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Keyword: dornasealpha

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  • Clinical trial: Repurposed drug improves outcomes for patients with severe COVID-19 pneumonia (Dornase alfa)

    07/25/2024 12:02:40 PM PDT · by ConservativeMind · 9 replies
    Medical Xpress / University College London / eLife ^ | July 16, 2024 | Joanna C. Porter et al
    A drug commonly used to treat cystic fibrosis improved outcomes for patients with severe COVID-19 pneumonia and could be used to treat other respiratory infections, according to clinical trial results. The study found that the drug dornase alfa reduced hyper-inflammation in COVID-19 pneumonia patients, which occurs when the body's immune system reacts too strongly and can lead to tissue damage and death. Since the beginning of the COVID-19 pandemic, the proportion of SARS-CoV-2 infections that result in death has fallen. This is partly down to increased immunity from prior infection or vaccination, as well as improved treatments such as dexamethasone....