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The most widely used methods for transdermal administration of the drugs are hypodermic needles, topical creams, and transdermal patches. The effect of most of the therapeutic agents is limited due to the stratum corneum layer of the skin, which serves as a barrier for the molecules and thus only a few molecules are able to reach the site of action. A new form of delivery system called the microneedles helps to enhance the delivery of the drug through this route and overcoming the various problems associated with the conventional formulations. The primary principle involves disruption of the skin layer, thus...

Aide to Wisconsin Governor Delivers Hypodermic Needles to Opponent of Stem Cell ResearchBy Todd Richmond Associated Press Writer Published: Jul 27, 2005 MADISON, Wis. (AP) - The top aide to Wisconsin's governor had hundreds of used hypodermic needles delivered to the Assembly speaker's office on behalf of a woman protesting the lawmaker's stance on stem cell research. Republican Speaker John Gard's staff immediately called police, fearing the needles, delivered July 19, might be contaminated. Dan Leistikow, a spokesman for Democratic Gov. Jim Doyle, said the needles were sheathed and posed no threat. He defended the delivery as a way to...