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Keyword: eplerenone

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  • Grapefruit Warning: It Can Interact with Common Medications

    07/21/2025 7:10:18 AM PDT · by Red Badger · 37 replies
    Healthline ^ | March 15, 2023 | Medically reviewed by Dena Westphalen, PharmD — Written by Matthew Thorpe, MD, PhD
    Grapefruit and its close relatives can increase the blood levels of certain drugs and cause serious side effects. Affected drugs include some medications for blood pressure and heart rhythm, among others. Grapefruit is a delicious citrus fruit with many health benefits. However, it can interact with some common medications, altering their effects on your body. If you’re curious about the grapefruit warning on many medicines, this article will help you understand why it’s there and what your options are. Here’s a closer look at 31 common drugs that may have dangerous interactions with grapefruit, as well as some alternatives. Note:...
  • Eplerenone and Standard Therapy Cut Mortality 24% in Mild Heart Failure

    01/07/2011 10:36:22 PM PST · by neverdem · 4 replies
    Family Practice News ^ | December 2010 | PATRICE WENDLING
    Vitals Major Finding: Eplerenone reduced the risk of cardiovascular death or heart failure hospitalization by 37%, compared with placebo. Data Source: Phase III randomized trial in 2,737 patients with NYHA class II heart failure. Disclosures: EMPHASIS-HF was funded by Pfizer. Dr. Zannad reported receiving grants from and consulting for Pfizer. Two coauthors are Pfizer employees, and several others reported Pfizer grants and consultancy. CHICAGO — Adding eplerenone to standard therapy significantly cut the risk of cardiovascular death and heart failure hospitalization by more than one-third in patients with mild heart failure in the phase III EMPHASIS-HF trial. The primary composite...