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Keyword: fatostatin

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  • Discovery Of 'Fatostatin' A Turnoff For Fat Genes

    08/29/2009 10:17:01 PM PDT · by neverdem · 22 replies · 1,198+ views
    Medical News Today ^ | 28 Aug 2009 | Cathleen Genova
    A small molecule earlier found to have both anti-fat and anti-cancer abilities works as a literal turnoff for fat-making genes, according to a new report in the August 28th issue of the journal Chemistry and Biology, a Cell Press journal. The chemical blocks a well known master controller of fat synthesis, a transcription factor known as SREBP. That action in mice that are genetically prone to obesity causes the animals to become leaner. It also lowers the amount of fat in their livers, along with their blood sugar and cholesterol levels. "We are frankly very excited about it," said Salih...