial molecule has been shown to repair both...

Chronic liver disease (CLD) is a major global health concern. This life-threatening disease often progresses silently, eventually leading to worsened conditions like liver cirrhosis or liver cancer. There is currently no treatment for CLD other than liver transplantation. Vitamin D is commonly consumed for enhanced bone health. A recent study opens exciting possibilities for repurposing an inexpensive supplement as a complementary therapy for liver diseases. Prof. Hyo-Jung Kwon and his colleagues have studied the underlying mechanisms and therapeutic implications of vitamin D in liver disease. "Here, we explored the effects of vitamin D on ductular reaction and CLDs, and investigated...