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Keyword: fenoprofen

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  • Repurposed drug shows promise against endometriosis-related pain in animal model (Fenoprofen reverses endometriosis)

    03/20/2024 6:41:46 PM PDT · by ConservativeMind · 7 replies
    Medical Xpress / National Institutes of Health / iScience ^ | March 18, 2024 | Tomiko T. Oskotsky et al
    Fenoprofen, a nonsteroidal anti-inflammatory drug (NSAID), successfully alleviated pain and inflammation in a rodent model of endometriosis, according to researchers. They chose the drug after using a computer algorithm to evaluate nearly 1,300 existing compounds for their ability to reverse gene expression related to endometriosis disease. Analysis by researchers using publicly available data from people with endometriosis, returned 299 candidate compounds with seven considered top candidates. These drugs included commonly used treatments for the disease, such as aspirin, as well as those not yet studied for this purpose. The researchers chose fenoprofen for further evaluation because it returned the highest...